Results 91 to 100 of about 14,357 (275)

Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis

Saudi Journal of Kidney Diseases and Transplantation, 2018
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property.
Kar Wah Fuah, Christopher T. S. Lim, Daniel C. L. Pang, Jin Shyan Wong   +3 more
doaj   +1 more source

Mortality Benefit of Tranexamic Acid for Hemorrhage With Concurrent Traumatic Brain Injury: Outcomes From a Prospective Cohort Study in a High‐Trauma, Prolonged Care Setting

World Journal of Surgery, Volume 50, Issue 1, Page 233-243, January 2026.
Early TXA administration (≤ 3 h) in concurrent hemorrhage and TBI was significantly associated with a 22% reduction in mortality at 7 days. TXA treatment was also associated with a significant 29% lower odds of organ failure and non‐significant 11% odds of good neurologic recovery.
Julia M. Dixon, Adane F. Wogu, Maria D. Rodriguez, Dale Barnhart, Rachel Patel, Hendrick J. Lategan, George Oosthuizen, Janette Verster, Shaheem de Vries, Craig Wylie, EpiC Study Site Collaborators, Elaine Erasmus, Steven G. Schauer, Nee‐Kofi Mould‐Millman   +13 more
wiley   +1 more source

Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. [PDF]

, 2017
BACKGROUND: The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients. However, the effect appeared to depend on how soon after injury TXA treatment was started. Treatment within 3 h reduced bleeding
Edwards, Phil, Joshi, Miland, Ker, Katharine, Mahmood, Abda, Prieto, David, Roberts, Ian, Shakur, Haleema   +6 more
core   +6 more sources

ANTIFIBRINOLYTIC ACTIVITY IN NORMAL PREGNANCY [PDF]

Journal of Clinical Pathology, 1960
It is found that serum antifibrinolytic activity is inhibitory both to the spontaneous fibrinolytic activity and to the activity of streptokinase-activated plasminogen. The titres of serum antiplasmin activity during gestation, labour, and the puerperium are all of the same order and do not differ from those in non-pregnant women. The
openaire   +2 more sources

Liver Transplant Anesthesia Practice Patterns in Canada, Australia, and New Zealand: Results From a Multi‐National Survey

Clinical Transplantation, Volume 40, Issue 1, January 2026.
Abstract Background Liver transplantation is the only curative treatment for end‐stage liver disease, yet perioperative management is complex and high‐risk. Variations in anesthetic practices may influence outcomes, but benchmarks are scant. This study characterizes liver transplant anesthesia practices in Canada, Australia, and New Zealand to identify
Elizabeth van Rooy, Daniel Sellers, Stuart McCluskey, Cara Crouch   +3 more
wiley   +1 more source

Dental extraction in patients rece iving dual antiplatelet therapy [PDF]

, 2015
Background: Dual antiplatelet therapy consists of administering antiplatelet (antiaggregant) drugs (clopidogrel and aspirin) to prevent thrombotic processes, as a preventative measure in patients with acute coronary disease, or in patients ...
Calvo Guirado, José Luis, González Jaranay, Maximino, Gómez Moreno, Gerardo, Moreu Burgos, Gerardo, Peñarrocha Diago, Miguel, Rodriguez Archilla, Alberto, Sánchez Cobo, Paulino, Sánchez Palomino, Paulino   +7 more
core   +2 more sources

Acquired angioedema

Allergy, Asthma & Clinical Immunology, 2010
Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact ...
Cicardi Marco, Zanichelli Andrea
doaj   +1 more source

Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao, Rui Luo, Ying Deng, Hongqiu Yang, Yu Du   +4 more
wiley   +1 more source

Inherited, congenital and acquired disorders by hemostasis (vascular, platelet & plasmatic phases) with repercussions [PDF]

, 2014
The hemostasis alterations, either congenital or hereditary origin, and acquired, are circumstances that hinder oral care to patients who suffer them and also generates in the professional who has to attend, high stress. Bleeding control once established
Arrieta Blanco, Juan José, Cabrerizo Merino, María del Carmen, Martínez López, Federico, Oñate Cabrerizo, Daniel, Oñate Sánchez, Ricardo Elías   +4 more
core  

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial. [PDF]

, 2016
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid has the potential to reduce bleeding and a large randomized controlled trial of its effect on maternal health outcomes in women with PPH (The WOMAN trial) is ...
Aimakhu, Chris O, Bello, Adenike, Fawole, Bukola, Gregg, Meghann, Huque, Sumaya, Kotila, Taiwo, Kuti, Modupe, Ogunbode, Olayinka, Olayemi, Oladapo, Roberts, Ian, Shakur, Haleema   +10 more
core   +2 more sources