Results 71 to 80 of about 4,971 (132)

Hyponatraemia [PDF]

open access: yes, 2013
Hyponatriämie ist die häufigste Elektrolytstörung bei hospitalisierten Patienten und stellt ein wichtiges klinisches und soziales Problem dar. Sie kann vor allem in akuten und schweren Fällen einen lebensbedrohenden Zustand darstellen und wurde mit ...
Peri, Alessandro
core   +1 more source

Scalable Production of Highly-Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor [PDF]

open access: yes, 2014
We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand binding. A variant of the receptor protein that provided chemical recognition was computationally redesigned to ...
arxiv   +1 more source

Hormonal Implications of SARS‐CoV‐2: A Review of Endocrine Disruptions

open access: yesScientifica, Volume 2025, Issue 1, 2025.
To improve medical care and rehabilitation algorithms for patients affected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), it is important to evaluate and summarize the available data on the effect of coronavirus infection (COVID‐19) on the endocrine system.
Aliya Yskak   +10 more
wiley   +1 more source

Rapid divergence of the ecdysone receptor in Diptera and Lepidoptera suggests coevolution between ECR and USP-RXR [PDF]

open access: yesMolecular Biology and Evolution 4, 20 (2003) 541-553, 2008
Ecdysteroid hormones are major regulators in reproduction and development of insects, including larval molts and metamorphosis. The functional ecdysone receptor is a heterodimer of ECR (NR1H1) and USP-RXR (NR2B4), which is the orthologue of vertebrate retinoid X receptors (RXR alpha, beta, gamma).
arxiv  

Inclusion of Enclosed Hydration Effects in the Binding Free Energy Estimation of Dopamine D3 Receptor Complexes [PDF]

open access: yes, 2019
Confined hydration and conformational flexibility are some of the challenges encountered for the rational design of selective antagonists of G-protein coupled receptors. We present a set of C3-substituted (-)-stepholidine derivatives as potent binders of the dopamine D3 receptor.
arxiv   +1 more source

Is hyponatremia caused by Chinese herbal medicine a myth? A scoping review and a review of local data in Hong Kong

open access: yesHong Kong Journal of Emergency Medicine, Volume 31, Issue 6, Page 321-330, December 2024.
Abstract Introduction Hyponatremia is one of the commonly inquired adverse effects related to Chinese herbal medicine (CHM) received by the Hong Kong Poison Information Center. However, it has never been investigated or reviewed systemically. The purpose of this review is to look into the relationship between CHM and hyponatremia.
Wu Ping   +3 more
wiley   +1 more source

Tolvaptan and its potential in the treatment of hyponatremia [PDF]

open access: yes, 2008
Tolvaptan is a selective arginine vasopressin (AVP) V2 receptor blocker used to induce free water diuresis in the treatment of euvolemic or hypervolemic hyponatremia.
Dixon, Megan B, Lien, Y Howard
core   +2 more sources

Antidiuretic Effects of the Endothelin Receptor Antagonist Avosentan [PDF]

open access: yes, 2012
Several clinical studies have investigated the potential benefits of endothelin receptor antagonism in chronic pathologies such as diabetic kidney disease.
Christian eZaugg   +8 more
core   +3 more sources

Neuralgic amyotrophy presentation of acute intermittent porphyria: A case report

open access: yesJournal of the Peripheral Nervous System, Volume 29, Issue 4, Page 567-569, December 2024.
Abstract Background and Aims Porphyrias are inherited metabolic disorders caused by mutations in genes encoding enzymes involved in the heme biosynthetic pathway, leading to the accumulation of heme precursors. Acute hepatic porphyrias (AHP), including acute intermittent porphyria (AIP), can present with predominant peripheral neurological ...
Julian Theuriet   +4 more
wiley   +1 more source

Functional Characterization of the Arginine Vasotocin 4 Receptor (VT4R) in Sensory Circumventricular Organs of the Chicken Gallus gallus [PDF]

open access: yes, 2014
Past studies have shown that the avian vasotocin 4 receptor (VT4R), homologous to the mammalian arginine vasopressin receptor 1a (V1aR/AVPR1A) is involved in immobilization stress.
Aman, Nguiessan Alphonse
core   +2 more sources

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