Results 21 to 30 of about 30,801 (283)

SYNTHESIS OF TETRAKIS-N,N,N-TRIMETHYLAMMONIUMMETHYL-C-3,4-DIMETHOXYPHENYLCALIX[4]RESORCINARENE IODIDE BASED VANILLIN AND ITS ANTIDOTE ACTIVITY FOR CHROMIUM(VI) INTOXICATION

open access: yesIndonesian Journal of Chemistry, 2013
A research has been conducted to synthesize tetrakis-N,N,N-trimethylammoniummethyl-C-3,4-dimethoxyphenylcalix[4]resorcinarene iodide from vanillin and investigate its antidote capability for Cr(VI) intoxication.
Suryadi Budi Utomo   +3 more
doaj   +1 more source

Case Report: Serum methotrexate monitoring by immunoassay: confusion by by-product, confusion by antidote

open access: yesFrontiers in Oncology, 2023
Methotrexate is a commonly used agent in the treatment of many malignancies and rheumatologic/inflammatory diseases. Working by inhibiting dihydrofolate reductase and thereby preventing eventual formation of tetrahydrofolate, methotrexate inhibits ...
Aditya Sharma   +3 more
doaj   +1 more source

La corruption et son antidote dans les œuvres de Tijan M. Sallah, Tanure Ojaide et Tunde Omobawale

open access: yesFlamme, 2021
Le présent travail a pour objectif d’analyser combien la corruption, ses causes et ses effets imprègnent l’espace ouest-africain en particulier et l’Afrique en général. Le thème de la corruption n’est certes pas une nouveauté, mais son ampleur se ressent
Lice John Mendy
doaj   +1 more source

Design strategy of antidote sequence for bivalent aptamer: Rapid neutralization of high‐anticoagulant thrombin‐binding bivalent DNA aptamer‐linked M08 with HD22

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Bivalent thrombin‐binding aptamers (TBAs) have great potential for the treatment of thrombosis because they exhibit high anticoagulant activity, and their complementary single‐stranded DNA (ssDNA) sequences work as an antidote.
Toru Yoshitomi   +3 more
doaj   +1 more source

Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Venom

open access: yesToxins, 2018
There is a clear, unmet need for effective, lightweight, shelf-stable and economical snakebite envenoming therapies that can be given rapidly after the time of a snake’s bite and as adjuncts to antivenom therapies in the hospital setting. The sPLA2
Matthew R. Lewin   +6 more
doaj   +1 more source

Application of Activated Carbon Derived from Seed Shells of Jatropha curcas for Decontamination of Zearalenone Mycotoxin

open access: yesFrontiers in Pharmacology, 2017
In the present study, activated carbon (AC) was derived from seed shells of Jatropha curcas and applied to decontaminate the zearalenone (ZEA) mycotoxin. The AC of J.
Naveen K. Kalagatur   +7 more
doaj   +1 more source

Pharmacologic and Clinical Considerations of Nalmefene, a Long Duration Opioid Antagonist, in Opioid Overdose

open access: yesPsychiatry International, 2021
Opioid use disorder is a well-established and growing problem in the United States. It is responsible for both psychosocial and physical damage to the affected individuals with a significant mortality rate.
Amber N. Edinoff   +9 more
doaj   +1 more source

Ubiquitination-mediated Golgi-to-endosome sorting determines the toxin-antidote duality of fission yeast wtf meiotic drivers

open access: yesNature Communications, 2023
Killer meiotic drivers (KMDs) skew allele transmission in their favor by killing meiotic progeny not inheriting the driver allele. Despite their widespread presence in eukaryotes, the molecular mechanisms behind their selfish behavior are poorly ...
Jin-Xin Zheng   +9 more
doaj   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng   +6 more
wiley   +1 more source

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