Results 31 to 40 of about 6,300,141 (198)

Heparin and related drugs:beyond anticoagulant activity [PDF]

open access: yes, 2013
Heparin has been widely used as an anticoagulant for more than 80 years. However, there is now considerable evidence that heparin also possesses anti-inflammatory activity, both experimentally and clinically.
Page, Clive
core   +1 more source

Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants [PDF]

open access: yesChest, 2017
Direct oral anticoagulants (DOACs) are the treatment of choice for most patients with atrial fibrillation and/or noncancer-associated venous thromboembolic disease. Although routine monitoring of these agents is not required, assessment of anticoagulant effect may be desirable in special situations.
Bethany T, Samuelson   +4 more
openaire   +2 more sources

The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids [PDF]

open access: yes, 2009
The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm.
Fernig, David G.   +7 more
core   +4 more sources

A Deep Overview of Anticoagulant Drugs: Recent Synthesis and Their Activity Assay

open access: yesIndonesian Journal of Chemistry
During the unprecedented COVID-19 pandemic, anticoagulant drugs have emerged as a crucial component of treatment alongside antivirus medications.
Engrid Juni Astuti   +3 more
doaj   +1 more source

Chemical Profile, Antioxidant, Anti-Proliferative, Anticoagulant and Mutagenic Effects of a Hydroalcoholic Extract of Tuscan Rosmarinus officinalis

open access: yesPlants, 2021
This study aimed to characterize the chemical profile of an ethanolic extract of Tuscan Rosmarinus officinalis (Roex) and to determine its in vitro bioactivity.
Stefania Lamponi   +4 more
doaj   +1 more source

Anticoagulant Activity of Sulfated Schizophyllan

open access: yesBioscience, Biotechnology, and Biochemistry, 1994
Sulfated schizophylians with lower anticoagulant activity and higher anti-HIV activity were prepared. Those with sulfur contents above 6% showed anticoagulant activity irrespective of molecular weight. The activity was correlated with sulfur content. The triple helical structure of sulfated schizophylians did not affect their anticoagulant activity.
Hirata, Akio   +5 more
openaire   +1 more source

Anticoagulant Activity of Sulfated Ulvan Isolated from the Green Macroalga Ulva rigida

open access: yesMarine Drugs, 2019
(1) Background: Brown and red algal sulfated polysaccharides have been widely described as anticoagulant agents. However, data on green algae, especially on the Ulva genus, are limited.
Amandine Adrien   +5 more
doaj   +1 more source

A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines

open access: yesPharmaceuticals, 2021
Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin.
Weronika Kotkowiak   +2 more
doaj   +1 more source

Cholesterol enhances phospholipid-dependent activated protein C anticoagulant activity

open access: yes, 2005
The influence of cholesterol on activated protein C (APC) anticoagulant activity in plasma and on factor Va inactivation was investigated. Anticoagulant and procoagulant activities of phosphatidylcholine/phosphatidyiserine (PC/PS) vesicles containing ...
Pecheniuk, N. M.   +2 more
core   +1 more source

Differential Anticoagulant Activity of Heparin Fragments Prepared Using Microbial Heparinase [PDF]

open access: yes, 1982
The Journal of Biological Chemistry, 257, 7310-7313Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Grant, A.   +3 more
core   +1 more source

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