Results 41 to 50 of about 56,664 (214)
Aims In many countries, pain is the most common indication for use of antidepressants in older adults. We reviewed the evidence from randomized controlled trials on the efficacy and safety of antidepressants, compared to all alternatives for pain in older adults (aged ≥65 years).
Sujita W. Narayan+10 more
wiley +1 more source
利用三碘甲狀腺氨酸強化療法治療對於三環抗抑鬱藥物無效的濫用藥物病人 [PDF]
We report on two substance misusers with depression resistant to tricyclic antidepressant treatment who responded to triiodothyronine augmentation.
Ho, TP, Kan, CK
core
Comparative efficacy and acceptability of seven augmentation agents for treatment-resistant depression: A multiple-treatments meta-analysis [PDF]
Background. Treatment-resistant depression (TRD) is a therapeutic challenge for clinicians. Augmentation pharmacotherapy is effective for TRD, but it is still unclear which augmentation agent is most efficacious. Objective.
Hong-Bo Qi, Shuai Huang, Xing Wang
core +3 more sources
Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han+5 more
wiley +1 more source
Sinus tachycardia facilitates ventricular conduction delay and sustained ventricular tachyarrhythmias during tricyclic antidepressant overdose. We hypothesized that impeding sinus tachycardia with the specific bradycardia agent, UL-FS 49, would reduce the incidence of ventricular tachyarrhythmia caused by tricyclic antidepressant overdose and tested ...
Steven D. Nelson+2 more
openaire +4 more sources
Coronary artery disease and depression [PDF]
Coronary artery disease (CAD) as well as depression are both highly prevalent diseases. Both cause a significant decrease in quality of life for the patient and impose a significant economic burden on society.
Langewitz, Wolf+3 more
core
Successful Suicide in a Child: Depression-Related or Paroxetine-Induced? [PDF]
Background: Children and adolescents are prone to develop psychiatric problems after stressful life events. These problems need appropriate treatment because of negative consequences like disease-related suicide.
Aghakhani, K+3 more
core +1 more source
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde+2 more
wiley +1 more source
SERTRALINE AND MIRTAZAPINE AS GERIATRIC ANTIDEPRESSANTS [PDF]
Background: Depression within the geriatric patient population is an important issue as it is associated with increased mortality. Such depression may have a different aetiology to that in younger patients and be associated with comorbid chronic physical
Bhogle, Madhavi, Holland, Jonathon
core +1 more source
Dibenzo[1,2,5]thiadiazepines are non-competitive GABAA receptor antagonists [PDF]
"A new process for obtaining dibenzo[c,f][1,2,5]thiadiazepines (DBTDs) and their effects on GABAA receptors of guinea pig myenteric neurons are described. Synthesis of DBTD derivatives began with two commercial aromatic compounds.
Carlos Barajas López+8 more
core +3 more sources