Results 61 to 70 of about 316,555 (354)

Tiny but mighty, an exploration of microbes and plants as sources of small novel bioactive compounds against invasive mycoses.

SURE Journal: (Science Undergraduate Research Experience Journal), 2023
Despite the high mortality rate involved with invasive cerebral mycoses, there is a relative lack of research available around antifungals capable of crossing the blood brain barrier. In this study the metabolites of four plants (Crocus vernus, Miniature
Hannah Mai Peacock, James Anthony O'Connor   +1 more
doaj   +1 more source

Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]

, 2008
Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian, Schäfer-Korting, Monika, Schöllmann, C.   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Antifungal activity of lactic acid bacteria [PDF]

, 2003
Enrichment culture techniques produced more than 1200 isolates of lactic acid bacteria (LAB) that were screened for antifungal activity against the indicator mould Aspergillus fumigatus. Approximately 10% of the LAB were active, but only 4% had medium or
Magnusson, Jesper
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Chalcone derivatives as potential antifungal agents: Synthesis, and antifungal activity

Journal of Advanced Pharmaceutical Technology & Research, 2015
Much research has been carried out with the aim to discover the therapeutic values of chalcone derivatives. Chalcones possess wide range of pharmacological activity such as antibacterial, antimalarial, antiprotozoal, antitubercular, anticancer, and ...
Deepa Gupta, D K Jain
doaj   +1 more source

Rhizobacteria of Maize and Their Antifungal Activities [PDF]

Applied and Environmental Microbiology, 1987
During the growing season of 1984, the rhizobacteria (including organisms from the rhizosphere soil, the rhizoplane, and internal root zones) of 47 maize plants (two varieties) sampled from different locations in France and at different growth stages were inventoried. Isolates were characterized by sodium dodecyl sulfate-polyacrylamide gel
Frederik Leyns, J. Swings, Yves Papon, Bart Lambert, Luk Van Rooyen, F. Gosselé   +5 more
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina, Jamison, Matthew T, Molinski, Tadeusz F, Wang, Xiao   +3 more
core  

Vertebrate Hosts as Islands: Dynamics of Selection, Immigration, Loss, Persistence, and Potential Function of Bacteria on Salamander Skin. [PDF]

, 2016
Skin bacterial communities can protect amphibians from a fungal pathogen; however, little is known about how these communities are maintained. We used a neutral model of community ecology to identify bacteria that are maintained on salamanders by ...
Harris, Reid N, Knight, Rob, Loudon, Andrew H, McKenzie, Valerie J, Parfrey, Laura Wegener, Schmidt, Thomas M, Van Treuren, William, Venkataraman, Arvind, Woodhams, Douglas C   +8 more
core   +2 more sources