Results 41 to 50 of about 10,863 (191)

Ginsenoside Rg1: A Neuroprotective Natural Dammarane‐Type Triterpenoid Saponin With Anti‐Depressive Properties

open access: yesCNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han   +5 more
wiley   +1 more source

A target trial emulation comparing the antidepressant effectiveness of selective serotonin reuptake inhibitors (SSRIs) highlighting the importance of patent‐related confounding by indication

open access: yesActa Psychiatrica Scandinavica, Volume 150, Issue 4, Page 198-208, October 2024.
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde   +2 more
wiley   +1 more source

A prospective naturalistic study of antidepressant-induced jitteriness/anxiety syndrome

open access: yesNeuropsychiatric Disease and Treatment, 2014
Tsuyoto Harada, Ken Inada, Kazuo Yamada, Kaoru Sakamoto, Jun Ishigooka Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan Objective: Patients often develop neuropsychiatric symptoms such as anxiety and ...
Harada T   +4 more
doaj  

Use of Desipramine for the Treatment of Overactive Bladder Refractory to Antimuscarinic Therapy [PDF]

open access: yes, 2013
Purpose: To evaluate the use of desipramine in the treatment of overactive bladder (OAB). Materials and Methods: We retrospectively evaluated 43 patients who were treated with desipramine for OAB refractory to antimuscarinic therapy.
Bagadiya, N.   +4 more
core   +2 more sources

The Potent And Selective α4β2*/α6*-Nicotinic Acetylcholine Receptor Partial Agonist 2-[5-[5-((S)Azetidin-2-Ylmethoxy)-3-Pyridinyl]-3-Isoxazolyl]Ethanol Demonstrates Antidepressive-Like Behavior In Animal Models And A Favorable Adme-Tox Profile [PDF]

open access: yes, 2014
Preclinical and clinical studies demonstrated that the inhibition of cholinergic supersensitivity through nicotinic antagonists and partial agonists can be used successfully to treat depressed patients, especially those who are poor responders to ...
Brunner, Dani   +13 more
core   +2 more sources

Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder [PDF]

open access: yes, 2011
Background There is emerging evidence that antidepressants may be effective in preventing patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra-high risk (UHR) of psychotic disorder, from transitioning to ...
Hashimoto, Kenji   +4 more
core   +3 more sources

Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]

open access: yes, 2009
OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de   +7 more
core   +3 more sources

The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis [PDF]

open access: yes, 2001
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether ...
Andreatini, R.   +13 more
core   +3 more sources

Common Pediatric Problems: Hypospadias, Enuresis, and Circumcision [PDF]

open access: yes, 1978
Three topics of common pediatric interest from the urologist’s viewpoint are congenital hypospadias, persistent enuresis, and complications of elective circumcision.
Texter, John H.
core   +1 more source

Cost-effectiveness analysis of pharmaceutical treatment options in the first-line management of major depressive disorder in Belgium [PDF]

open access: yes, 2014
The objective of this study was to assess the cost effectiveness of commonly used antidepressants as first-line treatment of major depressive disorder (MDD) in Belgium.
Annemans, Lieven   +5 more
core   +2 more sources

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