Results 51 to 60 of about 4,971 (132)

Analyzing the adverse events of NK-1 receptor antagonists: a pharmacovigilance study from the FAERS database

Scientific Reports
Background NK-1 receptor antagonists (NK-1RAs) are proven to be successful in preventing chemotherapy-induced nausea and vomiting (CINV). The safety profile of NK-1RAs has not been systematically analyzed in the real world.
Hong Pan, Xiang Shi, Yiguo Jiang, Jiaqiang Wu, Li Shen   +4 more
doaj   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, Volume 14, Issue 13, May 16, 2025.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Altered agonist sensitivity of a mutant V2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus. [PDF]

, 2014
Loss of function mutations of the type 2 vasopressin receptor (V2R) in kidney can lead to nephrogenic diabetes insipidus (NDI). We studied a previously described, but uncharacterized mutation of V2R (N321K missense mutation) of an NDI patient.
Balla, András, Erdélyi, László Sándor, Hunyady, László, Patócs, Attila, Tóth, Miklós, Várnai, Péter   +5 more
core   +1 more source

Recent Advances in Betaine: Extraction, Identification, and Bioactive Functions in Human Health

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
Betaine exhibits a range of biological activities, including antioxidant properties and the ability to enhance the preservation of fruits and vegetables post‐harvest. Betaine contributes positively to human health and is associated with various beneficial effects on well‐being.
Donglan Luo, Xiaogang Wang, Sen Cao, Liangjie Ba, Jianye Chen   +4 more
wiley   +1 more source

Conivaptan: a step forward in the treatment of hyponatremia? [PDF]

, 2008
Hyponatremia is one of the most common electrolyte abnormalities linked to adverse outcomes and increased mortality in hospitalized patients. While the differential diagnosis for hyponatremia is diverse, most cases stem from arginine vasopressin (AVP ...
Aung, May H, Hline, Su Su, Pham, Phuong-Chi T, Pham, Phuong-Mai T, Pham, Phuong-Thu T, Pham, Phuong-Truc T   +5 more
core   +2 more sources

Body fluids and salt metabolism - Part II [PDF]

, 2010
There is a high frequency of diarrhea and vomiting in childhood. As a consequence the focus of the present review is to recognize the different body fluid compartments, to clinically assess the degree of dehydration, to know how the equilibrium between ...
Bettinelli, Alberto, Bianchetti, Mario G, Fossali, Emilio F, Garzoni, Luca, Longoni, Laura, Milani, Gregorio P, Peruzzo, Mattia, Simonetti, Giacomo D   +7 more
core   +4 more sources

Utility and Safety of Tolvaptan in Cirrhotic Patients with Hyponatremia: a Prospective Cohort Study

Annals of Hepatology, 2017
Introduction and aim: Hyponatremia is common in patients with decompensated cirrhosis and is associated with increased mortality. Tolvaptan, a vasopressor V2 receptor antagonist, can increase free water excretion, but its efficacy and safety in cirrhotic
Ji-Dong Jia, Wen Xie, Hui-Guo Ding, Hua Mao, Hui Guo, Yonggang Li, Xiaojin Wang, Jie-Fei Wang, Wei Lu, Cheng-Zhong Li, Yimin Mao, Gui-Qiang Wang, Yue-qiu Gao, Bangmao Wang, Qin Zhang, Yan Ge, Vincent Wai-Sun Wong   +16 more
doaj  

Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis [PDF]

arXiv, 2023
Objective: We aimed to develop a meta-analytic model for evaluation of predictive biomarkers and targeted therapies, utilising data from digital sources when individual participant data (IPD) from randomised controlled trials (RCTs) are unavailable. Methods: A Bayesian network meta-regression model, combining aggregate data (AD) from RCTs and IPD ...
arxiv  

Haemato‐Urological Profile and Asymptomatic Urinary Tract Infection in Ghanaian Steady‐State Sickle Cell Disease Patients: A Case‐Control Study

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Due to the reduction in immunity caused by auto‐splenectomy and the consequent opsonic antibody shortage, patients with SCD are more susceptible to encapsulated organism infections, especially asymptomatic urinary tract infection (ASM‐UTI).
Stephen Twumasi, Richard Owusu Ansah, Samuel Essien‐Baidoo, Laud Anthony W. Basing, Alexander Yaw Debrah, Enoch Odame Anto, Allwell Adofo Ayirebi, Rebecca Asiamah‐Broni, Waldemer Attivor, Eric Twum Ameyaw, Gabriel Addai Manu, Edward Afriyie, Thomas Kwabena Gyampomah, Joseph Nkrumah Opoku, Prince Kwadwo Amoafo, Samuel Kelvin Owusu, Vincent Akwai, Matthew Talmang, Amos Mensah, Isaac Kusi‐Amponsah, Angela Opoku, Lilian Antwi Boateng   +21 more
wiley   +1 more source

FMO Interaction Energy between 17$β$-Estradiol, 17$α$-Estradiol and Human Estrogen Receptor $α$ [PDF]

arXiv, 2020
The estrogen receptor is a nuclear hormone receptor activated by the natural steroid hormone 17$\beta$-estradiol (E2). Fragment molecular orbital (FMO) calculations were performed which allowed us to obtain the interaction energy ($E_{int}$) between E2, 17$\alpha$-estradiol (17$\alpha$-E2) and the human estrogen receptor $\alpha$ ligand-binding domain.
arxiv