Results 61 to 70 of about 189,241 (266)

Sonoenzymatically Triggered Cascading Degradation of Bioresorbable Materials for On‐Demand Transient Triboelectric Implants

Advanced Materials, EarlyView.
Our SEA strategy provides an efficient and biosafe approach for the on‐demand removal of implanted bioresorbable materials through cascading degradation that couples ultrasound‐triggered rapid mechanical disintegration with subsequent enzymatic degradation.
Jinsong Kim, Dong‐Min Lee, Youngwook Chung, Byung‐Joon Park, Hyeon Mo, Jong Won Seon, Han‐Yup Yum, Bosung Kim, Byung‐Ok Choi, Sang‐Woo Kim   +9 more
wiley   +1 more source

Successful treatment of massive thrombosis of the vena cava inferior with nephrоtic syndrome and chronic bilateral pulmonary artery thromboembolism in a patient with genetic thrombophilia

Терапевтический архив, 2012
A case is reported of a 23-year-old male patient who developed, after severe blunt injury of the lumbar region, massive thrombosis of the vena cava inferior (VCI), both renal veins, bilateral pulmonary artery thromboembolism (PATE), nephrоtic syndrome ...
Ol'ga Vladimirovna Blagova, S L Dzemeshkevich, N L Kozlovskaya, A V Nedostup, N D Sarkisova, Yu V Frolova, V V Raskin, A S Dzemeshkevich, S A Abugov, O G Skipenko, E M Shilov, V P Sedov, N V Gagarina, V E Sinitsyn, E A Mershina, E Yu Volkova, O V Blagova, S L Dzemeshkevich, N L Kozlovskaya, A V Nedostup, N D Sarkisova, Yu V Frolova, V V Raskin, A S Dzemeshkevich, S A Abugov, O G Skipenko, E M Shilov, V P Sedov, N V Gagarina, V E Sinitsyn, E A Mershina, E Yu Volkova   +31 more
doaj  

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Dabigatran Plasma Measurement to Guide the Management of Acute Bleeding and Thrombotic Complications

European Journal of Case Reports in Internal Medicine, 2018
Oral anticoagulant therapy is recommended for the prevention and treatment of venous thromboembolism and to prevent stroke in non-valvular atrial fibrillation.
Maurizio Tala, Oriana Paoletti, Claudia Dellanoce, Rossella Morandini, Carlo Valtulina, Maria Sessa, Sophie Testa   +6 more
doaj   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

DABIGATRAN ETEXILATE IN ELDERL Y PATIENTS WITH ATRIAL FIBRILLATION: WHATS NEW?

Евразийский Кардиологический Журнал, 2017
The article discusses stroke prevention in elderly patients with atrial fibrillation. The principles of choosing anticoagulant therapy in this group of patients are discussed.
O. N. Tkacheva, N. M. Vorobyeva
doaj   +1 more source

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy

International Journal of Nanomedicine, 2019
Pei-Chi Lee,1 Bo-Shen Zan,1 Li-Ting Chen,1 Tze-Wen Chung1,2 1Department of Biomedical Engineering, National Yang Ming University, Taipei 112, Taiwan; 2Drug Delivery Department, Center for Advanced Pharmaceutics and Drug Delivery Research, National Yang ...
Lee PC, Zan BS, Chen LT, Chung TW
doaj  

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source