Results 31 to 40 of about 156,819 (199)

The ISFET based heparin sensor with a monolayer of protamine as affinity ligand [PDF]

, 1995
The ion-step measuring method was used to determine absolute heparin concentrations in PBS and blood plasma with a Ta2O5 ISFET on to which a monolayer of protamine had been immobilized. Heparin is a highly negatively charged polysaccharide, which is used
Bergveld, P., Kerkhof, J.C. van, Schasfoort, R.B.M.   +2 more
core   +2 more sources

A Deep Overview of Anticoagulant Drugs: Recent Synthesis and Their Activity Assay

Indonesian Journal of Chemistry
During the unprecedented COVID-19 pandemic, anticoagulant drugs have emerged as a crucial component of treatment alongside antivirus medications.
Engrid Juni Astuti, Slamet Ibrahim, Muhammad Ali Zulfikar, Sophi Damayanti   +3 more
doaj   +1 more source

Anticoagulant Activity of Sulfated Ulvan Isolated from the Green Macroalga Ulva rigida

Marine Drugs, 2019
(1) Background: Brown and red algal sulfated polysaccharides have been widely described as anticoagulant agents. However, data on green algae, especially on the Ulva genus, are limited.
Amandine Adrien, Antoine Bonnet, Delphine Dufour, Stanislas Baudouin, Thierry Maugard, Nicolas Bridiau   +5 more
doaj   +1 more source

Isolation, fractionation and anticoagulant activity of a sulfated galactan extracted from the green algae Penicillus capitatus

Ciência Rural, 2021
: Marine algae are natural sources of macromolecules known as sulfated polysaccharides. This class of compounds has attracted the interest of Pharmaceutical Sciences due to its pharmacological anticoagulant, antiplatelet and antithrombotic properties ...
Thamyris Almeida Moreira, Bianca Barros da Costa, Regina Célia Alves Celestino, Caroline Nogueira Faria, Jéssica Lopes D’Dego Gianelli, Gustavo Ramalho Cardoso dos Santos, Bianca Fernandes Glauser, Angélica Ribeiro Soares, Paulo Antônio de Souza Mourão, Carlos Rangel Rodrigues, Leonardo Paes Cinelli   +10 more
doaj   +1 more source

Bioassay-Guided Fractionation of Melastoma malabathricum Linn. Leaf Solid Phase Extraction Fraction and Its Anticoagulant Activity

Molecules, 2015
The aims of this study were to examine the bioactive component(s) responsible for the anticoagulant activity of M. malabathricum Linn. leaf hot water crude extract via bioassay-guided fractionation and to evaluate the effect of bioactive component(s) on ...
Li Teng Khoo, Janna Ong Abdullah, Faridah Abas, Eusni Rahayu Mohd Tohit, Muhajir Hamid   +4 more
doaj   +1 more source

A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]

, 2018
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams, Adams, Akassoglou, Akassoglou, Akenami, Akenami, Albright, Alizadeh, Alonso, Amor, Antoniak, Beggs, Bidot, Bitsch, Boesen, Brkic, Bronstein, Brunetti, Castellino, Cesarman-Maus, Chapman, Chelmicka-Szorc, Claudio, Compston, Coughlin, Cuzner, Danø, Davalos, Davalos, Davidson, Davie, De Luca, Dekaban, Deschepper, Donovan, East, Ed Rainger, Engelmann, Esmon, Esmon, Fan, Fan, Farber, Feldman, Ferguson, Festoff, Field, Fiorini, Flick, Fog, Friedman, Garcia-Monco, García, Garg, Genc, Gloor, Griffin, Griffin, Guenther, Gveric, Göbel, Göbel, Göbel, Hafler, Han, Horstman, Huszak, Inaba, Inoue, Iong, Jacob, Jones, Kalaria, Kirichuk, Kirk, Kirk, Knauer, Koudriavtseva, Koudriavtseva, Koudriavtseva, Koudriavtseva, Kreutzberg, Kuhlmann, Kwon, Lane, Langer, Lassmann, Lassmann, Lassmann, Lesny, Liddelow, Lider, Lin, Lin, Lock, Lu, Mahmood, Mandoj, Marik, Mechelli, Miranda, Moll, Murray, Park, Parsons, Paterson, Perez, Persson, Persson, Petersen, Phillips, Pike, Plantone, Plumb, Putnam, Putnam, Rand, Reese, Reinhard, Roizin, Ryu, Ryu, Saberi, Savitky, Seeds, Seeds, Sheremata, Simón, Smith, Sobel, Soon, Sotnikov, Spadaro, Starossom, Starossom, Stavrou, Stolz, Teesalu, Tennent, Ugarova, Uzawa, van der Poll, Varga, Verrall, Wachowicz, Wakefield, Weisel, Whitlock, Wittinghofer, Wolter, Wright, Xue, Yadav, Yamaji, Yates, Yuksel, Zhang, Ziliotto, Zivadinov   +158 more
core   +1 more source

A Novel Bi-Functional Fibrinolytic Enzyme with Anticoagulant and Thrombolytic Activities from a Marine-Derived Fungus Aspergillus versicolor ZLH-1

Marine Drugs, 2022
Fibrinolytic enzymes are important components in the treatment of thrombosis-associated disorders. A new bi-functional fibrinolytic enzyme, versiase, was identified from a marine-derived fungus Aspergillus versicolor ZLH-1.
Lihong Zhao, Xiuping Lin, Jingyun Fu, Jun Zhang, Wei Tang, Zengguo He   +5 more
doaj   +1 more source

Thrombolysis in a stroke patient on dabigatran anticoagulation: case report and synopsis of published cases [PDF]

, 2013
We present the case of an aphasic 77-year-old stroke patient with left distal M1 occlusion who received rt-PA for thrombolysis while on oral anticoagulant treatment with dabigatran (150 mg b.i.d.).
Abruscato, Mario Giovanni Rosario, Baas, Horst, Hövelmann, Susanne, Pfeilschifter, Waltraud   +3 more
core   +2 more sources

The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]

PLoS ONE, 2018
Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood, A Naggi, G Torri, C Page, P Rigsby, B Mulloy, E Gray   +6 more
doaj   +1 more source

Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata

Marine Drugs, 2023
A sulfated polysaccharide (AG) was extracted and isolated from the sea cucumber H. fuscopunctata, consisting of GlcNAc, GalNAc, Gal, Fuc and lacking any uronic acid residues.
Ru Chen, Weili Wang, Ronghua Yin, Ying Pan, Chen Xu, Na Gao, Xiaodong Luo, Jinhua Zhao   +7 more
doaj   +1 more source