Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han+5 more
wiley +1 more source
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde+2 more
wiley +1 more source
A prospective naturalistic study of antidepressant-induced jitteriness/anxiety syndrome
Tsuyoto Harada, Ken Inada, Kazuo Yamada, Kaoru Sakamoto, Jun Ishigooka Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan Objective: Patients often develop neuropsychiatric symptoms such as anxiety and ...
Harada T+4 more
doaj
Use of Desipramine for the Treatment of Overactive Bladder Refractory to Antimuscarinic Therapy [PDF]
Purpose: To evaluate the use of desipramine in the treatment of overactive bladder (OAB). Materials and Methods: We retrospectively evaluated 43 patients who were treated with desipramine for OAB refractory to antimuscarinic therapy.
Bagadiya, N.+4 more
core +2 more sources
The Potent And Selective α4β2*/α6*-Nicotinic Acetylcholine Receptor Partial Agonist 2-[5-[5-((S)Azetidin-2-Ylmethoxy)-3-Pyridinyl]-3-Isoxazolyl]Ethanol Demonstrates Antidepressive-Like Behavior In Animal Models And A Favorable Adme-Tox Profile [PDF]
Preclinical and clinical studies demonstrated that the inhibition of cholinergic supersensitivity through nicotinic antagonists and partial agonists can be used successfully to treat depressed patients, especially those who are poor responders to ...
Brunner, Dani+13 more
core +2 more sources
Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder [PDF]
Background There is emerging evidence that antidepressants may be effective in preventing patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra-high risk (UHR) of psychotic disorder, from transitioning to ...
Hashimoto, Kenji+4 more
core +3 more sources
Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]
OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de+7 more
core +3 more sources
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis [PDF]
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether ...
Andreatini, R.+13 more
core +3 more sources
Common Pediatric Problems: Hypospadias, Enuresis, and Circumcision [PDF]
Three topics of common pediatric interest from the urologist’s viewpoint are congenital hypospadias, persistent enuresis, and complications of elective circumcision.
Texter, John H.
core +1 more source
Cost-effectiveness analysis of pharmaceutical treatment options in the first-line management of major depressive disorder in Belgium [PDF]
The objective of this study was to assess the cost effectiveness of commonly used antidepressants as first-line treatment of major depressive disorder (MDD) in Belgium.
Annemans, Lieven+5 more
core +2 more sources