Results 211 to 220 of about 111,563 (381)

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

open access: yesPhytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam   +14 more
wiley   +1 more source

Prevalence of Diagnosed Essential Tremor in the United States: An Administrative Claims-Based Study. [PDF]

open access: yesTremor Other Hyperkinet Mov (N Y)
Lin J   +14 more
europepmc   +1 more source

Neural Correlates of Cognitive Improvement After Virtual Reality‐Based Cognitive Remediation in Psychosis and Mood Disorders: A Randomized Controlled Trial

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Cognitive impairment in mood disorders and schizophrenia spectrum disorders hampers patients' clinical and functional outcomes. A key challenge in pro‐cognitive treatment development is the limited insight into the underlying neurocircuitry correlates of cognitive changes.
Viktoria Damgaard   +10 more
wiley   +1 more source

Associations Between Cognitive Functions and Subsequent Mood Disorder Prognosis in Low‐Risk, High‐Risk and Affected Monozygotic Twins: A Seven‐Year Follow‐Up Study

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Aberrant cognition is common among individuals at familial risk for mood disorders (MD) and those already affected. However, long‐term prospective studies are needed to determine whether specific cognitive features predict illness onset and relapse; and whether cognitive impairments reflect neurodevelopmental traits or ...
Kamilla Miskowiak   +5 more
wiley   +1 more source

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