Results 91 to 100 of about 6,662 (219)

Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2018
Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property.
Kar Wah Fuah   +3 more
doaj   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S8, Page 34-46, September 2025.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi   +4 more
wiley   +1 more source

Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?

open access: yesJournal of Lipid Research, 2016
Elevated plasma concentrations of lipoprotein (a) [Lp(a)] have been determined to be a causal risk factor for coronary heart disease, and may similarly play a role in other atherothrombotic disorders.
Michael B. Boffa, Marlys L. Koschinsky
doaj   +1 more source

Randomized Clinical Trial on the Efficacy of Oral Tranexamic Acid Versus Topical Tranexamic Acid in Treatment of Melasma

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 9, September 2025.
ABSTRACT Background Melasma is a prevalent skin condition that primarily affects females of reproductive age. Despite the various available treatments, managing melasma is challenging due to frequent relapses and partial responses. Tranexamic acid (TXA) has gained attention as a potential treatment because of its antifibrinolytic and anti‐melanogenic ...
Behrooz Heidary   +4 more
wiley   +1 more source

MANAGEMENT OF THE HAEMOPHILIC PATIENT IN DENTISTRY AND CERVICOFACIAL SURGERY

open access: yesRomanian Journal of Oral Rehabilitation, 2023
In patients with haemophilia, any oral surgery carries the risk of prolonged and excessive bleeding. Close collaboration between haematologists and oral surgeons is necessary to prevent excessive bleeding.
Lidia Cureniuc   +11 more
doaj  

Acquired angioedema

open access: yesAllergy, Asthma & Clinical Immunology, 2010
Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact ...
Cicardi Marco, Zanichelli Andrea
doaj   +1 more source

Inherited, congenital and acquired disorders by hemostasis (vascular, platelet & plasmatic phases) with repercussions [PDF]

open access: yes, 2014
The hemostasis alterations, either congenital or hereditary origin, and acquired, are circumstances that hinder oral care to patients who suffer them and also generates in the professional who has to attend, high stress. Bleeding control once established
Arrieta Blanco, Juan José   +4 more
core  

Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. [PDF]

open access: yes, 2017
BACKGROUND: The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients. However, the effect appeared to depend on how soon after injury TXA treatment was started. Treatment within 3 h reduced bleeding
Edwards, Phil   +6 more
core   +6 more sources

Adherence to local rotational thromboelastometry recommendations in the care of trauma patients: A retrospective cohort study

open access: yesTransfusion, Volume 65, Issue 9, Page 1716-1727, September 2025.
Abstract Background Rotational thromboelastometry (ROTEM) is a blood test that measures hemostatic parameters to guide hemostatic therapy. ROTEM outputs can be cognitively challenging to interpret, which may limit adherence in trauma care. Our objective was to assess hemostatic therapy administration adherence to local ROTEM recommendations.
Vinyas Harish   +7 more
wiley   +1 more source

Effect of antifibrinolytic drugs on transfusion requirement and blood loss during orthotopic liver transplantation: Results from a single center

open access: yesAsian Journal of Transfusion Science, 2008
Background: During orthotopic liver transplantation (OLT), activation of the fibrinolytic system can contribute significantly to perioperative bleeding.
Devi A   +4 more
doaj  

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