Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications. [PDF]
Alcohol Clin Exp Res (Hoboken)The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Molina PE, Simon L.
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Vasopressin-2 receptor antagonists: potent but potentially dangerous drugs for the treatment of severe hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion [PDF]
Endocrine Abstracts, 2015 Vikki Tilliridou +2 more
openaire +2 more sources
Metabolic effects of vasopressin in pathophysiology of diabetic kidney disease
Frontiers in Endocrinology, 2023 The diabetic kidney disease (DKD) is the major cause of the chronic kidney disease (CKD). Enhanced plasma vasopressin (VP) levels have been associated with the pathophysiology of DKD and CKD.
Svetlana Lebedeva +7 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 In addition to long-term regulation of blood pressure (BP), in the kidney resides the initial trigger for hypertension development due to an altered capacity to excrete sodium and water.
Ignazio Verzicco +17 more
doaj +1 more source
Kidney Medicine, 2020 Rationale & Objective: Euvolemic hyponatremia often occurs due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Vasopressin 2 receptor antagonists may be used to treat SIADH.
Ramy M. Hanna +10 more
doaj +1 more source
UNDULY ENHANCED RESPONSE TO TOLVAPTAN IN A WOMAN SHOWING SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION: AN INVESTIGATION OF POSSIBLE CAUSES [PDF]
, 2017 Objective: To investigate possible causes of an excessive response to tolvaptan in a woman with syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Lanzellotti, Davide +4 more
core +1 more source
Hyponatremia in Liver Cirrhosis
The Korean Journal of Gastroenterology, 2018 Hyponatremia is a commonly observed complication that is related to hypoalbuminemia and portal hypertension in patients with advanced liver cirrhosis. Hyponatremia in patients with liver cirrhosis is mostly dilutional hyponatremia and is defined when the
Cheolmin Jang, Young Kul Jung
doaj +1 more source
Angiotensin-(1-7) increases osmotic water permeability in isolated toad skin [PDF]
, 2000 Angiotensin-(1-7) (Ang-(1-7)) increased osmotic water permeability in the isolated toad skin, a tissue with functional properties similar to those of the distal mammalian nephron. Concentrations of 0.1 to 10 μM were effective, with a peak at 20 min. This
Coviello, Alfredo +3 more
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Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]
, 2013 Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P +4 more
core +2 more sources
Resolution of severe hyponatraemia is associated with improved survival in patients with cancer [PDF]
, 2015 © Balachandran et al.Background: Hyponatraemia is a common finding in patients with cancer, and has been shown to be associated with poor prognosis in different settings.
Balachandran, K +4 more
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