Adjunctive antidepressive pharmacotherapy in schizophrenia patients
European Psychiatry, 2021 Depressive symptoms during long-term course of schizophrenia constitute an important and frequent clinical problem. They may occur either as stand-alone major depressive episodes (MDEs) or as part of the schizophrenic negative syndrome.
M. Zink
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Unveiling the interoception impairment in various major depressive disorder stages. [PDF]
CNS Neurosci TherIn this study, interoception impairments, beginning in MDD's preclinical phase and escalating during its clinical stage, were found to predictively impact all primary symptom clusters, particularly emotional symptoms. Internal validation underscored their significant role in improving diagnostic accuracy and predictive capabilities for MDD, which ...
Zhou H +9 more
europepmc +2 more sources
Efficacy of bupropion and cognitive behavioral therapy in the treatment of methamphetamine use disorder: a systematic review and meta-analysis [PDF]
Brazilian Journal of Psychiatry, 2023 Objectives: We assessed the efficacy of cognitive behavioral therapy and bupropion compared to cognitive behavioral therapy alone for methamphetamine use disorder. Methods: The selection criteria for this systematic review study with meta-analysis were
Luis Fernando Maya Apuy +2 more
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Anxiolytic and antidepressant effect of zinc on rats and its impact on general behavioural parameters [PDF]
Vojnosanitetski Pregled, 2013 Background/Aim. Zinc is an essential element which has considerable interaction with gamma-aminobutyric acid A type receptors (GABAA) and glutamate receptors in the central nervous system (CNS).
Samardžić Janko +8 more
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Antidepressive Effectiveness of Amisulpride, Aripiprazole, and Olanzapine in Patients with Schizophrenia Spectrum Disorders: A Secondary Outcome Analysis of a Pragmatic, Randomized Trial (BeSt InTro) [PDF]
, 2023 Background Depressive symptoms are frequent in schizophrenia and associated with a poorer outcome. Currently, the optimal treatment for depressive symptoms in schizophrenia remains undetermined.
Alisauskiene, Renata +14 more
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Annals medicus, 2023 Antimicrobial resistance results from the widespread use of antimicrobial agents and is a significant obstacle to the effectiveness of these agents. Numerous methods are used to overcome this problem with moderate success.
Y. Kolben +4 more
semanticscholar +1 more source
Depressive symptoms in psychotic disorders : Trajectories of depression and antidepressive effectiveness of antipsychotic medication [PDF]
, 2023 Postponed access: the file will be accessible after 2023-10-16Background: Depressive symptoms are common in psychotic disorders and contribute to impaired functioning, a poorer quality of life, elevated relapse rate and suicide risk.
Kjelby, Eirik
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Frontiers in Psychiatry, 2020 BackgroundAntidepressant treatment is one of the most effective ways of relieving or curing depressive symptoms in patients with major depressive disorder (MDD).
Li Duan +7 more
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A dose-effect network meta-analysis model: an application in antidepressants [PDF]
, 2021 Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA applications typically ignore the role that drugs dosage play on the results.
arxiv +1 more source
Second generation androgen receptor antagonists and challenges in prostate cancer treatment
Cell Death and Disease, 2022 Prostate cancer is a hormone-dependent malignancy, whose onset and progression are closely related to the activity of the androgen receptor (AR) signaling pathway.
Yanhua Chen +4 more
semanticscholar +1 more source