Results 121 to 130 of about 1,132,887 (301)

Progress in the Diagnosis and Treatment of Infantile Epileptic Spasm Syndrome

open access: yes罕见病研究
Infantile epileptic spasm syndrome (IESS) is a new concept proposed recently. IESS is a unique and age-specific refractory epilepsy syndrome. The recent advances in molecular biology, neuroimmunology and the in-depth study of anti-epileptic mechanism in ...
ZHENG Lu   +6 more
doaj   +1 more source

Antiepileptic Drugs, Reaction Time, and Impulsivity

open access: yes, 1993
The effects of antiepileptic drugs (AED) on reaction time, attention, and impulsivity in 111 epileptic children, aged 5 to 13 years, are reported from the Children’s Hospital of Los Angeles and University of Southern California School of ...
J Gordon Millichap
core   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

Bone and calcium metabolism and antiepileptic drugs

open access: yes, 2010
There is increasing evidence suggesting that epilepsy and its treatment can affect bone mineralization and calcium metabolism. Many studies have shown a significant reduction in bone mineral density in patients treated with classic (phenobarbital ...
COPPOLA, Giangennaro   +16 more
core   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

NEW BIOMOLECULAR TARGETS FOR ANTIEPILEPTIC DRUGS

open access: yesЭпилепсия и пароксизмальные состояния, 2016
The review presents data on new antiepileptic drugs (AEDs), which have been applied in medical practice in recent years. New AEDs have different spectrum of pharmacological effects and mechanism of action. The authors presented the classification of AEDs
T. A. Voronina   +4 more
doaj  

Use of antiepileptic drugs in pregnancy, Sweden 1996–2013.

open access: yes, 2019
Note = Year represents year of delivery. The curve labeled "any antiepileptic drug" includes all drugs in chapter N03 of the Anatomical Therapeutic Chemical (ATC) classification system.
Thomas McElrath (5431463)   +7 more
core   +1 more source

Epilepsy surgery through a reproductive lifespan lens

open access: yes
Epilepsia, EarlyView.
Aisha A. Abdulrazaq   +2 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

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