Results 71 to 80 of about 267,421 (217)
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2019 Concerning Agomelatine, as of this present moment and deeply analyzing things from the psychopharmacological point of view, the utmost important question yet to be answered is “why should the drug Agomelatine be regarded as an antidepressant agent when ...
Olumuyiwa John Fasipe +3 more
doaj +1 more source
Linear mixed models to handle missing at random data in trial-based economic evaluations [PDF]
arXiv, 2022 Trial-based cost-effectiveness analyses (CEAs) are an important source of evidence in the assessment of health interventions. In these studies, cost and effectiveness outcomes are commonly measured at multiple time points, but some observations may be missing.
arxiv
Brazilian Journal of PsychiatryAdherence to antidepressants is crucial for optimal treatment outcomes when treating depressive disorders. However, poor adherence is common among patients prescribed antidepressants.
Marco Solmi +11 more
doaj +1 more source
Molecules, 2019 Stress is an important factor in the etiology of some illnesses such as gastric ulcers and depression. Castilleja tenuiflora Benth. (Orobanchaceae) is used in Mexican traditional medicine for the treatment of gastrointestinal diseases and nervous ...
Ricardo López-Rodríguez +5 more
doaj +1 more source
More green space is related to less antidepressant prescription rates in the Netherlands: A Bayesian geoadditive quantile regression approach [PDF]
Environmental Research 2018, 2018 Exposure to green space seems to be beneficial for self-reported mental health. In this study we used an objective health indicator, namely antidepressant prescription rates. Current studies rely exclusively upon mean regression models assuming linear associations.
arxiv
Molecular Psychiatry, 2016 Inflammatory cytokines are commonly elevated in acute depression and are associated with resistance to monoaminergic treatment. To examine the potential role of cytokines in the pathogenesis and treatment of depression, we carried out a systematic review
N. Kappelmann +4 more
semanticscholar +1 more source
Combining Cox Regressions Across a Heterogeneous Distributed Research Network Facing Small and Zero Counts [PDF]
arXiv, 2021 Studies of the effects of medical interventions increasingly take place in distributed research settings using data from multiple clinical data sources including electronic health records and administrative claims. In such settings, privacy concerns typically prohibit sharing of individual patient data, and instead, analyses can only utilize summary ...
arxiv
Nature Communications, 2019 Impaired function in the medial prefrontal cortex (mPFC) contributes to depression, and the therapeutic response produced by novel rapid-acting antidepressants such as ketamine are mediated by mPFC activity.
Brendan D. Hare +5 more
semanticscholar +1 more source
Synthesis and Antidepressant Activity Profile of Some Novel Benzothiazole Derivatives
Molecules, 2017 Within the scope of our new antidepressant drug development efforts, in this study, we synthesized eight novel benzothiazole derivatives 3a–3h. The chemical structures of the synthesized compounds were elucidated by spectroscopic methods.
Ümide Demir Özkay +3 more
doaj +1 more source
Multiply robust estimators in longitudinal studies with missing data under control-based imputation [PDF]
arXiv, 2021 Longitudinal studies are often subject to missing data. The ICH E9(R1) addendum addresses the importance of defining a treatment effect estimand with the consideration of intercurrent events. Jump-to-reference (J2R) is one classically envisioned control-based scenario for the treatment effect evaluation using the hypothetical strategy, where the ...
arxiv