Results 61 to 70 of about 122,773 (309)

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Isolation of Bioactive Compounds from Calicotome villosa Stems

Molecules, 2018
A phenylethanoid, two steroids, a flavone glucoside and a chalcone have been isolated for the first time from the stems of Calicotome villosa together with a previously isolated flavone glucoside.
Josiane Alhage, Hoda Elbitar, Samir Taha, Jean-Paul Guegan, Zeina Dassouki, Thomas Vives, Thierry Benvegnu   +6 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Facts about type 2 diabetes mellitus and its control in Misan Governorate. Single-center experience [PDF]

The Medical Journal of Basrah University, 2018
Background: Diabetes mellitus is a metabolic disease that can affect every system of the body particularly if it is not controlled for long period of time. Complications of diabetes can be halted or prevented by good metabolic control.
Yaseen Yaseen, Jabbar Atyia
doaj   +1 more source

Traditional antidiabetic plants from Indonesia [PDF]

, 2020
Background: Indonesia with its widely varied geographical features is rich with knowledge and practice in the utilization of plants for maintaining health and treating diseases, including for diabetes mellitus.
Budipramana, Krisyanti, Hartanti, Dwi
core  

Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium‐glucose cotransporter 2 inhibitor users

British Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le, Dilsad Simay Peker, Lukas Frederic Westphal, Nikolai Brun, Christine Erikstrup Hallgreen, Morten Andersen   +5 more
wiley   +1 more source

Effect of Pleurotus fossulatus Aqueous Extract on Biochemical Properties of Liver and Kidney in Streptozotocin-Induced Diabetic Rat

Diabetes, Metabolic Syndrome and Obesity, 2020
Sushil Dubey, Chandrabhan Yadav, Anand Bajpeyee, Mohan P Singh Centre of Biotechnology, University of Allahabad, Prayagraj, Uttar Pradesh, IndiaCorrespondence: Mohan P SinghCoordinator, Centre of Biotechnology Institute of Interdisciplinary Studies (IIDS)
Dubey S, Yadav C, Bajpeyee A, Singh MP
doaj  

Antioxidant activity of pleurotus species and antidiabetic activity of pleurotus citrinopileatus (singer) / Rushitha Sadasevevam [PDF]

, 2011
The genus Pleurotus comprises some of the most popular edible mushrooms due to their favourable organoleptic and medicinal properties, vigorous growth and undemanding cultivation conditions. Pleurotus species contain a variety of secondary metabolites
Sadasevevam, Rushitha
core  

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Synthesis and biological evaluation of stilbene derivatives coupled to NO donors as potential antidiabetic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The work is focused on the design of drugs that prevent and treat diabetes and its complications. A novel class of stilbene derivatives were prepared by coupling NO donors of alkyl nitrate and were fully characterised by NMR and other techniques.
Bing Wang, Teng Liu, Zhongyu Wu, Lei Zhang, Jie Sun, Xiaojing Wang   +5 more
doaj   +1 more source