Results 31 to 40 of about 66,382 (184)
Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]
, 2020 In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia +3 more
core +1 more source
Cancers, 2018 Second-generation androgen receptor axis-targeted (ARAT) agents, namely abiraterone and enzalutamide, enable stronger blockade of the androgen receptor (AR) axis and longer survival of men with castration-resistant prostate cancer (CRPC).
Y. Kita +6 more
semanticscholar +1 more source
Antidepressant use and spatial social capital [PDF]
arXiv, 2023 Social capital may help individuals maintain their mental health. Most empirical work based on small-scale surveys finds that bonding social capital and cohesive social networks are critical for mental well-being, while bridging social capital and diverse networks are considered less important.
arxiv
AMISULPRIDE AS AN AUGMENTATION AGENT IN TREATMENT RESISTANT DEPRESSION: A CASE SERIES AND REVIEW OF THE LITERATURE [PDF]
, 2019 Amisulpride (AMS) in low dosage has been used effectively for treatment of dysthymia. Yet there is a dearth of reports on its use as an augmentation agent in therapy-resistant depression.
Hans Rittmannsberger
core +2 more sources
Estimation of the marginal effect of antidepressants on body mass index under confounding and endogenous covariate-driven monitoring times [PDF]
arXiv, 2021 In studying the marginal effect of antidepressants on body mass index using electronic health records data, we face several challenges. Patients' characteristics can affect the exposure (confounding) as well as the timing of routine visits (measurement process), and those characteristics may be altered following a visit which can create dependencies ...
arxiv
PLoS ONE, 2015 Background The treatment of hepatitis C (HCV) infections has significantly changed in the past few years due to the introduction of direct-acting antiviral agents (DAAs).
Thanthima Suwanthawornkul +4 more
semanticscholar +1 more source
Antimicrobial Agents and Chemotherapy, 2020 Due to the increase of antifungal drug resistance and difficulties associated with drug administration, new antifungal agents for invasive fungal infections are needed.
S. Chu +6 more
semanticscholar +1 more source
Analise Demografica e Socioeconomica do Uso e do Acesso a Medicamentos Antidepressivos no Brasil [PDF]
arXiv, 2021 Depressive disorders, in addition to causing direct negative impacts on health, are also responsible for imposing substantial costs on society. In relation to the treatment of depression, antidepressants have proven effective, and, to the World Health Organization, access to psychotropic drugs for people with mental illnesses offers a chance of ...
arxiv
Clinics, 2015 OBJECTIVE: The purpose of this study was to evaluate the effectiveness of contrast-enhanced ultrasound with a second-generation contrast agent in distinguishing between occlusion and pseudo-occlusion of the cervical internal carotid artery, comparing it ...
C. Ventura +5 more
semanticscholar +1 more source
Nonparametric Bayesian Approach to Treatment Ranking in Network Meta-Analysis with Application to Comparisons of Antidepressants [PDF]
arXiv, 2022 Network meta-analysis is a powerful tool to synthesize evidence from independent studies and compare multiple treatments simultaneously. A critical task of performing a network meta-analysis is to offer ranks of all available treatment options for a specific disease outcome. Frequently, the estimated treatment rankings are accompanied by a large amount
arxiv