Results 51 to 60 of about 122,773 (309)

Pharmacogenetics of Antidiabetic Drugs

, 2018
Pharmacogenetic studies of antidiabetic drugs have so far focused largely on response to metformin, which is the first-line therapy for treatment of type 2 diabetes (T2D). The first studies of metformin pharmacogenetics were focused on candidate genes that were implicated in metformin pharmacokinetics and transport.
Srinivasan, Shylaja, Giacomini, Kathleen, Yee, Sook Wah   +2 more
openaire   +4 more sources

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Alpha-Glucosidase Inhibition and Hypoglycemic Activities of Sweitenia mahagoni Seed Extract

Hayati Journal of Biosciences, 2015
Inhibition of α-glucosidase and hypoglycemic activity are two effects commonly used to identify bioactive compounds with potential to treat diabetes.
TUTIK WRESDIYATI, SITI SA'DIAH, ADI WINARTO, VENNY FEBRIYANI   +3 more
doaj   +1 more source

Exploring potential antidiabetic and anti-inflammatory flavonoids from Euphorbia humifusa with an integrated strategy

Frontiers in Pharmacology, 2022
E. humifusa Willd, a monoecious annual plant, native to Eastern Asia, has been traditionally attributed to the treatment and prevention of miscellaneous diseases, including diabetes mellitus and its associated complications.
Tojofaniry Fabien Rakotondrabe, Tojofaniry Fabien Rakotondrabe, Tojofaniry Fabien Rakotondrabe, Minxia Fan, Minxia Fan, Minxia Fan, Mingquan Guo, Mingquan Guo, Mingquan Guo, Mingquan Guo   +9 more
doaj   +1 more source

Antidiabetic Plants Volume 3

, 2023
Indian culture & indigenous practises are based on nature & health care systems. A famous proverb defines it as there is not a single alphabet which is not a mantra: there is not a single plant which is not a medicine. Urbanization and metallic lifestyle
Vikas Tailor Anuradha Das Kadambini Das Rani Runam Ramadevi Devarakonda SK Sahanawaz Alam
core   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Antidiabetic Activities of 80% Methanol Extract and Solvent Fractions of Verbascum Sinaiticum Benth (Scrophulariaceae) Leaves in Mice

Journal of Experimental Pharmacology, 2023
Beyene Dereje,1 Aschalew Nardos,2 Jemal Abdela,3 Lidet Terefe,2 Melese Arega,4 Terfo Mikre Yilma,5 Tilahun Tesfaye6 1Department of Pharmacology, School of Medicine, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia ...
Dereje B, Nardos A, Abdela J, Terefe L, Arega M, Yilma TM, Tesfaye T   +6 more
doaj  

In silico study of the active compounds in bitter melon (Momordica charantia L) as antidiabetic medication [PDF]

Pharmaciana, 2018
Antidiabetic are many drugs available in the market, but most medications have side effects that are relatively high and cause toxicity, so it needs tobe develoved search of new drug compounds were more potent drugs with side effects as low.
Ruswanto Ruswanto, Richa Mardianingrum, Tresna Lestari, Tita Nofianti, Lilis Tuslinah, Dudi Nurmalik   +5 more
doaj   +1 more source

Solubility of Corosolic Acid in Supercritical Carbon Dioxide and Its Representation Using Density-Based Correlations [PDF]

, 2011
The solid solubilities of 2R,3β-dihydroxyurs-12-en-28-oic acid (corosolic acid) in supercritical carbon dioxide (SCCO2) have been measured using a dynamic method at (308.15, 313.15, 323.15, and 333.15) K over a pressure range of (8 to 30) MPa.
Andri C. Kumoro, Kumoro, A.C.
core   +1 more source