Results 71 to 80 of about 37,620 (268)

Adherence to antiepileptic drugs among children attending a tertiary health unit in a low resource setting

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: Epilepsy is one of the neglected and highly stigmatised diseases, yet it is very common affecting about 70 million people worldwide. In Uganda, the estimated prevalence of epilepsy is 13% with about 156 new cases per 100,000 people per year.
Rose Nazziwa   +4 more
doaj   +1 more source

Movement Disorders Induced by Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2007
The prevalence and risk factors for the development of movement disorders, mainly parkinsonism and postural tremor, were analyzed in 201 adults (>18 years, mean 40 years) treated with valproate and newer antiepileptic drugs (AED) at the Epilepsy Clinic ...
J Gordon Millichap
doaj   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen   +4 more
wiley   +1 more source

Status Epilepticus Induced by Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2006
Adolescent and adult patients with idiopathic generalized epilepsy (IGE) who developed paradoxical video-EEG documented status epilepticus (SE) precipitated by inappropriate antiepileptic drugs (AEDs) were studied retrospectively at Hopital Pasteur, Nice;
J Gordon Millichap
doaj   +1 more source

Therapeutic Drug Monitoring of Antiepileptic Drugs

open access: yesJournal of Nepal Medical Association, 2008
Commonly used conventional antiepileptic drugs for pharmacotherapy in epilepsy are phenytoin, carbamazepine and valproic acid. These drugs have complex pharmacokinetic properties leading to fluctuation in their plasma level at given same therapeutic dose.
Geeta Shakya   +3 more
doaj   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang   +2 more
wiley   +1 more source

Cognitive Side Effects of Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2004
Available studies of the cognitive side effects of traditional and newer antiepileptic drugs (AEDs) are reviewed by researchers at Georgetown University Medical Center, Washington, DC.
J Gordon Millichap
doaj   +1 more source

Prescription Sequence Symmetry Analysis of Glucagon‐Like Peptide‐1 Receptor Agonists and Neuropsychiatric Conditions

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez   +6 more
wiley   +1 more source

Antiepileptic drugs: interaction, specificity of application

open access: yesФармацевтичний журнал, 2018
When carrying out the pharmaceutical care of a particular patient (for example, an epileptic patient), the doctor and pharmacist must take into account the possible fact of interaction between anticonvulsants among themselves (with polytherapy) or with ...
N. A. Prуlуpko, Ya. O. Grynkiv
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit   +7 more
wiley   +1 more source

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