Results 21 to 30 of about 200,239 (330)
Chemosensitization as a means to augment commercial antifungal agents
Frontiers in Microbiology, 2012 Antimycotic chemosensitization and its mode of action are of growing interest. Currently, use of antifungal agents in agriculture and medicine has a number of obstacles.
Bruce C Campbell +2 more
doaj +1 more source
Statins as antifungal agents [PDF]
, 2011 This poster paper describes the objectives, approach and use casesof the EC FP7 Integrated Project PERICLES. The project beganon 1st February 2013 and runs for four years.
Baxter, Rob +18 more
core +1 more source
Advances in Antifungal Drug Development: An Up-To-Date Mini Review
Pharmaceuticals, 2021 The utility of clinically available antifungals is limited by their narrow spectrum of activity, high toxicity, and emerging resistance. Antifungal drug discovery has always been a challenging area, since fungi and their human host are eukaryotes, making
Ghada Bouz, Martin Doležal
doaj +1 more source
Antimicrobial activity, synergism and inhibition of germ tube formation by Crocus sativus-derived compounds against Candida spp [PDF]
, 2016 The limited arsenal of synthetic antifungal agents and the emergence of resistant Candida strains have prompted the researchers towards the investigation of naturally occurring compounds or their semisynthetic derivatives in order to propose new ...
ANGIOLELLA, Letizia +4 more
core +2 more sources
Pediatric antifungal agents [PDF]
Current Opinion in Infectious Diseases, 2009 In immunocompromised hosts, invasive fungal infections are common and fatal. In the past decade, the antifungal armamentarium against invasive mycoses has expanded greatly. The purpose of the present report is to review the most recent literature addressing the use of antifungal agents in children.Most studies evaluating the safety and efficacy of ...
Michael Cohen-Wolkowiez +3 more
openaire +3 more sources
Biogenic silver nanoparticles as antifungal agents
Frontiers in Chemistry, 2022 In recent years, an increase in multidrug-resistant fungal strains has been observed, which, together with the limited number of clinically available antifungal agents, highlights the need for the development of new antifungal agents.
Javier Mussin, Gustavo Giusiano
doaj +1 more source
In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]
, 2017 Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth +5 more
core +1 more source
Tacrolimus as Antifungal Agent
Acta Chimica Slovenica, 2019 Tacrolimus (FK506) is an immunosuppressant drug widely used to avoid organ rejection in transplant patients. It has a profound influence on the cellular stress response by interfering with the calmodulin-calcineurin signaling pathway. In this context FK506 also became a valuable antifungal drug in medical care. Here it is shown in vitro that tacrolimus
Fatuma Meyer +4 more
openaire +5 more sources
Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]
, 2011 Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
A Lupetti +69 more
core +9 more sources
Pharmaceutics, 2020 Pulmonary aspergillosis (PA), a pulmonary fungal infection caused by Aspergillus spp., is a concern for immunocompromised populations. Despite substantial research efforts, conventional treatments of PA using antifungal agents are associated with ...
Shen Nam Cheng +6 more
doaj +1 more source