Results 41 to 50 of about 219,275 (300)

Synthesis and antifungal activity of new O-alkylamidoximes

Bioscience Journal, 2021
The continuous prospection for molecules that may be useful in the development of new therapeutic agents is a highly relevant issue, mainly because the launch of new drugs on the market does not accompany the emergence of new resistant microorganisms ...
Maria Verônica Sales Barbosa, Alana Karoline Penha Nascimento, Rodrigo Ribeiro Alves Caiana, Cosme Silva Santos, Wylly Araújo Oliveira, Paulo Henrique Menezes, Juliano Carlo Rufino Freitas   +6 more
doaj   +3 more sources

Chalcone derivatives as potential antifungal agents: Synthesis, and antifungal activity

Journal of Advanced Pharmaceutical Technology & Research, 2015
Much research has been carried out with the aim to discover the therapeutic values of chalcone derivatives. Chalcones possess wide range of pharmacological activity such as antibacterial, antimalarial, antiprotozoal, antitubercular, anticancer, and ...
Deepa Gupta, D K Jain
doaj   +1 more source

Antinomic natural self-protection mechanism in long-lasting woods: a case study with three tropical species from French Guiana [PDF]

, 2009
We demonstrate in this work through 3 examples that Amazonian trees may specialize longlasting woods by means of at least to different approaches. Wallaba impregnates its wood with large amounts of weakly antifungal compounds acting in synergy, while ...
Amusant, Nadine, Beauchêne, Jacques, Eparvier, Véronique, Espindola, Laila S., Herbette, Gaëtan, Rodrigues, Alice M.S., Royer, Mariana, Stien, Didier, Thibaut, Anne, Thibaut, Bernard   +9 more
core  

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source

Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy

Advanced Functional Materials, EarlyView.
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova, Ivan V. Zelepukin, Konstantin G. Shevchenko, Gleb V. Tikhonowski, Lyubov V. Gorelik, Anton A. Popov, Anna S. Sogomonyan, Alina Yu. Kapitannikova, Ivan S. Kazantsev, Dmitry V. Dyubo, Daria A. Panova, Daniil I. Tselikov, Anton A. Minnekhanov, Aziz B. Mirkasymov, Georgy A. Ermolaev, Alexander V. Syuy, Gleb I. Tselikov, Aleksey V. Arsenin, Andrei V. Kabashin, Kostya S. Novoselov, Sergey M. Deyev, Valentyn S. Volkov   +21 more
wiley   +1 more source

Novel Antifungal Agents and Their Activity against Aspergillus Species

Journal of Fungi, 2020
There is a need for new antifungal agents, mainly due to increased incidence of invasive fungal infections (IFI), high frequency of associated morbidity and mortality and limitations of the current antifungal agents (e.g., toxicity, drug–drug ...
Roya Vahedi-Shahandashti, Cornelia Lass-Flörl   +1 more
doaj   +1 more source

Screening of certain Ayurvedic plants extracts against E. turcicum [PDF]

, 2011
The use of chemicals against pathogens is environmentally dangerous, so use of natural inhibitors for disease management is needed. In this work we screen botanical extracts from ayurvedic plants for their antifungal properties against economically ...
Kaushal Kumar Bhati, R. Prasad, Rajesh Singh   +2 more
core   +1 more source

Lateral Flow Assays for the Diagnosis of Invasive Aspergillosis: Current Status. [PDF]

, 2017
Purpose of reviewDiagnosis during early stages of invasive aspergillosis (IA) and targeted antifungal treatment has the potential to improve survival significantly.
Heldt, Sven, Hoenigl, Martin
core   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Synthesis and antifungal activity investigation of a novel clotrimazole derivative

Mongolian Journal of Chemistry, 2014
Azole antifungal agents disrupt fungal ergosterol synthesis that is essential for the formation of fungal cell membrane by preventing 14-α-demethylase enzyme from binding to its substrate.
B Zoljargal, N Davaasuren
doaj   +1 more source