Results 81 to 90 of about 322,983 (366)

An Anticoagulant Coating Based on a Block Phosphocholine Copolymer for Potential Applications in Blood Contact Devices

Advanced Materials Interfaces, EarlyView.
Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu, Yahong Kang, Xuebin Wang, Weijie Wang, Changsheng Liu, Hongyan Jiang, Yuan Yuan   +6 more
wiley   +1 more source

COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah, Farah Yasmin, Roha Saeed Memon, Nadia Nazir Jatoi, Ilma Saleh Savul, Sana Kazmi, Syed Abdullah Monawwer, Muhammad Daim Bin Zafar, Muhammad Sohaib Asghar, Muhammad Junaid Tahir, Ka Yiu Lee   +10 more
wiley   +1 more source

Development of a Machine Learning Model and Mobile Application to Aid in Predicting Dosage of Vitamin K Antagonists Among Indian Patients [PDF]

arXiv, 2020
Patients who undergo mechanical heart valve replacements or have conditions like Atrial Fibrillation have to take Vitamin K Antagonists (VKA) drugs to prevent coagulation of blood. These drugs have narrow therapeutic range and need to be very closely monitored due to life threatening side effects.
arxiv  

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

Advanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan, Gaofei Qian, Huikang Zhang, Feifan Wang, Qiang Tian, Dong Lei, Jianning Zhao   +6 more
wiley   +1 more source

Multi-scale simulation of thrombus formation at LVAD inlet cannula connection: Importance of Virchow's triad [PDF]

arXiv, 2020
As pump thrombosis is reduced in current-generation ventricular assist devices (VAD), adverse events such as bleeding or stroke remain at unacceptable rates. Thrombosis around the VAD inlet cannula (IC) has been highlighted as a possible source of stroke events.
arxiv  

Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease [PDF]

, 2003
Current teaching suggests that many patients are at risk for prolonged bleeding during and following invasive dental procedures, due to an acquired coagulopathy from systemic disease and/or from medications.
A Barber, AB Lumb, AD Kaye, AGG Turpie, AH Friedlander, AI Schafer, AM Ziffer, AS Gewirtz, AT Mailloux, BS Coller, C Kearon, CA Petruff, CH Mielke Jr., CL Norred, D Blinder, D Deykin, DB Petitti, DF Pawlak, DM Eisenberg, EM Hylek, F Catella-Lawson, FE Silverstein, G Palareti, G Russo, H Bagheri, H Ogiuchi, IW Scopp, J Gibson, J Harenberg, J Hirsh, J Hirsh, J Hirsh, J Leitch, J Marshall, JA Oates, JA Ware, JC O'Laughlin, JH Campbell, JN George, JN Saour, JR Vane, K Webster, L Bodner, L Mengle-Gaw, LC Tsen, LS Simon, M Akbarian, M Hurlen, M Levine, MH Eckman, MH Eckman, MJ Steinburg, MJ Troulis, MJ Wahl, MJ Wahl, MK Ang-Lee, MMW Koopman, N May, OR Beirne, P B Lockhart, P Devani, PC Amrein, PJ Sharis, R Benoliel, R De Caterina, R Hull, R Mulligan, R Mulligan, R Stern, RA Seymour, RE Alexander, RH White, RI Shorr, RT Weibert, S Cronberg, S Goldman, S H Pond, S Lippert, SC Cannegieter, SD Fihn, SE Lind, SE Lind, SI Rapaport, SJ Behrman, SR Cox, SS De Rossi, T Bandrowsky, TP Rooney, VA Ferraris, WR Bartle, WW Herman   +90 more
core   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Anticoagulant rodenticides on our public and community lands: spatial distribution of exposure and poisoning of a rare forest carnivore. [PDF]

, 2012
Anticoagulant rodenticide (AR) poisoning has emerged as a significant concern for conservation and management of non-target wildlife. The purpose for these toxicants is to suppress pest populations in agricultural or urban settings.
Barrett, Reginald H, Clifford, Deana L, Gabriel, Mourad W, Higley, J Mark, Keller, Stefan M, Matthews, Sean M, Poppenga, Robert, Purcell, Kathryn, Sacks, Benjamin N, Sweitzer, Rick A, Thompson, Craig, Wengert, Greta M, Woods, Leslie W   +12 more
core   +2 more sources

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

Similarity-based prediction of Ejection Fraction in Heart Failure Patients [PDF]

arXiv, 2022
Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments. However, due to limitations inherent in the collection process, RWE often lacks key features of patients, particularly when these features cannot be directly ...
arxiv