Results 41 to 50 of about 3,072 (115)

Mood Disorders Are Glial Disorders: Evidence from In Vivo Studies [PDF]

, 2010
It has recently been suggested that mood disorders can be characterized by glial pathology as indicated by histopathological postmortem findings. Here, we review studies investigating the glial marker S100B in serum of patients with mood disorders.
Abdul-Khaliq, Hashim, Blasig, Ingolf E., Mueller, Karsten, Sacher, Julia, Schroeter, Matthias L., Steiner, Johann   +5 more
core   +3 more sources

Licorice (glycyrrhiza glabra) extracts-suitable pharmacological interventions for covid-19? a review [PDF]

, 2021
Even though vaccination has started against COVID-19, people should continue maintaining personal and social caution as it takes months or years to get everyone vaccinated, and we are not sure how long the vaccine remains efficacious.
Abraham, Joji, Florentine, Singarayer
core   +2 more sources

Contribution of physiological dynamics in predicting major depressive disorder severity

Psychophysiology, Volume 62, Issue 2, February 2025.
Abstract This study aimed to explore the physiological dynamics of cognitive stress in patients with Major Depressive Disorder (MDD) and design a multiparametric model for objectively measuring severity of depression. Physiological signal recordings from 40 MDD patients and 40 healthy controls were collected in a baseline stage, in a stress‐inducing ...
Esther García Pagès, Spyridon Kontaxis, Sara Siddi, Mar Posadas‐de Miguel, Concepción de la Cámara, Maria Luisa Bernal, Thais Castro Ribeiro, Pablo Laguna, Llorenç Badiella, Raquel Bailón, Josep Maria Haro, Jordi Aguiló   +11 more
wiley   +1 more source

The Potent And Selective α4β2*/α6*-Nicotinic Acetylcholine Receptor Partial Agonist 2-[5-[5-((S)Azetidin-2-Ylmethoxy)-3-Pyridinyl]-3-Isoxazolyl]Ethanol Demonstrates Antidepressive-Like Behavior In Animal Models And A Favorable Adme-Tox Profile [PDF]

, 2014
Preclinical and clinical studies demonstrated that the inhibition of cholinergic supersensitivity through nicotinic antagonists and partial agonists can be used successfully to treat depressed patients, especially those who are poor responders to ...
Brunner, Dani, Chang, Yong, Eaton, J. Brek, Hanania, Taleen, Kozikowski, Alan P., Li, Guan Nan, Liu, Qiang, Lukas, Ronald J., Sabath, Emily, van Breemen, Richard B., Whiteaker, Paul, Wu, Jie, Yu, Li Fang, Zhang, Han Kun   +13 more
core   +2 more sources

Nicorandil Ameliorates Depression‐Like Behaviors After Traumatic Brain Injury by Suppressing Ferroptosis Through the SLC7A11/GPX4 Axis in the Hippocampus

Brain and Behavior, Volume 15, Issue 1, January 2025.
Nicorandil administration significantly attenuates depression‐like behavior in rats with TBI. Mechanistically, nicorandil suppresses ferroptosis via promoting the SLC7A11/GPX4 axis in the hippocampus of rats with TBI, thus ameliorating depression‐like symptoms induced by TBI. Nicorandil: Nic.
Yao‐Ran Tu, Ming Tan, Yao Li, De‐Quan Hong, Fan Niu   +4 more
wiley   +1 more source

Breast ecchymosis: Unusual complication of an antidepressant agent

International Journal of Surgery Case Reports, 2014
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that is safely used for treatment of psychosomatic disorders. Despite being associated with a low side effect profile, it has been reported to cause hematological side effects including vaginal bleeding, epistaxis, purpura, hematuria, intracranial bleeding, and rectal bleeding.
Sami Akbulut, Yusuf Yagmur, Mehmet Babur, Serdar Gumus   +3 more
openaire   +3 more sources

Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways

Brain and Behavior, Volume 15, Issue 1, January 2025.
Agmatine significantly reduced tremors, ameliorated anxiety‐like behaviors, and attenuated harmaline‐induced locomotor deficits. At the molecular level, agmatine significantly suppressed the overexpression of Lingo‐1 elicited by harmaline. Moreover, IL‐6 expression was attenuated to an extent comparable to control levels.
Zeynab Pirmoradi, Zahra Esmaili, Mohsen Nakhaie, Kristi A. Kohlmeier, Mohammad Shabani, Moazamehosadat Razavinasab, Mehran Ilaghi   +6 more
wiley   +1 more source

Coronary artery disease and depression [PDF]

, 2017
Coronary artery disease (CAD) as well as depression are both highly prevalent diseases. Both cause a significant decrease in quality of life for the patient and impose a significant economic burden on society.
Langewitz, Wolf, Osterwalder, Remo H., Pfisterer, Matthias E., Zellweger, Michael J.   +3 more
core  

Hipertensão arterial sistêmica e depressão [PDF]

, 2005
Despite the high prevalence of depression and hypertension, the relationship between the two diseases has received little attention. This paper reviews the epidemiological, pathophysiological, and prognostic aspects of this association, as well as its ...
Azul, João Batista Serro, Lotufo Neto, Francisco, Scalco, Andréia Zavaloni, Scalco, Mônica Zavaloni   +3 more
core   +3 more sources

Mitochondrial Dysfunction Induced by Sertraline, an Antidepressant Agent [PDF]

Toxicological Sciences, 2012
Sertraline, a selective serotonin reuptake inhibitor, has been used for the treatment of depression. Although it is generally considered safe, cases of sertraline-associated liver injury have been documented; however, the possible mechanism of sertraline-associated hepatotoxicity is entirely unknown.
Letha H. Couch, Lei Guo, Jia-Long Fang, Masahiro Higuchi, Yan Li   +4 more
openaire   +3 more sources