Rhabdomyolysis as a manifestation of clomipramine poisoning [PDF]
CONTEXT: Tricyclic antidepressive agents are widely used in suicide attempts and present a variety of deleterious effects. Rhabdomyolysis is a rare complication of such poisoning.
Nathalie Oliveira de Santana +1 more
doaj +4 more sources
The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline
A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings.
Ji-Jian Chow, MRCP +2 more
doaj +1 more source
Aims: Conflicting data exist on whether an association exists between antidepressants and the risk of major adverse cardiovascular events (MACEs) in patients with depression.
Ha Young Jang +8 more
doaj +1 more source
PET studies of the serotonin system in major depression and its treatment [PDF]
The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core +1 more source
Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P +8 more
core +1 more source
Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B. +3 more
core +1 more source
Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia [PDF]
Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they
Aguilar Salvatierra, Antonio +3 more
core +1 more source
Do antidepressants cure or create abnormal brain states? [PDF]
Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley +55 more
core +3 more sources
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
core +1 more source
Antidepressants versus placebo for depression in primary care [PDF]
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Arroll, Bruce +7 more
core +3 more sources

