Results 61 to 70 of about 7,199 (273)

Guidelines for the Diagnosis and Treatment of Advanced Breast Cancer in China (2024 Edition)

open access: yesCancer Innovation, Volume 4, Issue 6, December 2025.
“The core objective of this guideline is to personalize the management of advanced breast cancer through molecular subtyping, optimizing the balance between survival and quality of life. We integrate recent evidence‐based advances and underscore the essential roles of multidisciplinary collaboration and management of patient‐reported outcomes (PROs ...
Breast Cancer Expert Committee of the National Quality Control Center for Cancer   +2 more
wiley   +1 more source

Discovery of the Postcoital Contraceptive Effect of Rhus pentaphylla in a Study of Acute, Subchronic, and Neurodevelopmental Toxicity of Ethanolic Leaf Extract

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT In the present study, the acute, subchronic, and neurodevelopmental toxicity of Rhus pentaphylla, a Moroccan medicinal plant, was investigated in Swiss albino mice. HPLC analysis showed the presence of phenolic compounds with rutin as the principal component.
Fatimazahra Agouram   +4 more
wiley   +1 more source

A Comparison of Pretravel Health Care, Travel-Related Exposures, and Illnesses among Pediatric and Adult U.S. Military Beneficiaries.

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2019
We evaluated differences in pretravel care, exposures, and illnesses among pediatric and adult travelers, using a prospective, observational cohort.
David P. Ashley   +24 more
semanticscholar   +1 more source

Resource Utilization of Peanut Shells: Nutritional Characteristics, Regulation of Antinutritional Factors, and Application Potential in Livestock and Poultry Production

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
The article reviews the potential of peanut hulls as livestock feed, highlighting their nutritional components, processing methods, and challenges. Despite being rich in fiber, minerals, and bioactive substances, peanut hulls contain anti‐nutritional factors.
Mengen Zhang   +6 more
wiley   +1 more source

Loperamide: From antidiarrheal to analgesic

open access: yesJournal of Opioid Management, 2013
Loperamide, an antidiarrheal drug has been observed to produce analgesia in animal models of pain. However, the exact mechanism underlying loperamide analgesia needs further studies.
openaire   +3 more sources

Antidiarrheal activity of α-terpineol in mice

open access: yesBiomedicine & Pharmacotherapy, 2019
Diarrhea is one of the leading causes of infant death in the world accounting for high child mortality rate. It is also present in different pathophysiologies related to several etiological agents. The aim of this study is to investigate the antidiarrheal effect of α -Terpineol (α-TPN) in different diarrhea models in rodents.
Polyanna dos Santos Negreiros   +9 more
openaire   +2 more sources

Hibiscus rosa‐sinensis: A Multifunctional Flower Bridging Nutrition, Medicine, and Molecular Therapeutics

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
H. rosa‐sinensis bioactives modulate oxidative and inflammatory pathways. Myricetin and rutin show strong α‐glucosidase and SOD binding affinity. Exhibits safe, multifunctional use in health, food and nutraceuticals. ABSTRACT Hibiscus rosa‐sinensis, commonly known as the shoe flower, thrives in tropical and subtropical regions across South China, Asia,
Hassan Raza   +6 more
wiley   +1 more source

Chinese Patent Medicine Ameliorate Ulcerative Colitis in Mice by Restoring the Th17/Treg Balance

open access: yesGut Medicine, Volume 1, Issue 1, Page 30-44, December 2025.
ABSTRACT Background and Objective In China, Weichang'an Pill (WCAP) is a drug marketed for mild and moderate active ulcerative colitis (UC) but its mechanism is unknown. In the present study, the anti‐inflammatory mechanism of WCAP was investigated. Methods Dextran sulfate sodium (DSS) was used to induce UC in mice, which were divided into 4 groups (n =
Tao Zhang   +6 more
wiley   +1 more source

Saliva as a TDM Matrix and Its Application in the Model‐Informed Precision Dosing

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1650-1660, December 2025.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

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