Results 91 to 100 of about 128,593 (391)

Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage

Chemistry &Biodiversity, EarlyView.
Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc, Serap Özer Yaman, Şafak Ersöz, Sevgi Kolaylı   +3 more
wiley   +1 more source

Involvement of PPAR\u3b3 in the anticonvulsant activity of EP-80317, a ghrelin receptor antagonist [PDF]

, 2017
Ghrelin, des-acyl ghrelin and other related peptides possess anticonvulsant activities. Although ghrelin and cognate peptides were shown to physiologically regulate only the ghrelin receptor, some of them were pharmacologically proved to activate the ...
Anna M. Costa, Antonio Torsello, Carmela Giordano, Chiara Lucchi, Giulia Curia, Giuseppe Biagini, Giuseppe Biagini, Giuseppina Leo, Jean Martinez, Jean-Alain Fehrentz, Jonathan Vinet, Luc Brunel, Marika Piat   +12 more
core   +3 more sources

First Report on some N2O2‐Donor Sets Tetradentate Schiff Base and Its Metal Complexes: Characterization and Antimicrobial Investigation

Chemistry &Biodiversity, EarlyView.
Mass spectrometry, UV‐Vis. spectra, thermal analysis and antimicrobial evaluation were done for a novel tetradentate Schiff base ligand (H2L) and its metal complexes. ABSTRACT The new Schiff base ligand N,N′‐thiophene‐(bis‐1‐ethyl‐6,8‐difluoro‐7‐(3‐methylpiperazin‐1‐yl)‐4‐oxo‐1,4‐dihydroquinoline‐3‐carboxylic acid) (H2L) was synthesized via ...
Amira A. Mohamed, Mohammed S. El‐Gedamy, Sadeek A. Sadeek, Hazem S. Elshafie   +3 more
wiley   +1 more source

Anticonvulsants to treat idiopathic restless legs syndrome: systematic review Anticonvulsivantes para a síndrome das pernas inquietas idiopática: revisão sistemática

Arquivos de Neuro-Psiquiatria, 2008
BACKGROUND: Restless legs syndrome (RLS) is a sensory motor disorder characterized by a distressing urge to move the legs and sometimes also other parts of the body usually accompanied by a marked sense of discomfort or pain in the leg or other affected ...
Cristiane Fiquene Conti, Márcio Moysés de Oliveira, Juliana Spelta Valbuza, Lucila Bizari F. Prado, Luciane Bizari Coin de Carvalho, Gilmar Fernandes do Prado   +5 more
doaj   +1 more source

Teratogenic effects of gabapentin on the skeletal system of Balb/C mice fetuses [PDF]

, 2009
Objectives: To evaluate the effects of gabapentin )GBP( administration on mice fetuses. Methods: This study was carried out in Birjand University of Medical Sciences during 2008.
Afshar, M., Golalipour, M.J., Hassanzadeh-Taheri, M.M., Moallem, S.-A., Tamizi, A.   +4 more
core  

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Synthesis and Biological Evaluation of Some [1,2,4]Triazolo[4,3-a]quinoxaline Derivatives as Novel Anticonvulsant Agents

ISRN Organic Chemistry, 2013
2-([1,2,4]Triazolo[4,3-a]quinoxalin-4-ylthio)acetic acid hydrazide (10) was used as a precursor for the syntheses of novel quinoxaline derivatives with potential anticonvulsant properties. The newly synthesized compounds have been characterized by IR, 1H 
Mohamed Alswah, Adel H. Ghiaty, A. El-Morsy, Kamal M El-Gamal   +3 more
semanticscholar   +1 more source

The simultaneous effect of valproic acid and gamma radiation on telomerase activity and bax and Bcl-2 protein levels in MCF-7 breast cancer cell line [PDF]

, 2015
Background: Breast cancer is one of the most prevalent types of cancer. Factors such as ionizing radiation and chemotherapeutic agents can trigger apoptosis and cancer cell death.
Asadi, J., Binabaj, M.M., Hosseini, S.A., Khoshnazar, A.K.   +3 more
core   +1 more source

Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets

The Canadian Journal of Chemical Engineering, EarlyView.
Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou, Georgia Gatidou, Athanasios S. Stasinakis, Michail S. Fountoulakis   +3 more
wiley   +1 more source