Abuse of gabapentinoids in individuals with substance use disorders
Abstract The abuse of gabapentinoids has increased rapidly, and death cases have been reported with increasing rates. This study examines the toxicological analysis data of substance abuse cases conducted after legal regulations were implemented in Türkiye.
İnci Sağlam+3 more
wiley +1 more source
Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice. [PDF]
Dahalia M+4 more
europepmc +1 more source
Sequential two-step, one-pot microwave-assisted Urech synthesis of 5-monosubstituted hydantoins from L-amino acids in water. [PDF]
Chang WJ, Liew SY, Kurz T, Tan SP.
europepmc +1 more source
Regulation of Glutamate Transporter Type 1 by TSA and the Antiepileptic Mechanism of TSA. [PDF]
Wang J+7 more
europepmc +1 more source
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley +1 more source
Toxicological analyses of the bone matrix: Successes and challenges
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano+3 more
wiley +1 more source
What do ultrasound vocalizations really mean in rats with different origins of pain? [PDF]
Yu Y, Li CL, Du R, Wang XL, Chen J.
europepmc +1 more source
Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy. [PDF]
Guerreiro D, Almeida A, Ramalho R.
europepmc +1 more source