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Clinical Applications of Substance P (Neurokinin-1 Receptor) Antagonist in Canine Medicine [PDF]

open access: yesArchives of Razi Institute, 2021
Substance P binds to the Neurokinin-1 (NK-1) receptors found in the emetic center of the central nervous system (CNS) to induce emesis. Maropitant is a selective NK-1 receptor antagonist that inhibits the binding of substance P to NK-1 receptors and is ...
K Sharun   +7 more
doaj   +1 more source

Use of Coca-Cola drinks in gastric pathology in pediatric patients [PDF]

open access: yesRomanian Journal of Pediatrics, 2020
Facing us the relatively frequent tendency of many people – medical professionals or not – to administer Coca-Colatype carbonated beverages in the case of nausea-type gastric symptoms or vomiting in pediatric or adult patients, we have tried to ...
Cristina Munteanu
doaj   +1 more source

Utilizarea băuturilor de tip Coca-Cola în patologia gastrică la pacienţii pediatrici [PDF]

open access: yesRomanian Journal of Pediatrics, 2020
În faţa tendinţei relativ frecvente a multor persoane – cadre medicale sau nu – de a administra băuturi carbogazoase de tipul Coca-Cola în cazul unor simptome gastrice de tip greaţă sau vărsături la pacienţii pediatrici sau adulţi, am încercat să ...
Cristina Munteanu
doaj   +1 more source

Economic Value of Fosaprepitant-Containing Regimen in the Prevention of Chemotherapy-Induced Nausea and Vomiting in China: Cost-Effectiveness and Budget Impact Analysis

open access: yesFrontiers in Public Health, 2022
ObjectiveThe purpose of this study was to evaluate the cost-effectiveness and budget impact of fosaprepitant (FosAPR)-containing regimen for the prevention of chemotherapy-induced nausea and vomiting (CINV) among patients receiving high emetogenic ...
Xinglu Xu   +7 more
doaj   +1 more source

Comparative Study of Ondansetron and Palonosetron for Prevention of Nausea and Vomiting Following Upper Abdominal Surgeries under General Anaesthesia: A Randomised Control Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Postoperative Nausea and Vomiting (PONV) is a common entity following surgical procedure. It may result into serious complication like aspiration of gastric contents, prolonged recovery period.
Deepak Premnarayan Gupta, Vijay Chandak
doaj   +1 more source

Chemotherapy-Induced Nausea and Vomiting (CINV) with GI Cancer Chemotherapy: Do We Need CINV Risk Score Over and Above Antiemetic Guidelines in Prescribing Antiemetic Regime?

open access: yesSouth Asian Journal of Cancer, 2020
Background Various predictive models have been developed which incorporates patient risk factors into the selection of optimal antiemetic therapy, one of which is chemotherapy-induced nausea and vomiting (CINV) risk scoring system developed by ...
Anita D’Souza   +8 more
doaj   +1 more source

Is PONV still a problem in pediatric surgery: a prospective study of what children tell us

open access: yesFrontiers in Pediatrics, 2023
BackgroundPostoperative nausea and vomiting (PONV) is an unpleasant complication after surgery that commonly co-occurs with pain. Considering the high prevalence among pediatric patients, it is important to explore the main risk factors leading to PONV ...
Brigitte Messerer   +8 more
doaj   +1 more source

Treatment with Oral Ondansetron for Ultramarathon-Associated Nausea: The TOO FUN Study

open access: yesSports, 2021
Nausea and vomiting are common for runners during ultramarathons and often contribute to non-finishes. We aimed to determine the efficacy of ondansetron, a commonly used antiemetic, to treat nausea and vomiting in runners during an ultramarathon. Runners
Andrew V. Pasternak   +4 more
doaj   +1 more source

Assessment of Quercetin Antiemetic Properties: In Vivo and In Silico Investigations on Receptor Binding Affinity and Synergistic Effects

open access: yesPlants, 2023
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has demonstrated a diverse range of biological activities. The primary objective of the current study is to assess the potential antiemetic properties of QUA using an in vivo and ...
Raihan Chowdhury   +7 more
doaj   +1 more source

Evidence for Bell-Shaped Dose-Response Emetic Effects of Temsirolimus and Analogs: The Broad-Spectrum Antiemetic Efficacy of a Large Dose of Temsirolimus Against Diverse Emetogens in the Least Shrew (Cryptotis parva)

open access: yesFrontiers in Pharmacology, 2022
Temsirolimus is a prodrug form of sirolimus (rapamycin). With its analogs (everolimus, ridaforolimus, and rapamycin), it forms a group of anticancer agents that block the activity of one of the two mammalian targets of rapamycin (mTOR) complexes, mTORC1.
Louiza Belkacemi   +2 more
doaj   +1 more source

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