Anxiolytic and antidepressant effect of zinc on rats and its impact on general behavioural parameters [PDF]
Background/Aim. Zinc is an essential element which has considerable interaction with gamma-aminobutyric acid A type receptors (GABAA) and glutamate receptors in the central nervous system (CNS).
Samardžić Janko+8 more
doaj +1 more source
A Bayesian dose-response meta-analysis model: simulation study and application [PDF]
Dose-response models express the effect of different dose or exposure levels on a specific outcome. In meta-analysis, where aggregated-level data is available, dose-response evidence is synthesized using either one-stage or two-stage models in a frequentist setting. We propose a hierarchical dose-response model implemented in a Bayesian framework.
arxiv +1 more source
Mood Disorders Are Glial Disorders: Evidence from In Vivo Studies [PDF]
It has recently been suggested that mood disorders can be characterized by glial pathology as indicated by histopathological postmortem findings. Here, we review studies investigating the glial marker S100B in serum of patients with mood disorders.
Abdul-Khaliq, Hashim+5 more
core +3 more sources
Evaluation of Overactive Bladder in Male Antidepressant Users: A Prospective Study [PDF]
Purpose In this study, we investigated overactive bladder (OAB) functions in male patients who used antidepressant drugs (ADs) that were previously examined in female patients, based on conflicting data in literature regarding the effects of AD on OAB ...
Volkan Solmaz+6 more
doaj +1 more source
Designing AI for Trust and Collaboration in Time-Constrained Medical Decisions: A Sociotechnical Lens [PDF]
Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying machine learning models may help improve the treatment selection process, but often fail in clinical practice due to
arxiv +1 more source
Phytotherapy in zoo animals [PDF]
Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann ...
Hoby, S., Walkenhorst, M., Wenker, C.
core +1 more source
Anesthetic Considerations for Patients on Psychotropic Drug Therapies
Psychotropic drugs are used in the treatment of psychiatric and non-psychiatric conditions. Many patients who are on psychotropic medications may present for procedures requiring anesthesia.
Monica W. Harbell+5 more
doaj +1 more source
Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P+8 more
core +1 more source
Depressive symptoms in psychotic disorders : Trajectories of depression and antidepressive effectiveness of antipsychotic medication [PDF]
Postponed access: the file will be accessible after 2023-10-16Background: Depressive symptoms are common in psychotic disorders and contribute to impaired functioning, a poorer quality of life, elevated relapse rate and suicide risk.
Kjelby, Eirik
core +1 more source
Use of psychiatric drugs in Dermatology, [PDF]
Patients with psychocutaneous disorders often refuse psychiatric intervention in their first consultations, leaving initial management to the dermatologist.
Magda Blessmann Weber+2 more
doaj +1 more source