Results 41 to 50 of about 153,444 (192)

DRUG REPOSITIONING: Revisiting the basic psychopharmacological mechanism of action for agomelatine and where it should be classified?

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2019
Concerning Agomelatine, as of this present moment and deeply analyzing things from the psychopharmacological point of view, the utmost important question yet to be answered is “why should the drug Agomelatine be regarded as an antidepressant agent when ...
Olumuyiwa John Fasipe, Oluwatosin Beatrice Ibiyemi-Fasipe, Peter Ehizokhale Akhideno, Muyiwa Samuel Fageyinbo   +3 more
doaj   +1 more source

How can we improve antidepressant adherence in the management of depression? A targeted review and 10 clinical recommendations

Brazilian Journal of Psychiatry
Adherence to antidepressants is crucial for optimal treatment outcomes when treating depressive disorders. However, poor adherence is common among patients prescribed antidepressants.
Marco Solmi, Alessandro Miola, Giovanni Croatto, Giorgio Pigato, Angela Favaro, Michele Fornaro, Michael Berk, Lee Smith, Joao Quevedo, Michael Maes, Christoph U. Correll, André F. Carvalho   +11 more
doaj   +1 more source

In Vivo Gastroprotective and Antidepressant Effects of Iridoids, Verbascoside and Tenuifloroside from Castilleja tenuiflora Benth

Molecules, 2019
Stress is an important factor in the etiology of some illnesses such as gastric ulcers and depression. Castilleja tenuiflora Benth. (Orobanchaceae) is used in Mexican traditional medicine for the treatment of gastrointestinal diseases and nervous ...
Ricardo López-Rodríguez, Maribel Herrera-Ruiz, Gabriela Trejo-Tapia, Blanca Eda Domínguez-Mendoza, Manasés González-Cortazar, Alejandro Zamilpa   +5 more
doaj   +1 more source

Synthesis and Antidepressant Activity Profile of Some Novel Benzothiazole Derivatives

Molecules, 2017
Within the scope of our new antidepressant drug development efforts, in this study, we synthesized eight novel benzothiazole derivatives 3a–3h. The chemical structures of the synthesized compounds were elucidated by spectroscopic methods.
Ümide Demir Özkay, Ceren Kaya, Ulviye Acar Çevik, Özgür Devrim Can   +3 more
doaj   +1 more source

Antidepressants in adolescence

Australian Prescriber, 2022
In adolescence, antidepressants are second-line treatment options after psychological therapy for anxiety and obsessive compulsive disorder. They may be first- or second-line options for severe cases of major depressive disorder. The response to antidepressant treatment is generally good for anxiety and obsessive compulsive disorder, but is less ...
openaire   +2 more sources

Assessment of Antidepressant Effect of the Aerial Parts of Micromeria myrtifolia Boiss. & Hohen on Mice

Molecules, 2019
The currently available antidepressant agents necessitate the development of newer alternatives because of their serious adverse effects and costs. Traditional medicinal knowledge is likely the key that opens the door to discover new medicines.
Esra Küpeli Akkol, Fatma Tuğçe Gürağaç Dereli, Mert Ilhan   +2 more
doaj   +1 more source

Analytical methods for determination of selective serotonin reuptake inhibitor antidepressants

Reviews in Analytical Chemistry, 2011
Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression. SSRIs are classified as fluoxetine, paroxetine, escitalopram, citalopram, sertraline, and fluvoxamine.
Şentürk Zühre, Saka Cafer, Teğin İbrahim   +2 more
doaj   +1 more source

The antidepressant debate [PDF]

British Journal of Psychiatry, 2002
There has been an extensive debate recently in the North American medical literature and general press concerning the efficacy of antidepressant drugs. Little of this has reached the European press.
openaire   +2 more sources

Intermittent fasting produces antidepressant-like effects by modulating dopamine D1 receptors in the medial prefrontal cortex

Neurobiology of Disease
Nutritional psychiatry has gained increasing attention, particularly in exploring dietary interventions for depression treatment. As a potential non-drug intervention, intermittent fasting (IF) has gradually attracted the interest of researchers, but its
Jingjing Piao, Hongyu Chen, Xinmiao Piao, Ziqian Cheng, Fangyi Zhao, Ranji Cui, Bingjin Li   +6 more
doaj  

Industry withdrawal from psychiatric medication development

Brazilian Journal of Psychiatry, 2014
Between 1950 and 1969, on a serendipitous basis, psychiatric drug development flourished. However, there has been a steep decline in the development of new medication classes.
Donald F. Klein, Ira D. Glick
doaj   +1 more source