Results 91 to 100 of about 31,015 (230)
Anticodon Modifications in the tRNA Set of LUCA and the Fundamental Regularity in the Standard Genetic Code. [PDF]
PLoS ONE, 2016 Based on (i) an analysis of the regularities in the standard genetic code and (ii) comparative genomics of the anticodon modification machinery in the three branches of life, we derive the tRNA set and its anticodon modifications as it was present in ...
Peter T S van der Gulik, Wouter D Hoff
doaj +1 more source
Molecular Simulations of the Ribosome and Associated Translation Factors
, 2014 The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information.
Hamed H. Alsulami (532535) +3 more
core +6 more sources
Modulation of translational decoding by m6A modification of mRNA
Nature Communications, 2023 N6-methyladenosine (m6A) is an abundant, dynamic mRNA modification that regulates key steps of cellular mRNA metabolism. m6A in the mRNA coding regions inhibits translation elongation. Here, we show how m6A modulates decoding in the bacterial translation
Sakshi Jain +8 more
doaj +1 more source
Active role of elongation factor G in maintaining the mRNA reading frame during translation. [PDF]
, 2019 During translation, the ribosome moves along the mRNA one codon at a time with the help of elongation factor G (EF-G). Spontaneous changes in the translational reading frame are extremely rare, yet how the precise triplet-wise step is maintained is not ...
Belardinelli, R. +5 more
core +2 more sources
Ligase‐Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase
Current Protocols, Volume 6, Issue 1, January 2026.Abstract The growing utility of xeno‐nucleic acids (XNAs) lies in their ability to extend the reach of genetic chemistry beyond the limits imposed by natural polymers. XNAs, with their diverse chemical backbones, resist enzymatic degradation and yet retain the capacity for sequence‐defined information, and have found broad applications in biotechnology.
Natalie Khamissi +2 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 1, January 2026.By integrating comprehensive mitogenomic sequencing with detailed morphological examinations, we demonstrate a strong case for transferring Cochylis discerta from its current genus to Falseuncaria. Four complete mitogenomes of Cochylini species are sequenced and analyzed for the first time here.
Yinghui Sun +4 more
wiley +1 more source
A New method for Analysis of Biomolecules Using the BSM-SG Atomic Models [PDF]
, 2017 Biomolecules and particularly proteins and DNA exhibit some mysterious features that cannot find satisfactory explanation by quantum mechanical modes of atoms.
Sargoytchev, Stoyan Sarg
core +1 more source
Translational control in plants: from basic mechanisms to environmental and developmental responses
The Plant Journal, Volume 125, Issue 1, January 2026.SUMMARY Protein synthesis is an essential process for all living organisms and is tightly regulated to ensure the proper production of proteins needed for growth, development, and stress responses. As sessile organisms, plants have evolved distinct mechanisms to regulate translation, allowing them to adapt to their environment.
Jade Lyons +3 more
wiley +1 more source
Characterization of UVA-Induced Alterations to Transfer RNA Sequences
Biomolecules, 2020 Ultraviolet radiation (UVR) adversely affects the integrity of DNA, RNA, and their nucleoside modifications. By employing liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based RNA modification mapping approaches, we identified the transfer RNA (
Congliang Sun +2 more
doaj +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang +7 more
wiley +1 more source