Results 31 to 40 of about 61,897 (362)

Availability of Essential Antidotes and the Role of Community Pharmacists in the Management of Acute Poisoning: A Cross-Sectional Study in Ethiopia

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2022
Background Morbidity and mortality related to acute poisoning is a major public health issue in both developing and developed countries. Community pharmacists have a crucial role in ensuring drug availability, increasing drug safety, counseling patients,
Zemene Demelash Kifle MSc, Dawit Kumilachew Yimenu, Chilot Abiyu Demeke, Asmamaw Emagn Kasahun, Ebrahim Abdela Siraj, Adane Yehualaw Wendalem, Zegaye Agmassie Bazezew, Abebe Basazn Mekuria   +7 more
doaj   +1 more source

Guidelines for the management of extravasation [PDF]

Journal of Educational Evaluation for Health Professions, 2020
The purpose of these practice guidelines is to offer and share strategies for preventing extravasation and measures for handling drugs known to cause tissue necrosis, which may occur even with the most skilled experts at intravenous (IV) injection ...
Jung Tae Kim, Jeong Yun Park, Hyun Jung Lee, Young Ju Cheon   +3 more
doaj   +1 more source

How we treat bleeding associated with direct oral anticoagulants [PDF]

, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +4 more
core   +1 more source

Specific Antidotes for Direct Oral Anticoagulants in Life-Threatening Bleeding

Рациональная фармакотерапия в кардиологии, 2019
Review presents data on medicines from the new group of cardiovascular drugs, direct oral anticoagulants (DOACs) inhibitors, as antidotes for DOAC when stopping life-threatening bleeding.
A. B. Sumarokov, L. I. Buryachkovskaya, N. V. Lomakin   +2 more
doaj   +1 more source

Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells

Arhiv za Higijenu Rada i Toksikologiju, 2022
Current research has shown that several imidazolium and chlorinated bispyridinium oximes are cytotoxic and activate different mechanisms or types of cell death.
Zandona Antonio, Zorbaz Tamara, Miš Katarina, Pirkmajer Sergej, Katalinić Maja   +4 more
doaj   +1 more source

Optimal Resource Allocation for Network Protection Against Spreading Processes [PDF]

, 2013
We study the problem of containing spreading processes in arbitrary directed networks by distributing protection resources throughout the nodes of the network.
Enyioha, Chinwendu, Jadbabaie, Ali, Pappas, George, Preciado, Victor M., Zargham, Michael   +4 more
core   +3 more sources

Autoinjector device for rapid administration of drugs and antidotes in emergency situations and in mass casualty management

Journal of International Medical Research, 2020
There are several situations such as medical emergencies and incidents involving mass casualties where drugs and antidotes have to be administered immediately along with other first aid at the site of the event. Self-administration by the affected person
R. Vijayaraghavan
semanticscholar   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Antidote availability in the municipality of Campinas, São Paulo, Brazil

São Paulo Medical Journal, 2017
CONTEXT AND OBJECTIVE: The lack of availability of antidotes in emergency services is a worldwide concern. The aim of the present study was to evaluate the availability of antidotes used for treating poisoning in Campinas (SP).
Luciane Cristina Rodrigues Fernandes, Taís Freire Galvão, Adriana Safioti Toledo Ricardi, Eduardo Mello De Capitani, Stephen Hyslop, Fábio Bucaretchi   +5 more
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
doaj   +1 more source