Results 31 to 40 of about 134,759 (289)

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Special Thai Oolong Tea: Chemical Profile and In Vitro Antidiabetic Activities

Frontiers in Pharmacology, 2022
Special Thai oolong tea is oolong tea (Camellia sinensis (L.) Kuntze) steamed with selected Thai botanical drugs. Oolong tea steamed with ginger (Zingiber officinale), lemongrass (Cymbopogon citratus), and celery (Anathallis graveolens L.) is called ...
Narawadee Rujanapun, Wuttichai Jaidee, Thidarat Duangyod, Thidarat Duangyod, Pravaree Phuneerub, Pravaree Phuneerub, Napassawan Paojumroom, Tharakorn Maneerat, Tharakorn Maneerat, Chuchawal Pringpuangkeo, Salfarina Ramli, Salfarina Ramli, Rawiwan Charoensup, Rawiwan Charoensup   +13 more
doaj   +1 more source

Quinces (Cydonia oblonga, Chaenomeles sp., and Pseudocydonia sinensis) as Medicinal Fruits of the Rosaceae Family: Current State of Knowledge on Properties and Use

Antioxidants
In recent years, the evaluation of many plant-derived compounds as potential new drugs or functional foods has become an active research topic. The morphological characteristics of quinces of the genera Cydonia sp., Chaenomeles sp., and Pseuocydonia sp ...
Anna Kostecka-Gugała
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evaluation of In Vitro Pharmacological Activities and HRLC-MS Based Profiling of Phlogacanthus jenkinsii C. B. Clarke

Journal of Pharmacopuncture
Objectives: Phlogacanthus jenkinsii is an ethnomedicinal plant used by the people of the North East Region of India to manage various health issues including diabetes and rheumatism. The present study examines the total phenolic and flavonoid content, in
Sajidul Hoque Ansari, Saikat Sen
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent

Journal of Pharmacy
This review provides a comprehensive exploration of the Psychotria species, a genus of plants known for their medicinal properties and traditional uses.
Sharifah Nurul Akilah Syed Mohamad, Alfi Khatib, Siti Zaiton Mat Soád, Qamar Uddin Ahmed, Zalikha Ibrahim   +4 more
doaj   +1 more source

Antidiabetic and Synergistic Effects Study of Anthocyanin Fraction from Berberis integerrima Fruit on Streptozotocin-Induced Diabetic Rats Model [PDF]

Trends in Pharmaceutical Sciences, 2016
Introduction: Diabetes mellitus is a complex endocrine disorder. There is serious attempt to realize antidiabetic compound from natural sources to use with other drugs for reduction of diabetes complication.  Materials and Methods: Present study is based
Zahra Sabahi, Mohammad Javad Khoshnood-Mansoorkhani, Solmaz Rahmani Namadi, Mahmoodreza Moein   +3 more
doaj  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Controlled Release of Pyrimidine Compound Using Polymeric Coated ZIF-8 Metal-Organic Framework as Glucagon-Like Peptide-1 Receptor Agonist Carrier

Molecules, 2020
This work demonstrates synthetic strategies for the incorporation of a synthesized pyrimidine glucagon-like peptide-1 (GLP-1) agonist into alginate-coated ZIF-8.
Shaikha S. AlNeyadi, Naheed Amir, Mohammad A. Ghattas, Noor Atatreh, Shaikha S. Alketbi, Ruba Al Ajeil, Abdu Adem   +6 more
doaj   +1 more source