Results 181 to 190 of about 316,555 (354)

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

MoMtg1 Acts as a Novel Transcriptional Repressor of MoSwi6 During Appressorium‐Mediated Penetration in the Rice Blast Fungus

Advanced Science, EarlyView.
Appressoria are specialized penetration structures for many plant pathogenic fungi, demanding precise cell cycle control. This study unveils MoMtg1 as a transcriptional repressor of MoSwi6, orchestrating MoCYC1 expression during turgor‐driven cell cycle progression to enable appressorium‐mediated penetration. Moreover, a small‐molecule inhibitor ZS1619
Xingyu Wang, Ting Zhang, Qi Li, Chang‐An Ji, Lin Huang, Mingzhi Zhang, Leiyun Yang, Xinyu Liu, Muxing Liu, Gang Li, Zhengguang Zhang, Haifeng Zhang   +11 more
wiley   +1 more source

Studies on Fungicides. VII. Synthesis and Antifungal Activity of Some Pyrazole Derivatives.

, 1964
Jiro Kinugawa, Michihiko Ochiai, Chikashi Matsumura, Hiroichi Yamamoto   +3 more
openalex   +2 more sources

Antifungal Activity of Alkylxylylene-Bis-Isothiuronium Chlorides [PDF]

, 1970
Gail Shelley, D. Huisingh, P. B. Hamilton   +2 more
openalex   +1 more source

Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

Advanced Science, EarlyView.
The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua, Xuyang Ding, Yanan Wu, Di Zhang, Xinlin Hu, Ping Yang, Jiameng Li, Yi Tan, Junbo Liu, Mingjie Zhang, Min Zhang, Xiaotian Liu, Hongjun Yu   +12 more
wiley   +1 more source

Synthesis and Antifungal Activity of 2-Chloro-4-amino-5-(p-halogenophenoxy) phenylthiocyanate Compounds. I.

, 1967
Yoshiki Hamada, Hisayoshi Sugihara, Yosio Ito, K. ITO, S Tomomatsu   +4 more
openalex   +2 more sources

Synergistic antifungal activity and reduced toxicity of liposomal amphotericin B combined with gramicidin S or NF [PDF]

, 1987
Roy L. Hopfer, R T Mehta, Gabriel López-Berestein   +2 more
openalex   +1 more source

Fungicidal activity of truncated analogues of dihydrosphingosine [PDF]

, 2008
Cammue, Bruno PA, Chow, Kuen K, François, Isabelle EJA, Hillaert, Ulrik, Meert, Els MK, Thevissen, Karin, Van Calenbergh, Serge   +6 more
core   +1 more source

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang, Luju Jiang, Shuqi Cai, Zheqi Weng, Yuheng Zhu, Zhi‐Wei Cai, Hui Li, Qing Li, Li‐Peng Hu, Hong‐Fei Yao, Rong Hua, Yu Zhao, Dongxue Li, Xiao‐Mei Yang, Jun‐Feng Zhang, Shu‐Heng Jiang   +15 more
wiley   +1 more source

Correction: Antifungal activity of guanidine compounds. [PDF]

Braz J Microbiol
Eguiluz ADB, Orlandi CBC, Do Espírito Santo RD, Zampieri EH, Dos Anjos LR, Giannini MJSM, Fusco-Almeida AM, Valentini SR, Zanelli CF, de Souza-Moreira TM, González ERP.   +10 more
europepmc   +1 more source