Results 241 to 250 of about 18,435 (288)

Intraoperative transfusion management, antifibrinolytic therapy, coagulation monitoring and the impact on short‐term outcomes after liver transplantation—A systematic review of the literature and expert panel recommendations

Clinical Transplantation, 2022
Liver transplantation (LT) is frequently complicated by coagulopathy associated with end‐stage liver disease (ESLD), that is, often multifactorial.
U. Yoon, Justyna Bartoszko, D. Bezinover, G. Biancofiore, K. T. Forkin, Suehana Rahman, M. Spiro, D. Raptis, Yoogoo Kang   +8 more
semanticscholar   +1 more source

Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac Surgery on Cardiopulmonary Bypass: A Systematic Review and Meta-analysis

Anesthesia and Analgesia, 2021
BACKGROUND: Bleeding is one of the commonest complications affecting children undergoing cardiac surgery on cardiopulmonary bypass. Antifibrinolytic drugs are part of a multifaceted approach aimed at reducing bleeding, though sufficiently sized pediatric
K. Siemens, D. Sangaran, B. Hunt, I. Murdoch, S. Tibby   +4 more
semanticscholar   +1 more source

Efficacy and Safety of Antifibrinolytic Drugs in Pediatric Surgery: A Systematic Review

Seminars in Thrombosis and Hemostasis, 2021
Antifibrinolytic drugs are used to reduce blood loss and subsequent transfusions during surgery and following trauma, but the optimal dosing regimen in the pediatric population is still unresolved.
Nadia Thrane Hovgesen, J. Larsen, C. Fenger-Eriksen, A. K. Hansen, A. Hvas   +4 more
semanticscholar   +1 more source

Antifibrinolytic Agents in Plastic Surgery: Current Practices and Future Directions

Plastic and Reconstructive Surgery, 2018
Background: Prevention of blood loss is a chief consideration in plastic and reconstructive surgery. The antifibrinolytic drugs tranexamic acid and &egr;-aminocaproic acid have emerged as promising agents to reduce both perioperative blood loss and ...
Stav Brown, Amy Yao, P. Taub
semanticscholar   +1 more source

DESMOPRESSIN AND ANTIFIBRINOLYTICS

International Anesthesiology Clinics, 1990
Desmopressin appears to be a safe and effective hemostatic agent for use during surgery in patients with mild to moderate hemophilia or von Willebrand disease. Uremic patients also benefit from substitution of desmopressin for cryoprecipitate to control bleeding. The highly variable response to desmopressin by individual patients with hemophilia or von
openaire   +2 more sources

Pharmacokinetics of tranexamic acid in healthy dogs and assessment of its antifibrinolytic properties in canine blood.

American Journal of Veterinary Research, 2018
OBJECTIVE To assess pharmacokinetics of tranexamic acid (TXA) in dogs and assess antifibrinolytic properties of TXA in canine blood by use of a thromboelastography-based in vitro model of hyperfibrinolysis. ANIMALS 6 healthy adult dogs.
Katie E. Osekavage, B. Brainard, Selena L Lane, Mohammed Almoslem, R. Arnold, A. Koenig   +5 more
semanticscholar   +1 more source

Antifibrinolytics and Thrombolytics

2018
There is a balance between activation of the coagulation cascade leading to thrombin and the fibrinolytic system dissolving clots. Antifibrinolytic drugs and fibrinolytic drugs are commonly used in the neurosciences intensive care unit. Antifibrinolytics, mostly tranexamic acid, are used to prevent rebleeding of recently ruptured intracranial aneurysms
Sarah L. Clark, Eelco F. M. Wijdicks
openaire   +1 more source

Antifibrinolytic properties of oxyphenbutazone in vitro

Experientia, 1976
The authors found that oxyphenbutazone (Tanderil®) added to culture medium, in amounts giving a final concentration of 10–100 μg/ml, causes a decrease in the liberation of fibrinolytic agents from explants of various tissues cultured in vitro.
K. Dyster-Aas, Maurizio Pandolfi, Birger Åstedt   +2 more
openaire   +3 more sources

The Antifibrinolytic Activity of Sulfamylon Solution

Plastic and Reconstructive Surgery, 1988
Sulfamylon (mafenide) solution, a potent experimental topical antimicrobial, is used in our burn unit to treat burn wounds both before and after skin grafting. The importance of fibrin to early graft adherence prompted this in vitro study of the effect of Sulfamylon upon fibrin clot.
Daniel J. Weisdorf, Jeffrey H. Aldridge, John O. Kucan, John O. Kucan, John O. Kucan   +4 more
openaire   +3 more sources

Antithrombotics and Antifibrinolytics

2014
Pediatric thromboembolic events are rare, but the incidence of thrombosis in children has dramatically increased over the last decade and appears to be an increasing problem in pediatric tertiary care hospitals. They usually occur as a complication of a primary disease or treatment.
Donald Berry, Sriya Gunawardena
openaire   +2 more sources