Results 101 to 110 of about 75,779 (301)

Adherence to antiepileptic drugs among children attending a tertiary health unit in a low resource setting

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: Epilepsy is one of the neglected and highly stigmatised diseases, yet it is very common affecting about 70 million people worldwide. In Uganda, the estimated prevalence of epilepsy is 13% with about 156 new cases per 100,000 people per year.
Rose Nazziwa   +4 more
doaj   +1 more source

Cognitive Side Effects of Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2004
Available studies of the cognitive side effects of traditional and newer antiepileptic drugs (AEDs) are reviewed by researchers at Georgetown University Medical Center, Washington, DC.
J Gordon Millichap
doaj   +1 more source

Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]

open access: yes, 2014
Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core   +2 more sources

Diffusion of Carbamazepine in Hydrophobic Zeolites: A Comparative Study Using Classical and Machine‐Learned Potentials

open access: yesChemistry – A European Journal, EarlyView.
Can hydrophobic, shape‐selective zeolites efficiently remove the persistent pharmaceutical CBZ from water? This work moves beyond the static picture of interaction energies by modeling diffusion with umbrella sampling and machine‐learned potentials. Even high intrinsic diffusion barriers can be overcome through exergonic adsorption from water, yielding
Jakob Brauer   +4 more
wiley   +1 more source

Antiepileptic drugs: interaction, specificity of application

open access: yesФармацевтичний журнал, 2018
When carrying out the pharmaceutical care of a particular patient (for example, an epileptic patient), the doctor and pharmacist must take into account the possible fact of interaction between anticonvulsants among themselves (with polytherapy) or with ...
N. A. Prуlуpko, Ya. O. Grynkiv
doaj   +1 more source

Antiepileptic drugs in pregnancy and lactation [PDF]

open access: yes, 2008
No antiepileptic drug is completely safe to use in pregnancy as the risk of fetal abnormality is increased. Valproate should be avoided if possible because of the risk of major malformations.
Lander, Cecile M.
core   +1 more source

Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
We compared the initial efficacy of denosumab (Dmab) and zoledronate (ZOL) in treatment‐naive patients with osteoporosis. This cohort study, based on TriNetX data, evaluated the risks of fractures and mortality using Kaplan–Meier survival analyses, with hazard ratios (HRs) and 95% confidence intervals (CIs).
Ko‐Hsiu Lu   +2 more
wiley   +1 more source

Drug Critical Limits for Urgent Physician Notification

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang   +3 more
wiley   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

open access: yesEpileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini   +6 more
wiley   +1 more source

Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis

open access: yesReproductive Biology and Endocrinology, 2011
Background The present study compares antiepileptic drugs and aromatase (CYP19) inhibitors for chemical and structural similarity. Human aromatase is well known as an important pharmacological target in anti-breast cancer therapy, but recent research ...
Mustata Gabriela, Muftuoglu Yagmur
doaj   +1 more source

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