Results 41 to 50 of about 10,947 (175)
Aims In many countries, pain is the most common indication for use of antidepressants in older adults. We reviewed the evidence from randomized controlled trials on the efficacy and safety of antidepressants, compared to all alternatives for pain in older adults (aged ≥65 years).
Sujita W. Narayan+10 more
wiley +1 more source
Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A.+9 more
core +1 more source
Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han+5 more
wiley +1 more source
Smoking and antidepressants pharmacokinetics: a systematic review [PDF]
Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes.
Donato, H+3 more
core +1 more source
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde+2 more
wiley +1 more source
Hipertensão arterial sistêmica e depressão [PDF]
Despite the high prevalence of depression and hypertension, the relationship between the two diseases has received little attention. This paper reviews the epidemiological, pathophysiological, and prognostic aspects of this association, as well as its ...
Azul, João Batista Serro+3 more
core +3 more sources
Antidepressant prescribing in Australian primary care: time to reevaluate
Medical Journal of Australia, Volume 222, Issue 9, Page 430-432, May 2025.
Katharine A Wallis+2 more
wiley +1 more source
Common Pediatric Problems: Hypospadias, Enuresis, and Circumcision [PDF]
Three topics of common pediatric interest from the urologist’s viewpoint are congenital hypospadias, persistent enuresis, and complications of elective circumcision.
Texter, John H.
core +1 more source
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis [PDF]
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether ...
Andreatini, R.+13 more
core +3 more sources
Antidepressant monotherapy is a first-line treatment for depression; however, not all sufferers will adequately respond to treatment. When treating a patient with treatment-resistant depression, the clinician needs to consider all factors which may ...
Beasley+47 more
core +1 more source