Results 81 to 90 of about 75,779 (301)
New choices of antiepileptic drugs
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 doi: 10.3969/j.issn.1672-6731.2014.12 ...
Xue-feng WANG
doaj
Basic Mechanisms of Action of the Antiepileptic Drugs
Acta Medica Bulgarica, 2017 Available antiepileptic drugs interact with a variety of different molecular targets. The mechanism of action of most anticonvulsants is most often complex with a number of affected regions.
Kuzmanova R., Stefanova I.
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi +3 more
wiley +1 more source
Revista Brasileira de Anestesiologia, 2014 Background and objectives:The induction and inhibition of cytochrome P450 isoenzymes by antiepileptic drugs lead to changes in the clearance of anesthetic drugs eliminated via hepatic metabolism.
Isil Davarci +7 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen +4 more
wiley +1 more source
Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]
, 2013 <p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan +23 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway +24 more
wiley +1 more source
Cleveland Clinic Journal of Medicine, 1989 In contrast with the situation only a decade ago, a profusion of new potential AEDs has been introduced for world-wide clinical testing. Which, if any, of these compounds will be added to the physician's armamentarium against epileptic seizures is unknown, but the continuing flow of testable compounds augurs well for the future.
openaire +2 more sources
Evaluation of perampanel as monotherapy for focal seizures: Experience from open-label extension studies [PDF]
, 2017 Perampanel, a selective, non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is approved for adjunctive treatment of focal seizures, with or without secondarily generalized seizures, and for primary ...
Cartwright, Karen +5 more
core +1 more source