Results 11 to 20 of about 153,444 (192)

Pharmacogenetics of Antidepressants [PDF]

Frontiers in Pharmacology, 2011
Up to 60% of depressed patients do not respond completely to antidepressants (ADs) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes as genetic predictors of AD response efficacy was investigated by us and others.
Crisafulli C, Fabbri C, Porcelli S, DRAGO, ANTONIO, Spina E, DE RONCHI, DIANA, SERRETTI, ALESSANDRO   +6 more
openaire   +7 more sources

Choosing an antidepressant

Australian Prescriber, 2021
A biopsychosocial and lifestyle approach should be used when managing depression. Many patients seen in primary care do not require drug therapy Evidence-based treatments such as psychological therapies and antidepressant drugs are effective for depression.
Philip Boyce, Cassandra Ma
openaire   +3 more sources

Antidepressant Potential of Lotus corniculatus L. subsp. corniculatus: An Ethnobotany Based Approach

Molecules, 2020
As a Turkish traditional medicinal plant, aerial parts of Lotus corniculatus L. subsp. corniculatus (Fabaceae) are used as a painkiller, antihemoroidal, diuretic and sedative. In this study, the antidepressant potential of the plant has been attempted to
Fatma Tuğçe Gürağaç Dereli, Haroon Khan, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol   +3 more
doaj   +1 more source

The Effect of the 5-HT4 Agonist, Prucalopride, on a Functional Magnetic Resonance Imaging Faces Task in the Healthy Human Brain

Frontiers in Psychiatry, 2022
Depression is a common and often recurrent illness with significant negative impact on a global scale. Current antidepressants are ineffective for up to one third of people with depression, many of whom experience persistent symptomatology.
Angharad N. de Cates, Angharad N. de Cates, Marieke A. G. Martens, Marieke A. G. Martens, Lucy C. Wright, Lucy C. Wright, Cassandra D. Gould van Praag, Cassandra D. Gould van Praag, Liliana P. Capitão, Liliana P. Capitão, Daisy Gibson, Daisy Gibson, Philip J. Cowen, Philip J. Cowen, Catherine J. Harmer, Catherine J. Harmer, Catherine J. Harmer, Susannah E. Murphy, Susannah E. Murphy   +18 more
doaj   +1 more source

Antidepressants and Age [PDF]

SSRN Electronic Journal, 2011
Antidepressants as a commodity have been remarkably little-studied by economists. \ud This study shows in new data for 27 European countries that 8% of people (and \ud 10% of those middle-aged) take antidepressants each year. The probability of \ud antidepressant use is greatest among those who are middle-aged, female, \ud unemployed, poorly educated ...
Blanchflower, David G., Oswald, Andrew J.   +1 more
openaire   +3 more sources

Treatment of depression in the elderly with repetitive transcranial magnetic stimulation using theta-burst stimulation: Study protocol for a randomized, double-blind, controlled trial

Frontiers in Human Neuroscience, 2022
IntroductionTranscranial magnetic stimulation (TMS) is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy.
Leandro Valiengo, Leandro Valiengo, Leandro Valiengo, Bianca S. Pinto, Kalian A. P. Marinho, Leonardo A. Santos, Luara C. Tort, Rafael G. Benatti, Bruna B. Teixeira, Cristiane S. Miranda, Henriette B. Cardeal, Paulo J. C. Suen, Julia C. Loureiro, Renata A. R. Vaughan, Roberta A. M. P. F. Dini Mattar, Maíra Lessa, Pedro S. Oliveira, Valquíria A. Silva, Wagner Farid Gattaz, André R. Brunoni, André R. Brunoni, Orestes Vicente Forlenza   +21 more
doaj   +1 more source

AM-251, A Cannabinoid Antagonist, Modifies the Dynamics of Sleep–Wake Cycles in Rats

Frontiers in Pharmacology, 2019
Study Objectives: (a) To describe the microarchitecture of wakefulness and sleep following administrations of 5- and 10-mg/kg AM-251 in rats. (b) To develop a new statistical method to follow bout-to-bout dynamics.Method: Wistar rats (n = 6) had been ...
Emese Bogáthy, Noémi Papp, Szilvia Vas, Szilvia Vas, Szilvia Vas, György Bagdy, György Bagdy, György Bagdy, György Bagdy, László Tóthfalusi   +9 more
doaj   +1 more source

Is diazepam an antidepressant? [PDF]

British Journal of Psychiatry, 1989
In double-blind sequential study, diazepam was compared with the proven antidepressant moclobemide, in patients with atypical depression. Both agents significantly improved depression ratings over eight weeks of treatment. Diazepam was a significantly better antidepressant than moclobemide at four weeks, although not at eight weeks. All patients ceased
Brian Davies, John Tiller, Kay P. Maguire, Isaac Schweitzer   +3 more
openaire   +2 more sources

Neural Predictors of the Antidepressant Placebo Response

Pharmaceuticals, 2019
The antidepressant placebo response remains a barrier to the development of novel therapies for depression, despite decades of efforts to identify and methodologically address its clinical correlates.
Danielle Rette, Erin McDonald, Dan V. Iosifescu, Katherine A. Collins   +3 more
doaj   +1 more source

Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex

Frontiers in Pharmacology, 2019
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat mood and anxiety disorders. Chronic treatment with this antidepressant drug is thought to favor functional recovery by promoting structural and molecular changes in several ...
Estibaliz Ampuero, Mauricio Cerda, Steffen Härtel, Steffen Härtel, Francisco Javier Rubio, Solange Massa, Paula Cubillos, Lorena Abarzúa-Catalán, Rodrigo Sandoval, Albert M. Galaburda, Ursula Wyneken   +10 more
doaj   +1 more source