Results 41 to 50 of about 134,309 (205)
Antifungal Activities of SCY-078 (MK-3118) and Standard Antifungal Agents against Clinical Non-Aspergillus Mold Isolates [PDF]
, 2015 The limited armamentarium of active and oral antifungal drugs against emerging non-Aspergillus molds is of particular concern. Current antifungal agents and the new orally available beta-1,3-d-glucan synthase inhibitor SCY-078 were tested in vitro ...
Frédéric Lamoth +3 more
core +1 more source
, 2022 Fungi are a diverse, heterogeneous group of eukaryotes, serving as friend and foe of humans for centuries. Since ancient times, fungi have been used in food and beverage-making processes and, more recently, have been used for diverse antibiotics ...
Sciturro, Monica +2 more
core +1 more source
Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae [PDF]
, 2013 Saccharomyces cerevisiae is a proven model to investigate the effects of small molecules and drugs on fungal and eukaryotic cells. In this study, the mode of action of an antifungal metabolite, 2,4-diacetylphloroglucinol (DAPG), was determined.
Troppens, Danielle M. +9 more
core +1 more source
Pharmaceutics, 2020 Pulmonary aspergillosis (PA), a pulmonary fungal infection caused by Aspergillus spp., is a concern for immunocompromised populations. Despite substantial research efforts, conventional treatments of PA using antifungal agents are associated with ...
Shen Nam Cheng +6 more
doaj +1 more source
New Antifungal Agents with Azole Moieties
Pharmaceuticals, 2022 Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
Melissa Martins Teixeira +3 more
doaj +1 more source
Immunomodulation for the Treatment of Fungal Infections: Opportunities and Challenges
Frontiers in Cellular and Infection Microbiology, 2020 Opportunistic fungal infections are major causes of morbidity and mortality in patients with single or multiple defects in their immunity. Antifungal agents targeting the pathogen remain the treatment of choice for fungal infections.
Muluneh Ademe
doaj +1 more source
Natural antifungal agents for food preservation [PDF]
Benha Veterinary Medical Journal, 2020 The increasing societal demand for less processed and more natural food products—while conserving those products’ quality, safety, and shelf-life—has raised the question of chemical preservative replacement. In this context, bacteria and fungi as well as
Mahmoud Hammad +2 more
doaj +1 more source
, 2010 Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Sonashia Velho-Pereira +1 more
core +1 more source
, 2013 Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice.
A. Loyse +10 more
core +1 more source
New antifungal strategies and drug development against WHO critical priority fungal pathogens
Frontiers in Cellular and Infection MicrobiologyFungal infections pose a significant threat to human health, particularly in immunocompromised individuals, driving a sustained increase in the demand for effective antifungal agents.
Yanjian Li +7 more
doaj +1 more source