Results 121 to 130 of about 5,327 (168)

The effect of antifibrinolytic agents on wound healing

International Journal of Oral and Maxillofacial Surgery, 1988
The effect on the tensile strength of healing wounds of 2 of the most commonly used antifibrinolytic substances, tranexamic acid and epsilon-aminocaproic acid, has been studied in white rats. 2 symmetrical linear lines were made on the dorsal skin, in 1 of which was injected 1 ml of the test solution. The incisions were closed with interrupted sutures,
G Björlin, I M Nilsson
exaly   +3 more sources

Antifibrinolytic agents in cardiac surgery: Current controversies

Seminars in Thoracic and Cardiovascular Surgery, 2005
Antifibrinolytic agents play a prominent role in adult cardiac surgery. This article is a review of the modern published experience of antifibrinolytic agent use in adult cardiac surgery. The use of tranexamic acid, epsilon-aminocaproic acid, and aprotinin is examined during primary cardiac surgery, deep hypothermic circulatory arrest, reoperative ...
John D PUŜKAŜ
exaly   +3 more sources

The effect of antifibrinolytic agents on wound healing in vitro

Experientia, 1977
The effect of antifibrinolytic agents (antiplasminogen activators) on wound healing was studied in vitro. All these substances caused the proliferating epithelium to change direction and migrate to stratum corneum, resulting in a everted epiboly formation.
G T Gustafson
exaly   +3 more sources

The Use of Antifibrinolytic Agents in Spine Surgery

Journal of Bone and Joint Surgery - Series A, 2008
Antifibrinolytic agents have been shown to decrease the blood loss associated with major orthopaedic surgical procedures. Spine surgery, particularly procedures performed for deformity correction and procedures involving long arthrodesis constructs, can be associated with a large amount of blood loss requiring blood transfusions.
J Brian, Gill, Yoona, Chin, Andrew, Levin, Du, Feng   +3 more
exaly   +3 more sources

Monitoring the Effect of Antifibrinolytic Agents and Thrombolytic Agents

Abstract Clinical conditions that may require the use of an antifibrinolytic agent (tranexamic acid or aminocaproic acid) to control fibrinolysis-associated bleeding are listed. Tests to monitor antifibrinolytic therapy are unavailable in most laboratories.
Gene Gulati, Dorothy Adcock, Ruben Rhoades   +2 more
exaly   +2 more sources

Pharmacological agents: antifibrinolytics and desmopressin

Best Practice & Research Clinical Anaesthesiology, 2010
This article provides an overview of the scientific evidence regarding the efficacy and safety of antifibrinolytic agents and desmopressin to reduce surgical blood loss. The synthetic derivatives of lysine are the only antifibrinolytics available in clinical practice since the withdrawal of aprotinin.
Yves, Ozier, Lorenn, Bellamy
openaire   +2 more sources

Cimetidine—an Antifibrinolytic Agent?

Scandinavian Journal of Gastroenterology, 1983
The mucosal fibrinolytic activity was estimated in 14 patients with duodenal ulcer before and after 4 weeks' treatment with cimetidine. A significant reduction in fibrinolytic activity in the corpus and antrum mucosa was found after treatment. In patients with healed ulcer after treatment, the activity was lower than in patients with unhealed ulcers ...
openaire   +2 more sources

Antifibrinolytic agents in subarachnoid haemorrhage

Journal of Neurology, 1987
For many years clinicians have used antifibrinolytic agents to try to reduce rebleeding after subarachnoid haemorrhage. Early studies of their effectiveness produced conflicting results. This paper re-evaluates the available trials and considers benefits in the light of potential complications.
openaire   +2 more sources

Antifibrinolytic Agents in the Management of Traumatic Hyphema

Archives of Ophthalmology, 1983
Clinical confusion often exists when therapeutic alternatives for a particular disease have not been rigorously compared. This problem is typical of the series of clinical decisions required in the management of traumatic hyphema and its complications. For example, should the patient (1) be admitted to the hospital, (2) undergo bilateral or unilateral ...
openaire   +2 more sources

Antifibrinolytic Agents and Desmopressin as Hemostatic Agents in Cardiac Surgery

The Annals of Pharmacotherapy, 2001
OBJECTIVE: To review the use of systemic hemostatic medications for reducing bleeding and transfusion requirements with cardiac surgery. DATA SOURCES: Articles were obtained through computerized searches involving MEDLINE (from 1966 to
openaire   +2 more sources