The Potent And Selective α4β2*/α6*-Nicotinic Acetylcholine Receptor Partial Agonist 2-[5-[5-((S)Azetidin-2-Ylmethoxy)-3-Pyridinyl]-3-Isoxazolyl]Ethanol Demonstrates Antidepressive-Like Behavior In Animal Models And A Favorable Adme-Tox Profile [PDF]
, 2014 Preclinical and clinical studies demonstrated that the inhibition of cholinergic supersensitivity through nicotinic antagonists and partial agonists can be used successfully to treat depressed patients, especially those who are poor responders to ...
Brunner, Dani +13 more
core +2 more sources
Разработка и регистрация лекарственных средств, 2023 Introduction. Among the various animal models of depression used to study the pathogenesis of depression and to evaluate the antidepressant action of new compounds, models based on social stress are characterized by high constructive, face and predictive
G. G. Gaisina +4 more
doaj +1 more source
Antidepressant use and spatial social capital [PDF]
arXiv, 2023 Social capital may help individuals maintain their mental health. Most empirical work based on small-scale surveys finds that bonding social capital and cohesive social networks are critical for mental well-being, while bridging social capital and diverse networks are considered less important.
arxiv
The medicalization of life: An interdisciplinary approach
Heliyon, 2023 In recent years, consumption of antidepressant and psychotropic drugs has skyrocketed and, although contemporary life clearly involves countless conflicts, the same can be said of human beings throughout their respective historical moments.Part of the ...
María de la Luz Casas Martínez
doaj
BMC Cancer, 2021 Background Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease.
Isabelle Rydén +7 more
doaj +1 more source
Hepatic adverse events during highly active antiretroviral therapy containing nevirapine: a case report [PDF]
, 2002 BACKGROUND: Hepatotoxicity is one of the most serious complications of highly active antiretroviral therapy (HAART). The aim of this report is to analyse an HIV infected patient on HAART including nevirapine and taking antidepressive agents, with acute ...
Gökengin, Deniz, Yamazhan, Tansu
core +3 more sources
Journal of Aziz Fatimah Medical and Dental College, 2022 Objective: To assess the anti-depressant and anxiolytic effect of tramadol as compared to imipramine (approved antidepressant) in acute and chronic doses in rats.
Fiza Soomro +3 more
doaj +1 more source
Estimation of the marginal effect of antidepressants on body mass index under confounding and endogenous covariate-driven monitoring times [PDF]
arXiv, 2021 In studying the marginal effect of antidepressants on body mass index using electronic health records data, we face several challenges. Patients' characteristics can affect the exposure (confounding) as well as the timing of routine visits (measurement process), and those characteristics may be altered following a visit which can create dependencies ...
arxiv
Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder [PDF]
, 2011 Background There is emerging evidence that antidepressants may be effective in preventing patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra-high risk (UHR) of psychotic disorder, from transitioning to ...
Hashimoto, Kenji +4 more
core +3 more sources
Analise Demografica e Socioeconomica do Uso e do Acesso a Medicamentos Antidepressivos no Brasil [PDF]
arXiv, 2021 Depressive disorders, in addition to causing direct negative impacts on health, are also responsible for imposing substantial costs on society. In relation to the treatment of depression, antidepressants have proven effective, and, to the World Health Organization, access to psychotropic drugs for people with mental illnesses offers a chance of ...
arxiv