Results 191 to 200 of about 200,239 (330)

Genome Mining Reveals a Novel Nephthenol‐Producing Diterpene Synthase from the Sandfly Lutzomyia Longipalpis

open access: yesChemBioChem, EarlyView.
The discovery of a terpene synthase of insect origin that makes the apparently cryptic product nephthenol from geranylgeranyl diphosphate sheds light on hidden biosynthetic potential. Populations of the sandfly, Lutzomyia longipalpis, use the diterpene sobralene as a sex/aggregation pheromone, which is likely produced in the insect through the activity
Charles Ducker   +6 more
wiley   +1 more source

Boosting Antibiotic Efficacy of Azole Drugs against Methicillin‐Resistant Staphylococcus Aureus by Coordination to Rhenium Carbonyl Complexes

open access: yesChemBioChem, EarlyView.
Coordination of antifungal azoles to rhenium di‐ and tricarbonyl complexes results in compounds with enhanced antimicrobial efficacy—up to 32‐fold minimum inhibitory concentration improvement—against methicillin‐sensitive and methicillin‐resistant Staphylococcus aureus over parent azoles.
Kevin Schindler   +12 more
wiley   +1 more source

On-Resin Assembly of Macrocyclic Inhibitors of <i>Cryptococcus neoformans</i> May1: A Pathway to Potent Antifungal Agents. [PDF]

open access: yesJ Med Chem
Kryštůfek R   +17 more
europepmc   +1 more source

Sustainable One‐Pot Synthesis of N‐Substituted Pyrroles Using a Multifunctional Cobalt‐Based Catalyst

open access: yesChemCatChem, EarlyView.
The one‐pot synthesis of N‐substituted pyrroles from nitrobenzene and 2,5‐hexanodione is first ever reported with >99% conversion and >99% chemoselectivity, in a green solvent, using a non‐noble metal‐based catalyst and hydrogen as a reductant under mild reaction conditions simultaneously.
Jose Luis del Río‐Rodríguez   +3 more
wiley   +1 more source

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