Results 61 to 70 of about 4,971 (132)
Global warming and obesity: External heat exposure as a modulator of energy balance
Core body temperature regulation can significantly influence metabolic processes to maintain energy balance. For example, geographic and environmental factors (global warming) can affect obesity rates and can be tracked along latitudinal boundaries.
Imani Muhammad+3 more
wiley +1 more source
The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation
ABSTRACT Arthropods have integrated digestive and renal systems, which function to acquire and maintain homeostatically the substances they require for survival. The cryptonephridial complex (CNC) is an evolutionary novelty in which the renal organs and gut have been dramatically reorganised. Parts of the renal or Malpighian tubules (MpTs) form a close
Robin Beaven, Barry Denholm
wiley +1 more source
This is the first investigation that examined the association between atherogenic (IA), thrombogenic (IT), and lipophilic (LT) indices ‐as fat intake indicators‐ and diabetic nephropathy (DN). This study found Type 2 diabetes mellitus (T2DM) patients in the highest quartile of atherogenic, thrombogenic, and lipophilic indices had a greater likelihood ...
Behnood Abbasi+2 more
wiley +1 more source
Structure and dynamics of dynorphin peptide and its receptor [PDF]
Dynorphin is a neuropeptide involved in pain, addiction and mood regulation. It exerts its activity by binding to the kappa opioid receptor (KOP) which belongs to the large family of G-protein coupled receptors. The dynorphin peptide was discovered in 1975, while its receptor was cloned in 1993.
arxiv
This article explores combining Newcastle disease virus (NDV) with chemotherapy for treating breast cancer. Results show promising effects, including tumor suppression and improved patient prognosis without harming healthy tissues. The study suggests that NDV combined with chemotherapy could be a valuable treatment option, highlighting its potential ...
Mohammad Reza Foroughi‐Gilvaee+3 more
wiley +1 more source
V2 Receptor Antagonist; Tolvaptan [PDF]
Hyponatremia is the most common electrolyte disorder in hospitalized patients. Many studies documented that it was related to increased morbidity and mortality in patients with congestive heart failure, liver cirrhosis, and neurologic diseases.
Berl+18 more
core +3 more sources
Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv
ABSTRACT Aims Sleep disordered breathing (SDB), lower urinary tract dysfunction (LUTD), and enuresis (NE) are common in children and adolescents and have serious consequences, especially on social and emotional development. Even though much is known about the association between SDB and NE among adults, the number of articles in children and ...
Maayke van Galen+4 more
wiley +1 more source
Peripheral oxytocin and vasopressin:Biomarkers of psychiatric disorders? A comprehensive systematic review and preliminary meta-analysis [PDF]
A large array of studies have investigated peripheral oxytocin (OT) and vasopressin (ADH) as potential biomarkers of psychiatric disorders, with highly conflicting and heterogenous findings. We searched Web of KnowledgeSM and Scopus® for English original
Cappucciati, Marco+11 more
core +1 more source
Genetic polymorphisms influencing antihypertensive drug responses
Abstract Hypertension is a major contributor to cardiovascular disease and its associated morbidity and mortality. The low efficacy observed with some anti‐hypertensive therapies has been attributed partly to inter‐individual genetic variability. This paper reviews the major findings regarding these genetic variabilities that modulate responses to anti‐
Jana El Cheikh+4 more
wiley +1 more source