Results 1 to 10 of about 10,009 (73)
Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies
CNS Neuroscience &Therapeutics, Volume 29, Issue 9, Page 2397-2412, September 2023., 2023 Abstract Depression is a common but severe mood disorder with a very high prevalence across the general population. Depression is of global concern and poses a threat to human physical and mental health. Ferulic acid (FA) is a natural active ingredient that has antioxidative, anti‐inflammatory, and free radical scavenging properties.
Xiaoyu Dong, Dongxue Zhao
wiley +1 more source
iMeta, Volume 2, Issue 3, August 2023., 2023 We successfully isolated Maca‐EVs using ultracentrifugation and tested its antidepressant effects in the unpredictable chronic mild stress mice. Maca‐EVs increased serum serotonin (5‐HT) levels probably via the gut microbiota and metabolism modulation.
Rui Hong +14 more
wiley +1 more source
Increased risk of depression after Guillain‐Barré syndrome
Muscle &Nerve, Volume 67, Issue 6, Page 497-505, June 2023., 2023 Abstract Introduction/Aims Guillain‐Barré syndrome (GBS) is a potentially life‐threatening disorder, and some patients may develop subsequent depression related to traumatic stress or permanent loss of motor function. We determined the short‐term (0 to 2 years) and long‐term (>2 years) risk of depression after GBS.
Lotte Sahin Levison +2 more
wiley +1 more source
The Use of Antidepressive Agents and Bone Mineral Density in Women: A Meta-Analysis
International Journal of Environmental Research and Public Health, 2018 Antidepressive agents are one of the fastest-growing classes of prescribed drugs. However, the effects of antidepressive agents on bone density are controversial.
J. U. Schweiger +6 more
semanticscholar +1 more source
Novel drug developmental strategies for treatment‐resistant depression
British Journal of Pharmacology, Volume 179, Issue 6, Page 1146-1186, March 2022., 2022 Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment‐resistant depression (TRD). Limiting factors of successful drug development in the last decades were the lack of (1) knowledge of pathophysiology, (2) translational ...
Éva Borbély +5 more
wiley +1 more source
Antidepressant use and stroke or mortality risk in the elderly
European Journal of Neurology, Volume 29, Issue 2, Page 469-477, February 2022., 2022 In real‐world data of the elderly population, it was found that the risk of experiencing stroke or death in antidepressant users during and up to 1 year after exposure was higher compared to non‐users, even after adjustment for possible confounders. Abstract Background and purpose Current evidence on antidepressant‐related stroke or mortality risk is ...
Begüm Irmak Ön +7 more
wiley +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Green synthesis of nanoparticles has emerged as an effective and environmentally friendly method. Therefore, the current investigation is based on the green synthesis of zinc oxide nanoparticles (ZnO‐NPs) using plant extract of Sanvitalia procumbens (S. procumbens) that act as a capping and reducing agent. S.
Yasir Rashid +6 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Background. Depression is a major cause of disability and most antidepressant medicines are ineffective owing to their high toxicity and numerous adverse effects. As a result, there is an urgent need to find new effective treatment methods. This paper aims to investigate the effect and mechanism of total saikosaponins (TSS) on depression‐like behaviors
Zhicong Zhou +6 more
wiley +1 more source
The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen +3 more
wiley +1 more source
Depression, antidepressant use, and breast cancer incidence: results from the E3N prospective cohort
Psychiatry and Clinical Neurosciences, Volume 79, Issue 9, Page 554-560, September 2025.Aim Depression and antidepressant drugs may both impact breast cancer incidence, potentially in opposite directions. The few epidemiological studies attempting to disentangle their effects have been inconclusive. We aimed to assess within the same prospective cohort the association between depression, antidepressant use, and breast cancer risk, while ...
Romain Colle +7 more
wiley +1 more source