Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways. Overexposure to epinephrine inactivates adenylate-cyclase,a causal pathway for stress-pathologies [PDF]
Incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (Mg2+) is required for the neurotransmitter activatory response of Adenylate Cyclase [ATP pyrophosphate-lyase (cyclizing), (EC 4.6.1.1)], AC.An Mg2+-dependent response to the activatory effects of adrenaline, and ...
arxiv
Astrocytic NMDA Receptors Modulate the Dynamics of Continuous Attractors [PDF]
Neuronal networking supports complex brain functions, with neurotransmitters facilitating communication through chemical synapses. The release probability of neurotransmitters varies and is influenced by pre-synaptic neuronal activity. Recent findings suggest that blocking astrocytic N-Methyl-D-Aspartate (NMDA) receptors reduces this variation. However,
arxiv
Tolvaptan is successful in treating inappropriate antidiuretic hormone secretion in infants
Daniela Marx-Berger+6 more
semanticscholar +1 more source
Leveraging 13C NMR spectroscopic data derived from SMILES to predict the functionality of small biomolecules by machine learning: a case study on human Dopamine D1 receptor antagonists [PDF]
This study contributes to ongoing research which aims to predict small biomolecule functionality using Carbon-13 Nuclear Magnetic Resonance ($^{13}$C NMR) spectrum data and machine learning (ML). The approach was demonstrated using a bioassay on human dopamine D1 receptor antagonists.
arxiv
Comparative analysis of computational approaches for predicting Transthyretin transcription activators and human dopamine D1 receptor antagonists [PDF]
The study expands the application of scikit-learn-based machine learning (ML) to the prediction of small biomolecule functionalities based on Carbon 13 isotope (13C) NMR spectroscopy data derived from Simplified Molecular Input Line Entry System (SMILES) notations.
arxiv
ICI-RS 2015 : is a better understanding of sleep the key in managing nocturia? [PDF]
Cherian, Jerald+8 more
core +2 more sources
Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone. [PDF]
Yamamoto H+8 more
europepmc +1 more source
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) in Chronic Respiratory Diseases: A Comprehensive Review. [PDF]
Al Zaman K+5 more
europepmc +1 more source