Results 191 to 200 of about 31,015 (230)
Codon—anticodon pairing: The wobble hypothesis
Journal of Molecular Biology, 1966 It is suggested that while the standard base pairs may be used rather strictly in the first two positions of the triplet, there may be some wobble in the pairing of the third base. This hypothesis is explored systematically, and it is shown that such a wobble could explain the general nature of the degeneracy of the genetic code.
F. Crick
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The anticodon-anticodon complex
Journal of Molecular Biology, 1974Abstract Gel electrophoresis has been used to measure the binding between two tRNAs with complementary anticodons, tRNA Val ( Escherichia coli ) (anticodon X,A,C) and tRNA Tyr ( E. coli ) (anticodon Q,U,A). The association constant K at 0 °C was found to be 4 × 10 5 m −1 which is about three orders of magnitude greater than the association ...
J, Eisinger, N, Gross
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Trends in Biochemical Sciences, 2000
A tRNALys-specific anticodon nuclease is kept in a latent form in a rare Escherichia coli strain, complexed with a DNA restriction enzyme. A phage T4 inhibitor of DNA restriction activates anticodon nuclease, but other T4 proteins restore tRNALys. Detection of a homologous system in Neisseria and a different anticodon nuclease in colicin E5 suggest ...
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A tRNALys-specific anticodon nuclease is kept in a latent form in a rare Escherichia coli strain, complexed with a DNA restriction enzyme. A phage T4 inhibitor of DNA restriction activates anticodon nuclease, but other T4 proteins restore tRNALys. Detection of a homologous system in Neisseria and a different anticodon nuclease in colicin E5 suggest ...
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Anticodon and wobble evolution
Gene, 2004The location of the root of life within the Archaea domain close to Methanopyrus kandleri and Aeropyrum pernix on the basis of tRNA sequence clustering has allowed the tracing of evolutionary change in anticodon usages and the wobble rules governing them among different living lineages. Analysis suggests that the primitive Archaea employed simple modes
Tong, KL, Wong, JTF
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Codon-Anticodon Binding in tRNAphe
Nature New Biology, 1971THE anticodon loop of tRNAphe of baker's yeast has the sequence (5′ to 3′) AY A A MeG U MeC. The unusual base Y, adjacent to the anticodon (AA MeG), is the only nucleotide in this tRNA which fluoresces at room temperature and because it absorbs to the red of all other bases, the excitation energy is localized on it exclusively.
J, Eisinger, B, Feuer, T, Yamane
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Aminoacids and the anticodon: Anticodon interaction: A test of the stereochemical hypothesis?
Biochimie, 1981SCOPUS: ar.j ; info:eu-repo/semantics ...
Labuda, Damian, Grosjean, Henri
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Science, 1977
Much new information on codon composition is becoming available from the sequencing of molecules of DNA and RNA. The "wobble rules" for codon-anticodon pairing are applicable to this information. These rules provide for only 54 anticodons to pair with 61 codons, because the base A is not found in the first position of anticodons.
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Much new information on codon composition is becoming available from the sequencing of molecules of DNA and RNA. The "wobble rules" for codon-anticodon pairing are applicable to this information. These rules provide for only 54 anticodons to pair with 61 codons, because the base A is not found in the first position of anticodons.
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On Codon-Anticodon Interactions
1980One of the milestones on the road to the discovery of protein biosynthesis pathway was the demonstration by Lipmann’s group that the tRNA’s bring the aminoacids at the proper place on the template, that genetic information is read by tRNA’s (Chapeville et al. 1962).
H, Grosjean, H, Chantrenne
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Advances in Space Research, 1984
Anticodons are trinucleotides in transfer RNA (tRNA) molecules. The latter carry amino acids for insertion into the polypeptide sequences of proteins during the translation of messenger RNA (mRNA) molecules. Messenger RNA molecules are transcribed from genes. Evolution of tRNA molecules has resulted in a set of anticodons for the 20 amino acids that
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Anticodons are trinucleotides in transfer RNA (tRNA) molecules. The latter carry amino acids for insertion into the polypeptide sequences of proteins during the translation of messenger RNA (mRNA) molecules. Messenger RNA molecules are transcribed from genes. Evolution of tRNA molecules has resulted in a set of anticodons for the 20 amino acids that
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Rationalization of some genetic anticodonic assignments
Origins of life and evolution of the biosphere, 1985The genetic code appears to be a logic matrix in which, generally speaking, there is a correlation between the hydrophobicities of amino acids and their anticodonic nucleotides. There are several exceptions to this generality, however, and using previous data on hydrophobicity and binding constants, coupled with new data on reaction rates, we ...
J C, Lacey, L M, Hall, D W, Mullins
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