Results 51 to 60 of about 6,300,141 (198)

Comparative Study of Leech-Derived Tryptase Inhibitor Genes in Four Medicinal Leech Species

Biology
Leeches are aquatic annelids of significant medicinal value, known to produce a variety of antithrombotic proteins. However, the extent of interspecies variation in these bioactive components remains poorly understood.
Mingkang Xiao, Fang Zhao, Tianyu Ye, Rui Ai, Lizhou Tang, Zichao Liu, Qingqian Zeng, Zuhao Huang, Gonghua Lin   +8 more
doaj   +1 more source

A Novel Bi-Functional Fibrinolytic Enzyme with Anticoagulant and Thrombolytic Activities from a Marine-Derived Fungus Aspergillus versicolor ZLH-1

Marine Drugs, 2022
Fibrinolytic enzymes are important components in the treatment of thrombosis-associated disorders. A new bi-functional fibrinolytic enzyme, versiase, was identified from a marine-derived fungus Aspergillus versicolor ZLH-1.
Lihong Zhao, Xiuping Lin, Jingyun Fu, Jun Zhang, Wei Tang, Zengguo He   +5 more
doaj   +1 more source

Bioactive extract having blood anticoagulant activity.

, 2008
The present invention relates to the anticoagulant activity of the crude aqueous extract of Melastoma malabathricum Linn. on normal human blood.
Hamid, Muhajir, Manicam, Caroline, Abdullah, Janna Ong, Mohd Tohit, Eusni Rahayu, Sieo , Chin Chin, Seman, Zainina   +5 more
core   +1 more source

LC/MS Analysis of Saponin Fraction from the Leaves of Elaeagnus rhamnoides (L.) A. Nelson and Its Biological Properties in Different In Vitro Models

Molecules, 2020
This study focuses on saponin fraction from sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson) leaves. It has known that for example teas from sea buckthorn leaves have anti-obesity properties. The objective of our present experiments was to investigate
Jerzy Żuchowski, Bartosz Skalski, Michał Juszczak, Katarzyna Woźniak, Anna Stochmal, Beata Olas   +5 more
doaj   +1 more source

Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata

Marine Drugs, 2023
A sulfated polysaccharide (AG) was extracted and isolated from the sea cucumber H. fuscopunctata, consisting of GlcNAc, GalNAc, Gal, Fuc and lacking any uronic acid residues.
Ru Chen, Weili Wang, Ronghua Yin, Ying Pan, Chen Xu, Na Gao, Xiaodong Luo, Jinhua Zhao   +7 more
doaj   +1 more source

EFFECT OF SULFATION ON THE STRUCTURE AND ANTICOAGULANT ACTIVITY OF ULVAN EXTRACTED FROM GREEN SEAWEED ULVA RETICULATA [PDF]

, 2018
Ulvans are sulfated polysaccharides derived from the cell wall of green seaweeds. Thechemical structure of ulvan extracted from Ulva reticulata is reported, focusing on investigationof the sulfated modification of the ulvan and the changes in structure ...
Minh Thu, Quach Thi
core   +2 more sources

The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]

PLoS ONE, 2018
Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood, A Naggi, G Torri, C Page, P Rigsby, B Mulloy, E Gray   +6 more
doaj   +1 more source

Anticoagulant Property of a Sulfated Polysaccharide with Unique Structural Characteristics from the Green Alga Chaetomorpha aerea

Marine Drugs, 2023
Sulfated polysaccharides from marine algae have attracted a great amount of attentions for the development of marine drugs due to their unique structural features, and they are great potential sources of naturally occurring anticoagulant agents.
Ling Qin, Yajing Yang, Wenjun Mao
doaj   +1 more source

Anticoagulant Activities of Indobufen, an Antiplatelet Drug [PDF]

Molecules, 2018
Indobufen is a new generation of anti-platelet aggregation drug, but studies were not sufficient on its anticoagulant effects. In the present study, the anticoagulant activity of indobufen was determined by monitoring the activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT) in rabbit plasma.
Liu, Jia, Xu, Dan, Xia, Nian, Hou, Kai, Chen, Shijie, Wang, Yu, Li, Yunman   +6 more
openaire   +3 more sources

Structural Elucidation of a Glucan from Trichaster palmiferus by Its Degraded Products and Preparation of Its Sulfated Derivative as an Anticoagulant

Marine Drugs, 2023
Echinoderms have been attracting increasing attention for their polysaccharides, with unique chemical structure and enormous potential for preparing drugs to treat diseases.
Haiqiong Ma, Qingxia Yuan, Hao Tang, Hongjie Tan, Tingting Li, Shiying Wei, Jinwen Huang, Yue Yao, Yaping Hu, Shengping Zhong, Yonghong Liu, Chenghai Gao, Longyan Zhao   +12 more
doaj   +1 more source