Results 111 to 120 of about 54,087 (251)
Clinical and Translational Science, Volume 18, Issue 4, April 2025.ABSTRACT Scientific advancements in pharmacology have revolutionized disease management, significantly enhancing global health. Innovations like biological therapies and mRNA vaccines underscore the field's capacity to address complex conditions and global crises.
Salvatore Di Maria, Alessio Provenzani
wiley +1 more source
Tranexamic acid in the management of traumatic brain injury: a systematic review and meta-analysis with trial sequential analysis [PDF]
Einstein (São Paulo)Introduction Traumatic brain injury is a leading cause of death and disability. Tranexamic acid, an antifibrinolytic agent, holds the potential for managing intracranial hemorrhages secondary to traumatic brain injury.
Thiago Gebrin +5 more
doaj +1 more source
Plasminflammation—An Emerging Pathway to Bradykinin Production
Frontiers in Immunology, 2019 Plasminogen activation is essential for fibrinolysis—the breakdown of fibrin polymers in blood clots. Besides this important function, plasminogen activation participates in a wide variety of inflammatory conditions. One of these conditions is hereditary
Coen Maas
doaj +1 more source
Inhibitors of the Plasminogen/Plasmin system for the treatment of Traumatic Brain Injury [PDF]
, 2023 La plasmina és un enzim proteolític responsable de la degradació de la fibrina, la proteïna estructural dels coàguls sanguinis. És activada a partir del zimogen plasminogen per l’activador tissular del plasminogen (tPA).
Bosch Sanz, Oriol
core
Languages for Mobile Agents [PDF]
arXiv, 2015 Mobile agents represent a new model for network computing. Many different languages have been used to implement mobile agents. The characteristics that make a language useful for writing mobile agents are: (1) their support of agent migration, (2) their support for agent-to-agent communication, (3) how they allow agents to interact with local resources,
arxiv
Inhibition of Fibrinolysis by Coagulation Factor XIII [PDF]
, 2017 The inhibitory effect of coagulation factor XIII (FXIII) on fibrinolysis has been studied for at least 50 years. Our insight into the underlying mechanisms has improved considerably, aided in particular by the discovery that activated FXIII cross-links ...
Rijken, D.C. (Dingeman) +1 more
core +5 more sources
Case Reports in Hematology, 2012 Glanzmann’s thromboasthenia (GT) is a rare platelet disorder, due to membrane defects involving glycoprotein GP IIb/IIIa complex. Symptoms appear in infancy with episodes of bruising, gingival bleeding, epistaxis, or at the time of menarche acute episode
Nazli Hossain +2 more
doaj +1 more source
VAIN: Attentional Multi-agent Predictive Modeling [PDF]
arXiv, 2017 Multi-agent predictive modeling is an essential step for understanding physical, social and team-play systems. Recently, Interaction Networks (INs) were proposed for the task of modeling multi-agent physical systems, INs scale with the number of interactions in the system (typically quadratic or higher order in the number of agents).
arxiv
On‐demand treatment of bleeds in haemophilia patients with inhibitors: strategies for securing and maintaining predictable efficacy with recombinant activated factor VII [PDF]
, 2011 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90042/1/j.1365-2516.2011.02612.x ...
Abshire +38 more
core +1 more source
North American Spine Society Journal, 2021 Background: For adults undergoing complex, multilevel spinal surgery, tranexamic acid (TXA) is an antifibrinolytic agent used to reduce blood loss. The optimal dosing of intravenous TXA remains unclear.
Roman Rahmani +4 more
doaj