Results 141 to 150 of about 111,563 (381)

Potential for Therapeutic Alteration of the Underlying Biology of Epilepsy

Biomedicines
Approximately 30–35% of people with epilepsy experience seizures despite taking antiseizure medications. Recurrent seizures that are independent of status epilepticus can be associated with neuronal injury and structural changes to the brain, as well as ...
Michael R. Sperling, Jurriaan M. Peters, Qian Wu, Michelle Guignet, H. Steve White, Evelyn K. Shih, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
doaj   +1 more source

Salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole, a structural and analog of acetazolamide, show interesting carbonic anhydrase inhibitory properties, diuretic, and anticonvulsant action [PDF]

, 2015
Jorge R. A. Díaz, Gerardo Camí, M. Liu‐González, Daniel Vega, Daniela Vullo, Américo Juárez, J.C. Pedregosa, Claudiu T. Supuran   +7 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Anticonvulsant effect of primidone in clinical use.

, 1990
Tatsuya Yamaguchi, Hiroko Kariyazono, Toshiro Motoya, MARUO ISHIBASHI, Hiroki Miyashita, Shinichi Arima, Hiromitsu Tanaka, MASAKO KUMAZOE   +7 more
openalex   +2 more sources

SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL IODOPHTHALAZINEDIONE DERIVATIVES AS ANTICONVULSANT AGENTS [PDF]

, 2012
Rezk R. Ayyad
openalex   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Prescription Patterns of Antiseizure Medication in Adult Patients with Epilepsy in Kazakhstan (2021–2023)

Medical Sciences
Background/Objectives: Epilepsy is a major neurological disorder associated with significant comorbidity and treatment challenges. In low- and middle-income countries, access to newer antiseizure medications (ASMs) remains limited, and prescription ...
Dina Kalinina, Temirgali Aimyshev, Alimzhan Muxunov, Zhassulan Utebekov, Gaziz Kyrgyzbay, Darkhan Kimadiev, Guldana Zhumabaeva, Abduzhappar Gaipov, Antonio Sarria-Santamera   +8 more
doaj   +1 more source

EVALUATION OF ANTICONVULSANT ACTIVITY OF MIMOSA PUDICA ROOT LINN IN SWISS ALBINO MICE

, 2016
C Prathima, Shashikumara, Thippeswamy Thippeswamy, M. K. Jayanthi   +3 more
openalex   +2 more sources

Effect of reduction of anticonvulsants on wellbeing. [PDF]

, 1982
E. Fischbacher
openalex   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source