Results 11 to 20 of about 15,890 (224)

Anticorps et bioterrorisme [PDF]

médecine/sciences, 2009
Le risque d’utilisation d’armes biologiques pourrait conduire a la reemergence de graves pathologies, telles que la peste ou la variole, maintenant eradiquees des pays developpes. La prise en charge de ce risque, appele risque biologique provoque (RBP), comporte notamment le developpement d’anticorps recombinants - qui est une voie assez sure pour ...
Philippe Thullier, Thibaut Pelat, Dominique Vidal   +2 more
openaire   +2 more sources

Lupus systémique et atteinte rénale: apport des anticorps anti-SSA [PDF]

The Pan African Medical Journal, 2015
Le but de notre travail est de déterminer le profil des auto-anticorps chez 30 patients ayant un lupus systémique avec ou sans atteinte rénale afin d'établir une corrélation clinico-immunologique entre la néphropathie lupique et ces auto-anticorps.
Kenza Baline, Karim Zaher, Hassan Fellah, Hakima Benchikhi   +3 more
doaj   +2 more sources

Anticorps et Protéides [PDF]

Bulletin de l'Académie Vétérinaire de France, 1948
Sandor Georges. Anticorps et Protéides. In: Bulletin de l'Académie Vétérinaire de France tome 101 n°8, 1948. pp. 346-348.
Sandor, G., Sandor, Georges
openaire   +5 more sources

Recherche des anticorps antiplaquettaires par cytométrie en flux, chez les patients présentant un purpura thrombopénique immunologique [PDF]

Batna Journal of Medical Sciences, 2021
En raison de la non disponibilité d’un test biologique qui confirme le diagnostic du PTI « « purpura thrombopénique immunologique », ce dernier se pose par élimination de toutes les autres causes secondaires d’une thrombopénie.
Raouf Zouitene, Mohamed Brahimi
doaj   +1 more source

The Proteolytic Cleavage of Therapeutic Monoclonal Antibody Hinge Region: More Than a Matter of Subclass

Frontiers in Immunology, 2020
The hinge region of immunoglobulin G (IgG) is involved in C1q and FcγRIIIA-expressing natural killer (NK) cell recruitment. Both heavy chains (HCs) of the hinge region can be cleaved sequentially by several proteases of the tumor/inflammatory/infectious ...
Quentin Deveuve, Laurie Lajoie, Benjamin Barrault, Gilles Thibault, Gilles Thibault   +4 more
doaj   +1 more source

Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: A national, randomized multicenter trial

Journal of Internal Medicine, Volume 294, Issue 6, Page 761-774, December 2023., 2023
Abstract Background Bevacizumab—a humanized monoclonal antibody—has been widely used to treat patients with hereditary hemorrhagic telangiectasia (HHT), but no randomized trial has yet been conducted. Methods This study is a double‐blind multicenter randomized phase 2 trial with a 1:1 active‐treatment‐to‐placebo ratio. We included patients over the age
Sophie Dupuis‐Girod, Sophie Rivière, Christian Lavigne, Anne‐Emmanuelle Fargeton, Brigitte Gilbert‐Dussardier, Vincent Grobost, Vanessa Leguy‐Seguin, Hélène Maillard, Shirine Mohamed, Evelyne Decullier, Adeline Roux, Lorraine Bernard, Jean‐Christophe Saurin, Nicolas Saroul, Frédéric Faure, Cesar Cartier, Romain Altwegg, Laurent Laccourreye, Frédéric Oberti, Marjolaine Beaudoin, Carole Dhelens, Céline Desvignes, Nicolas Azzopardi, Gilles Paintaud, Ruben Hermann, Thierry Chinet   +25 more
wiley   +1 more source

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki, Natalie Crawford, Jordan M. Eder, Andrea J. Gonzales, Thierry Olivry   +4 more
wiley   +1 more source

Long Non‐Coding RNA HOTAIR Promotes Human Osteosarcoma Proliferation, Migration through Activation of the Wnt/b‐Catenin Signaling Pathway

Journal of Oncology, Volume 2023, Issue 1, 2023., 2023
LncRNA HOTAIR exhibited different effects in human cancers. However, the role of HOTAIR was not reported in osteosarcoma. This study aimed to explore the function of HOTAIR in osteosarcoma. Firstly, we examined HOTAIR expression in breast cancer tissues by the RT‐qPCR assay and examined HOTAIR protein expression via immunocytochemistry, to chemical ...
Hang Li, Shijian Fu, Wenbo Wang, Muhammad Muddassir Ali   +3 more
wiley   +1 more source

Anticorps thérapeutiques [PDF]

médecine/sciences, 2009
Monoclonal antibodies and their derivatives such as antibody fragments, immunoconjugates and Fc fusions, represent the majority of therapeutic proteins in clinical development. Recent successes of such molecules in cancer and in the treatment of autoimmune diseases found a great hope in biotherapeutics.
Lucie Manache, Claire Dulieu, Otmane Boussif   +2 more
openaire   +1 more source

Review of MIS‐C Clinical Protocols and Diagnostic Pathways: Towards a Consensus Algorithm

CJC Pediatric &Congenital Heart Disease, Volume 1, Issue 2, Page 86-93, April 2022., 2022
Abstract Background The emergence of multisystem inflammatory syndrome in children (MIS‐C) during the severe acute respiratory syndrome coronavirus 2 pandemic led to the development of institutional clinical pathways based on expert opinion. We assessed North American paediatric centres’ adaptation to MIS‐C and analysed the degree of agreement between ...
Ashley Tritt, Ikram‐Nour Abda, Nagib Dahdah   +2 more
wiley   +1 more source