Results 61 to 70 of about 6,300,141 (198)

Cardiolipin enhances protein C pathway anticoagulant activity

, 2000
The anticoagulant activity of activated protein C (APC) was studied using factor Xa-1-stage assays of both the procoagulant and anticoagulant activities of phospholipid vesicles containing phosphatidylserine or cardiolipin as active phospholipids. In the
Hackeng, TM; id_orcid, Griffin, JH, Petaja, J, Kojima, K, Fernandez, JA   +4 more
core   +1 more source

Identification of Fibrinolytic Activity in Iranian Vipera Lebetina Venom

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Vipera lebetina lives in different areas in Iran, and its venom contains a variety of proteins with coagulant and anticoagulant activities. Fibrinolytic enzymes could have a therapeutic role in dissolution of blood clots, so, this
Zohreh Amoozgari, Maryam Cheraghzadeh, Mozhgan Noorbehbahani, Nasrin Lamuchi Deli   +3 more
doaj  

Amino Acid Profiles and Biopotentiality of Hydrolysates Obtained from Comb Penshell (Atrina pectinata) Viscera Using Subcritical Water Hydrolysis

Marine Drugs, 2021
The recovery of amino acids and other important bioactive compounds from the comb penshell (Atrina pectinata) using subcritical water hydrolysis was performed. A wide range of extraction temperatures from 140 to 290 °C was used to evaluate the release of
Hee-Jeong Lee, Vikash Chandra Roy, Truc Cong Ho, Jin-Seok Park, Yu-Rin Jeong, Seung-Chan Lee, Sung-Yeol Kim, Byung-Soo Chun   +7 more
doaj   +1 more source

Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions [PDF]

, 2015
A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone.
Simmonds, RE, Esmon Charles T., Gerd Pluschke, Alexander Stainer, Alexander Stainer (771266), Josefin Ahnström (771267), Vogel Moritz, Stainer Alexander, Wu, HL, Hua-Lin Wu (70210), Ruf, Marie-Thérèse, Pluschke, G, Belinda S. Hall, Vogel, Moritz, Ahnström Josefin, Simmonds Rachel E., Vogel, M, Hall Belinda S., Marie-Thérèse Ruf (2280196), Simmonds, Rachel E., Ogbechi Joy, Moritz Vogel, Moritz Vogel (267190), Hall, Belinda S., Stainer, Alexander, Behr, Marcel A., Katherine Bodman-Smith, Josefin Ahnström, Bodman-Smith, K, Esmon, Charles T., Ogbechi, J, Ahnström, J, Rachel E Simmonds, Charles T. Esmon, Pluschke, Gerd, Charles T Esmon, Wu, Hua-Lin, Joy Ogbechi (546561), Hua-Lin Wu, Charles T. Esmon (280612), Joy Ogbechi, Bodman-Smith Katherine, Marie-Thérèse Ruf, Esmon, CT, Katherine Bodman-Smith (771265), Belinda S. Hall (546558), Rachel E. Simmonds, Wu Hua-Lin, Ruf Marie-Thérèse, Pluschke Gerd, Ruf, MT, Ahnström, Josefin, Gerd Pluschke (7855), Ogbechi, Joy, Stainer, A, Belinda S Hall, Rachel E. Simmonds (546562), Bodman-Smith, Katherine, Hall, BS, Simmonds RE, Ruf MT, Hall BS, Wu HL, Ahnström J, Pluschke G, Ogbechi J, Esmon CT, Bodman-Smith K, Vogel M, Stainer A   +69 more
core   +2 more sources

A New Anticoagulant−Antidote Pair:  Control of Thrombin Activity by Aptamers and Porphyrins

, 2016
Cationic porphyrins have been described to bind to G-quadruplexes with high affinities. In combination with G-quadruplex containing DNA aptamers that bind and inhibit the blood clotting factor thrombin, these molecules act as true antidotes that revert ...
Astrid Joachimi (2499835), Jörg S. Hartig (840160), Günter Mayer (240591)   +2 more
core   +1 more source

ISOLATION OF SULPHATE POLYGALACTAN FROM Eucheuma alvarezii Doty AND ITS ANTICOAGULANT ACTIVITY [PDF]

, 2013
A sulphate polygalactan carrageenan was isolated from Euchema alvarezii Doty with yield 54.36%. The sulphate polygalactan was fractionated with KCl (aq) 2.5% result of a sulphate polygalactan of soluble fraction with the yield 60.34% and a sulphate ...
Al-Fath, Hanifah Nur; Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Malang (Universitas Negeri Malang) Jl. Semarang 6 Malang 65145, Indonesia, ., Sutrisno; Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Malang (Universitas Negeri Malang) Jl. Semarang 6 Malang 65145, Indonesia, ., Parlan; Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Malang (Universitas Negeri Malang) Jl. Semarang 6 Malang 65145, Indonesia   +2 more
core   +1 more source

Preparation and Characterization of <em>O</em>-Acylated Fucosylated Chondroitin Sulfate from Sea Cucumber

Marine Drugs, 2012
Fucosylated chondroitin sulfate (FuCS), a kind of complex glycosaminoglycan from sea cucumber, has potent anticoagulant activity. In order to understand the relationship between structures and activity, the depolymerized FuCS (dFuCS) was chosen to ...
Na Gao, Mingyi Wu, Shao Liu, Wu Lian, Zi Li, Jinhua Zhao   +5 more
doaj   +1 more source

The anticoagulant activity of heparins in dextrose solutions

Journal of Pharmacy and Pharmacology, 1982
AbstractChanges with time in the anti-factor Xa activity of several heparins were determined in freshly autoclaved and unautoclaved dextrose solutions. In the former, activity was raised, in the latter a reversible fall occurred at certain heparin concentrations, and the term ‘dextrose effect’ is applied to the difference in activity in the two types ...
W, Anderson, J E, Harthill
openaire   +2 more sources

Hepcidin Inhibition by Modified Heparins without Anticoagulant Activity

, 2012
Some non-anticoagulant heparins have strong anti-hepcidin activity both in vitro and in vivo, and may represent promising hepcidin antagonist with potential therapeutic ...
GIRELLI, Domenico, CASTAGNA, Annalisa, CAMPOSTRINI, Natascia, Annamaria Naggi, Federica Maccarinelli, Maura Poli, Paolo Arosio, Dario Finazzi   +7 more
core   +1 more source

Non-Anticoagulant Low Molecular Weight Heparins for Pharmaceutical Applications

, 2019
Heparin is a polypharmacological agent with anticoagulant activity. Periodate oxidation of the nonsulfated glucuronic acid residue results in non-anticoagulant heparin derivative (NACH) of reduced molecular weight.
Jianle Chen (6091952), Zhenqing Zhang (696515), Yilan Ouyang (1662616), Yanlei Yu (1480924), Xiaorui Han (1401655), Ke Xia (303441), Robert J. Linhardt (710659), Yiming Yao (2570479), Fuming Zhang (1316187)   +8 more
core   +1 more source