Results 61 to 70 of about 4,971 (132)

Global warming and obesity: External heat exposure as a modulator of energy balance

open access: yesFASEB BioAdvances, Volume 7, Issue 4, April 2025.
Core body temperature regulation can significantly influence metabolic processes to maintain energy balance. For example, geographic and environmental factors (global warming) can affect obesity rates and can be tracked along latitudinal boundaries.
Imani Muhammad   +3 more
wiley   +1 more source

The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation

open access: yesBiological Reviews, Volume 100, Issue 2, Page 647-671, April 2025.
ABSTRACT Arthropods have integrated digestive and renal systems, which function to acquire and maintain homeostatically the substances they require for survival. The cryptonephridial complex (CNC) is an evolutionary novelty in which the renal organs and gut have been dramatically reorganised. Parts of the renal or Malpighian tubules (MpTs) form a close
Robin Beaven, Barry Denholm
wiley   +1 more source

Association Between Atherogenic, Thrombogenic, and Lipophilic Indices and the Odds of Diabetic Nephropathy in Type 2 Diabetic Patients: A Case–Control Study

open access: yesFood Science &Nutrition, Volume 13, Issue 3, March 2025.
This is the first investigation that examined the association between atherogenic (IA), thrombogenic (IT), and lipophilic (LT) indices ‐as fat intake indicators‐ and diabetic nephropathy (DN). This study found Type 2 diabetes mellitus (T2DM) patients in the highest quartile of atherogenic, thrombogenic, and lipophilic indices had a greater likelihood ...
Behnood Abbasi   +2 more
wiley   +1 more source

Structure and dynamics of dynorphin peptide and its receptor [PDF]

open access: yesarXiv, 2019
Dynorphin is a neuropeptide involved in pain, addiction and mood regulation. It exerts its activity by binding to the kappa opioid receptor (KOP) which belongs to the large family of G-protein coupled receptors. The dynorphin peptide was discovered in 1975, while its receptor was cloned in 1993.
arxiv  

In vitro and in vivo evaluation of the cyclophosphamide effect along with oncolytic Newcastle disease virus (NDV): An animal preclinical research

open access: yesMalignancy Spectrum, Volume 2, Issue 1, Page 13-25, March 2025.
This article explores combining Newcastle disease virus (NDV) with chemotherapy for treating breast cancer. Results show promising effects, including tumor suppression and improved patient prognosis without harming healthy tissues. The study suggests that NDV combined with chemotherapy could be a valuable treatment option, highlighting its potential ...
Mohammad Reza Foroughi‐Gilvaee   +3 more
wiley   +1 more source

V2 Receptor Antagonist; Tolvaptan [PDF]

open access: yes, 2011
Hyponatremia is the most common electrolyte disorder in hospitalized patients. Many studies documented that it was related to increased morbidity and mortality in patients with congestive heart failure, liver cirrhosis, and neurologic diseases.
Berl   +18 more
core   +3 more sources

Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]

open access: yesarXiv, 2023
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv  

Sleep‐Related Breathing Disorders and Lower Urinary Tract Dysfunction in Children and Adolescents: A Scoping Review

open access: yesNeurourology and Urodynamics, Volume 44, Issue 2, Page 464-479, February 2025.
ABSTRACT Aims Sleep disordered breathing (SDB), lower urinary tract dysfunction (LUTD), and enuresis (NE) are common in children and adolescents and have serious consequences, especially on social and emotional development. Even though much is known about the association between SDB and NE among adults, the number of articles in children and ...
Maayke van Galen   +4 more
wiley   +1 more source

Peripheral oxytocin and vasopressin:Biomarkers of psychiatric disorders? A comprehensive systematic review and preliminary meta-analysis [PDF]

open access: yes, 2016
A large array of studies have investigated peripheral oxytocin (OT) and vasopressin (ADH) as potential biomarkers of psychiatric disorders, with highly conflicting and heterogenous findings. We searched Web of KnowledgeSM and Scopus® for English original
Cappucciati, Marco   +11 more
core   +1 more source

Genetic polymorphisms influencing antihypertensive drug responses

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 4, Page 929-950, February 2025.
Abstract Hypertension is a major contributor to cardiovascular disease and its associated morbidity and mortality. The low efficacy observed with some anti‐hypertensive therapies has been attributed partly to inter‐individual genetic variability. This paper reviews the major findings regarding these genetic variabilities that modulate responses to anti‐
Jana El Cheikh   +4 more
wiley   +1 more source

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