Results 41 to 50 of about 254,619 (233)
Current Pharmaceutical Design, 2009 The pathophysiology of mood disorders involves several genetic and social predisposing factors, as well as a dysregulated response to a chronic stressor, i.e. chronic pain. Our present view that depression involves a dysfunction of the monoaminergic system is a result of important clinical and preclinical observations over the past 40 years.
Berrocoso, E. +3 more
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Do antidepressants cure or create abnormal brain states? [PDF]
, 2006 Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley +55 more
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Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]
, 2020 Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F +5 more
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Pharmacology of Antidepressants [PDF]
Psychopathology, 1987 Presently in the United States, 21 compounds have been approved by the Food and Drug Administration as antidepressants. Two additional drugs marketed outside the United States as antidepressants have been approved for obsessive-compulsive disorder.
openaire +4 more sources
Pharmaceuticals, 2019 Medicinal plants such as Aloysia polystachya are often used in the treatment of psychiatric diseases, including anxiety- and depression-related humor disturbances. In folk medicine, A.
Nayara Costa de Melo +9 more
doaj +1 more source
Fluoxetine: a case history of its discovery and preclinical development [PDF]
, 2014 Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N +20 more
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Frontiers in Psychiatry, 2021 The interplay between tuberculosis and depression has been problematic since the humoralists. Over the centuries similarities in disease management have transpired.
Martie Van Der Walt, Karen H. Keddy
doaj +1 more source
Ketamine: NMDA receptors and beyond [PDF]
, 2016 Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi +2 more
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Behavioral and Developmental Changes in Brown Trout After Exposure to the Antidepressant Venlafaxine
Frontiers in Environmental Science, 2021 During the last decades, depression has been diagnosed in increasing numbers, accompanied by rising prescription rates of antidepressants. Concomitantly, these pharmaceuticals are frequently detected in surface waters. Serotonin and noradrenalin reuptake
Michael Ziegler +9 more
doaj +1 more source
Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]
, 2009 This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core +1 more source