Results 81 to 90 of about 191,413 (246)

Adherence to antidepressants

open access: yesArchives of Pharmacy Practice, 2013
While major depression is considered a frequent mental illness there are ongoing reports of high non-adherence to antidepressant medications which places suffers at high risk for relapse, recurrence, or greater impairment,. The World Health Organization (
Abimbola Farinde
doaj   +1 more source

Serum p‐tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder

open access: yesAnnals of Neurology, EarlyView.
Objective Assess the performance of serum phosphorylated tau 217 (p‐tau217) and neurofilament light chain (NfL) in predicting risk of cognitive impairment or phenoconversion to dementia in individuals with iRBD. Methods We measured serum p‐tau217 and NfL levels by electrochemiluminescence across 4 polysomnographically confirmed iRBD cohorts (n = 300 ...
Shijun Yan   +7 more
wiley   +1 more source

Comparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis

open access: yesBritish medical journal, 2015
Study question What are the benefits and harms of second generation antidepressants and cognitive behavioral therapies (CBTs) in the initial treatment of a current episode of major depressive disorder in adults?
H. Amick   +12 more
semanticscholar   +1 more source

Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case–Control Study and Call for a Consensus

open access: yesAnnals of Neurology, EarlyView.
Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
Anna B. Szabo   +14 more
wiley   +1 more source

Antidepressants in the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis.

open access: yesPLoS ONE, 2016
BackgroundAntidepressants have been empirically used in the treatment of functional dyspepsia (FD). However, results from recent clinical trials investigating their efficacy are conflicting.
Yaoyao Lu   +3 more
doaj   +1 more source

Pharmacogenetics of antidepressants

open access: yesFrontiers in Pharmacology, 2011
Up to 60% of depressed patients do not respond completely to antidepressants (AD) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes
Concetta eCrisafulli   +6 more
doaj   +1 more source

Speech Biomarkers From Smartphone Calls Track Progression in REM Sleep Behavior Disorder and Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective This 24‐month longitudinal study involving isolated rapid eye movement sleep behavior disorder (iRBD), early‐stage Parkinson's disease (PD), and matched healthy control subjects aimed to assess whether acoustic speech features from real‐world smartphone calls provide passive progressive biomarkers in synucleinopathies.
Michal Šimek   +11 more
wiley   +1 more source

Antidepressants and akatishia

open access: yesPsychiatry and Behavioral Sciences, 2013
Common adverse effects associated with antidepressants such as headache, nause or vomitting, sedation, insomnia and sexual dysfunction are well known; however our knowledge about the relationship between antidepressants and akathisia is limited ...
Yakup Albayrak, Murat Kuloğlu
doaj   +1 more source

Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study

open access: yesAnnals of Neurology, EarlyView.
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim   +6 more
wiley   +1 more source

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