Results 21 to 30 of about 156,819 (199)

Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy. [PDF]

open access: yes, 2017
We present the case of a patient with a deep vein thrombosis (DVT) who failed rivaroxaban therapy. Our patient initially presented with left lower extremity edema, erythema, and pain.
Adashek, Jacob   +6 more
core   +5 more sources

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

open access: yes, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand   +6 more
core   +9 more sources

Pharmacology complex compound of pro-gly-pro-leu with heparin: hypoglycemic, fibrinolitic and anticoagulant effects in rats with hyperglycemia

open access: yesФармация и фармакология (Пятигорск), 2019
Previously it was shown that the use of regulatory peptides of the glyprolin family helps to normalize the hemostasis system and blood glucose levels in experimental resistant hyperglycemia in rats, similar to type 2 diabetes mellitus in humans.
T. Yu. Obergan   +5 more
doaj   +1 more source

Short runs of atrial arrhythmia and stroke risk: a European-wide online survey among stroke physicians and cardiologists [PDF]

open access: yes, 2016
Methods: An online survey of cardiologists and stroke physicians was carried out to assess current management of patients with short runs of atrial arrhythmia within Europe. Results: Respondents included 311 clinicians from 32 countries.
Abdul-Rahim, A.H.   +5 more
core   +1 more source

Heparin mimetics with anticoagulant activity

open access: yesMedicinal Research Reviews, 2018
AbstractHeparin, a sulfated polysaccharide belonging to the glycosaminoglycan family, has been widely used as an anticoagulant drug for decades and remains the most commonly used parenteral anticoagulant in adults and children. However, heparin has important clinical limitations and is derived from animal sources which pose significant safety and ...
Abdullah Al Nahain   +4 more
openaire   +5 more sources

Cytoprotective Activated Protein C Averts Nlrp3 Inflammasome–Induced Ischemia-Reperfusion Injury Via Mtorc1 Inhibition [PDF]

open access: yes, 2017
Cytoprotection by activated protein C (aPC) after ischemia-reperfusion injury (IRI) is associated with apoptosis inhibition. However, IRI is hallmarked by inflammation, and hence, cell-death forms disjunct from immunologically silent apoptosis are, in ...
Al-Dabet, Moh\u27d Mohanad   +16 more
core   +2 more sources

Chemical Profile, Antioxidant, Anti-Proliferative, Anticoagulant and Mutagenic Effects of a Hydroalcoholic Extract of Tuscan Rosmarinus officinalis

open access: yesPlants, 2021
This study aimed to characterize the chemical profile of an ethanolic extract of Tuscan Rosmarinus officinalis (Roex) and to determine its in vitro bioactivity.
Stefania Lamponi   +4 more
doaj   +1 more source

Effect of anticoagulants on the plasma hyaluronidase activities [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2009
AbstractMammalian hyaluronidases (HAases) are an endo‐β‐N‐acetyl‐hexosaminidases that degrade hyaluronan (HA) and have been implicated in diverse pathophysiological functions. Several pathological conditions, such as diabetes, monoclonal gammapathy, and bladder and prostate tumors, report the distorted plasma HAase activity.
Sharma, R.   +6 more
openaire   +3 more sources

A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines

open access: yesPharmaceuticals, 2021
Aptamers constitute an answer for the growing need for targeted therapy development. One of the most well-known representatives of this group of compounds is thrombin binding aptamers (TBA) targeted towards thrombin.
Weronika Kotkowiak   +2 more
doaj   +1 more source

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