Results 61 to 70 of about 134,759 (289)

Effect of Pleurotus fossulatus Aqueous Extract on Biochemical Properties of Liver and Kidney in Streptozotocin-Induced Diabetic Rat

Diabetes, Metabolic Syndrome and Obesity, 2020
Sushil Dubey, Chandrabhan Yadav, Anand Bajpeyee, Mohan P Singh Centre of Biotechnology, University of Allahabad, Prayagraj, Uttar Pradesh, IndiaCorrespondence: Mohan P SinghCoordinator, Centre of Biotechnology Institute of Interdisciplinary Studies (IIDS)
Dubey S, Yadav C, Bajpeyee A, Singh MP
doaj  

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Synthesis and biological evaluation of stilbene derivatives coupled to NO donors as potential antidiabetic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The work is focused on the design of drugs that prevent and treat diabetes and its complications. A novel class of stilbene derivatives were prepared by coupling NO donors of alkyl nitrate and were fully characterised by NMR and other techniques.
Bing Wang, Teng Liu, Zhongyu Wu, Lei Zhang, Jie Sun, Xiaojing Wang   +5 more
doaj   +1 more source

Utilization of whey for formulation of whey jamun juice ice pops with antidiabetic potential

Food Frontiers, 2021
Whey utilization has been a subject of much research, as it has a very high biological oxygen demand (BOD) and must be treated prior to disposal. Several strategies, such as isolation of whey proteins, bioconversions of lactose to ethanol, and methane ...
Yasmeena Jan, Muneeb Malik, Vasudha Sharma, Mifftha Yaseen, Jinku Bora, Afrozul Haq   +5 more
doaj   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

AMYLASE INHIBITION AND FREE RADICAL SCAVENGING ACTIVITIES OF WHITE TURMERIC EXTRACT AND FRACTIONS

Jurnal Teknologi dan Industri Pangan, 2018
Diabetes is the most common endocrinal disorder characterized by hyperglycemia and long-term complications. Recently, the development of antidiabetic drugs have focused on natural products with va-rious mechanisms such as the inhibition of α-amylase ...
Dwiyati Pujimulyani, Wisnu Adi Yulianto, Astuti Setyowati, Seila Arumwardana, Annisa Amalia, Hanna Sari W. Kusuma, Ervi Afifah   +6 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Evaluation of in vivo antidiabetic, antidyslipidemic and in vitro antioxidant activities of hydromethanolic root extract of Datura stramonium L. (Solanaceae)

Journal of Experimental Pharmacology, 2019
Yaschilal Muche Belayneh,1 Zewdu Birhanu,2 Eshetie Melese Birru,2 Gedefaw Getenet1 1Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Pharmacology, School of Pharmacy, College of Medicine ...
Belayneh YM, Birhanu Z, Birru EM, Getenet G   +3 more
doaj  

Antidiabetic and nephroprotective potential of polyherbal self-fermented Ariṣṭa formulation: Evidence-based research

Ancient Science of Life, 2018
Background: Ayurvedic Ariṣṭa preparations hold an age-old heritage in the prevention and cure of metabolic disorders and associated complications. Aim: The aim of the study was to study the antidiabetic activity of a self-fermented Ariṣṭa preparation (DB-
Amitabha Dey, Satyajyoti Kanjilal, Rajarshi Biswas, Anjan Adhikari, Satyabrata Mohapatra, Deepa Gandhi, Bibhuti Nath Bhatt, Shiladitya Choudhuri, Pallabi Chakraborty, Tapas Kumar Sur, Avinash Narwaria, Chandra Kant Katiyar   +11 more
doaj   +1 more source