Results 1 to 10 of about 56,664 (214)
Rhabdomyolysis as a manifestation of clomipramine poisoning [PDF]
São Paulo Medical Journal, 2013 CONTEXT: Tricyclic antidepressive agents are widely used in suicide attempts and present a variety of deleterious effects. Rhabdomyolysis is a rare complication of such poisoning.
Nathalie Oliveira de Santana +1 more
doaj +4 more sources
Comprehensive Analysis Reveals the Potential Diagnostic Value of Biomarkers Associated With Aging and Circadian Rhythm in Knee Osteoarthritis. [PDF]
Orthop SurgThis study employed transcriptomic analysis and Mendelian randomization to identify diagnostic and therapeutic biomarkers associated with aging‐circadian rhythm in knee osteoarthritis. Further functional and molecular mechanism analyses were conducted to elucidate their roles in knee osteoarthritis, providing a theoretical basis for clinical diagnosis ...
Li H +7 more
europepmc +2 more sources
Frontiers in Pharmacology, 2020 Aims: Conflicting data exist on whether an association exists between antidepressants and the risk of major adverse cardiovascular events (MACEs) in patients with depression.
Ha Young Jang +8 more
doaj +1 more source
Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies
CNS Neuroscience &Therapeutics, Volume 29, Issue 9, Page 2397-2412, September 2023., 2023 Abstract Depression is a common but severe mood disorder with a very high prevalence across the general population. Depression is of global concern and poses a threat to human physical and mental health. Ferulic acid (FA) is a natural active ingredient that has antioxidative, anti‐inflammatory, and free radical scavenging properties.
Xiaoyu Dong, Dongxue Zhao
wiley +1 more source
iMeta, Volume 2, Issue 3, August 2023., 2023 We successfully isolated Maca‐EVs using ultracentrifugation and tested its antidepressant effects in the unpredictable chronic mild stress mice. Maca‐EVs increased serum serotonin (5‐HT) levels probably via the gut microbiota and metabolism modulation.
Rui Hong +14 more
wiley +1 more source
A dose-effect network meta-analysis model: an application in antidepressants [PDF]
, 2021 Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA applications typically ignore the role that drugs dosage play on the results.
arxiv +1 more source
Increased risk of depression after Guillain‐Barré syndrome
Muscle &Nerve, Volume 67, Issue 6, Page 497-505, June 2023., 2023 Abstract Introduction/Aims Guillain‐Barré syndrome (GBS) is a potentially life‐threatening disorder, and some patients may develop subsequent depression related to traumatic stress or permanent loss of motor function. We determined the short‐term (0 to 2 years) and long‐term (>2 years) risk of depression after GBS.
Lotte Sahin Levison +2 more
wiley +1 more source
Novel drug developmental strategies for treatment‐resistant depression
British Journal of Pharmacology, Volume 179, Issue 6, Page 1146-1186, March 2022., 2022 Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment‐resistant depression (TRD). Limiting factors of successful drug development in the last decades were the lack of (1) knowledge of pathophysiology, (2) translational ...
Éva Borbély +5 more
wiley +1 more source
Antidepressant use and stroke or mortality risk in the elderly
European Journal of Neurology, Volume 29, Issue 2, Page 469-477, February 2022., 2022 In real‐world data of the elderly population, it was found that the risk of experiencing stroke or death in antidepressant users during and up to 1 year after exposure was higher compared to non‐users, even after adjustment for possible confounders. Abstract Background and purpose Current evidence on antidepressant‐related stroke or mortality risk is ...
Begüm Irmak Ön +7 more
wiley +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Green synthesis of nanoparticles has emerged as an effective and environmentally friendly method. Therefore, the current investigation is based on the green synthesis of zinc oxide nanoparticles (ZnO‐NPs) using plant extract of Sanvitalia procumbens (S. procumbens) that act as a capping and reducing agent. S.
Yasir Rashid +6 more
wiley +1 more source