Results 41 to 50 of about 3,249,142 (188)

Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]

, 2009
OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de, Daud, Fernanda Vasquez, Ferreira Filho, Celso, Ferreira, Celso, Ferreira, Marcelo, Meneghini, Adriano, Murad, Neif, Valenti, Vitor Engrácia   +7 more
core   +4 more sources

High Prevalence of Psychological Symptoms, Sexual Dysfunction, and Prolonged Medical Leave Two Years After Acute Leukemia Diagnosis—Patient Reported Outcome in Sweden

eJHaem, Volume 6, Issue 5, October 2025.
ABSTRACT Introduction With the purpose of identifying unmet needs of patients with acute leukemia, survivors were identified from the Swedish National Acute Leukemia registries. Methods At six months and at two years from diagnosis, patients were requested by mail to report outcome with focus on depression, sick leave, and sexual dysfunction.
Emma Bergfelt Lennmyr, Anna Lübking, Marie Abrahamsson, Gunnar Juliusson, Martin Höglund, Heléne Hallböök   +5 more
wiley   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González, Yahira Guzman, Nadia Juliana Proaños, Rosa‐Helena Bustos, María Aconcha, Ivan Guerrero, Laura Alejandra Martinez, Michael Berk, Seetal Dodd   +8 more
wiley   +1 more source

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen, Cille Bülow, Kim Dalhoff, David Peick Sonne   +3 more
wiley   +1 more source

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A., Ebel, Jana-Fabienne, Hose, Matthias [u.v.m.], Japtok, Lukasz, Klopfleisch, Robert, Meiners, Jana, Palmieri, Vittoria, Schumacher, Fabian, Yusuf, Ayan Mohamud, Zöller, Julia   +9 more
core   +1 more source

Association Between Depression and Risk of Hypertension: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 9, September 2025.
This meta‐analysis of 36 studies shows a significant link between depression and hypertension risk (OR = 1.198, 95% CI: 1‐086‐1.321; HR = 1.277, 95% CI: 1.159‐1.408). It advocates for mental health screening in cardiovascular care. ABSTRACT Background Hypertension and depression are major global health concerns, with increasing evidence suggesting a ...
Prakasini Satapathy, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Ganesh Bushi, Mahendra Singh, Sanjit Sah, Awakash Turkar, S. Govinda Rao, Khang Wen Goh, Muhammed Shabil, Edward Mawejje   +13 more
wiley   +1 more source

The Association of Metabolic Syndrome with the Initiation of Antidepressive Agents: Real-World Data Analysis of Administrative Claims and Health Examinations [PDF]

, 2022
Takahiro Imaizumi, Takuya Toda, Michitaka Maekawa, Daisuke Sakurai, Yuta Hagiwara, Yukiko Yoshida, Masahiko Ando, Shoichi Maruyama   +7 more
openalex   +1 more source

Automatic summarization of MEDLINE citations for evidence-based medical treatment: A topic-oriented evaluation [PDF]

, 2008
As the number of electronic biomedical textual resources increases, it becomes harder for physicians to find useful answers at the point of care. Information retrieval applications provide access to databases; however, little research has been done on ...
Fiszman, Marcelo, Demner-Fushman, Dina, Kilicoglu, Halil, Rindflesch, Thomas C.   +3 more
core   +1 more source

LC‐MS and FTIR‐Based Characterization of Flavonoid‐Rich Extract of Hyoscyamus albus L. Plant and its Multifunctional Bioactivities

ChemistrySelect, Volume 10, Issue 34, September 8, 2025.
Investigation of flavonoid extract of Hyoscyamus albus L. Abstract The current study aimed to determine the phytochemical composition of the flavonoid‐rich extract of Hyoscyamus albus L. (FEHA), collected from the Khenchela region, and to investigate its multiple bioactivities. Phytochemical profiling was explored using LC‐MS and FTIR.
Nour Elhouda Ayeb, Kenza Kadi, Dalila Addad, Abdecharif Boumaza, Kamel Nagaz, Nadjwa Aissani, Amina Bouzana, Sabrina Lekmine, Fehmi Boufahja, Hassan A Rudayni, Stefania Garzoli, Hamdi Bendif   +11 more
wiley   +1 more source

Self unbound: ego dissolution in psychedelic experience [PDF]

, 2017
Users of psychedelic drugs often report that their sense of being a self or ‘I’ distinct from the rest of the world has diminished or altogether dissolved.
Gerrans, Philip, Letheby, Chris
core   +2 more sources