Results 71 to 80 of about 391,178 (335)
British medical journal, 2017 Objective To examine off-label indications for antidepressants in primary care and determine the level of scientific support for off-label prescribing. Design Descriptive study of antidepressant prescriptions written by primary care physicians using an ...
Jenna Wong +5 more
semanticscholar +1 more source
Advanced Materials, EarlyView.Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim +6 more
wiley +1 more source
Research progress of non-monoamine antidepressants
Stress and Brain, 2021 Major depressive disorder (MDD) is a recurring mental illness that has brought severe physical and psychological burdens to people around the world and caused heavy medical and economic burdens on society.
Huan Zhang, Bo Wang, Xiaohua Cao
doaj +1 more source
Probiotic‐Based Materials as Living Therapeutics
Advanced Materials, EarlyView.Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
wiley +1 more source
Primum non nocere: An evolutionary analysis of whether antidepressants do more harm than good
Frontiers in Psychology, 2012 Antidepressant medications are the first-line treatment for people meeting current diagnostic criteria for major depressive disorder. Most antidepressants are designed to perturb the neurotransmitter serotonin—an evolutionarily ancient biochemical found ...
Paul William Andrews +5 more
doaj +1 more source
De‐Saturation of Single‐Atom Copper Catalysts for Accelerating Propargylic Substitution Reactions
Advanced Materials, EarlyView.De‐saturation of copper‐based single‐atom catalysts (De‐sat SACs) are realized by a KOH‐mediated Joule thermal shock strategy. Benefiting from the under‐saturation coordination environment of single‐atom Cu center, De‐sat Cu SACs exhibit remarkable catalytic activity in propargylic substitution reactions, tolerating a broad range of nucleophiles (N–, C–
Qilong Cai +12 more
wiley +1 more source
BMC Neuroscience, 2010 Background The molecular and biological mechanisms by which many antidepressants function are based on the monoamine depletion hypothesis. However, the entire cascade of mechanisms responsible for the therapeutic effect of antidepressants has not yet ...
Shin Minkyu +8 more
doaj +1 more source
Photoredox‐Catalyzed Synthesis of a Novel Class of Fluoroalkyl Pyrazolones
Advanced Synthesis &Catalysis, EarlyView.A photoredox strategy enables regioselective synthesis of fluoroalkyl 2‐pyrazolin‐5‐ones via radical addition and cyclization. This mild, metal‐free method shows a broad substrate scope, operates in batch and flow systems, and offers a sustainable approach to fluorinated heterocycles with potential applications in medicinal chemistry.
Emanuele F. Pissinati +3 more
wiley +1 more source
Is the Risk of Preterm Birth and Low Birth Weight Affected by the Use of Antidepressant Agents during Pregnancy? A Population-Based Investigation. [PDF]
PLoS ONE, 2016 Untreated depression during pregnancy increases the risk of morbidity and mortality in the mother and child. Therefore, specific treatments are required for this population.The study aimed to investigating the effect of antidepressant medication used ...
Anna Cantarutti +4 more
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European Psychiatry, 2022 Introduction Depressive disorders are one of the most frequent psychiatric comorbidity in epilepsy and they have a negative impact on the quality of life. Depression often requires antidepressant treatment.
M.M. Gutiérrez Rodríguez +5 more
doaj +1 more source