Results 51 to 60 of about 134,309 (205)

Synthesis of Antifungal Heterocycle-Containing Mannich Bases: A Comprehensive Review

open access: yesOrganics, 2023
Mannich bases are a class of organic compounds usually obtained by the condensation reaction between an amine, a compound with active hydrogens, and an aldehyde.
Diego Quiroga, Ericsson Coy-Barrera
doaj   +1 more source

Peptide transport in Candida albicans and synthetic antifungal agents [PDF]

open access: yes, 1986
These studies have characterized the peptide transport systems of Candida albicans, with a view to the rational design of peptide antifungal agents exploiting the 'smugglin' concept.
Shallow, David A.
core  

Antifungal Application of Nonantifungal Drugs

open access: yes, 2014
Candida species are the cause of 60% of all mycoses in immunosuppressed individuals, leading to similar to 150,000 deaths annually due to systemic infections, whereas the current antifungal therapies either have toxic side effects or are insufficiently ...
Wennerberg, Krister   +9 more
core   +1 more source

Compare the efficacy of antifungal agents as primary therapy for invasive aspergillosis: a network meta-analysis

open access: yesBMC Infectious Diseases
Background Several antifungal agents are available for primary therapy in patients with invasive aspergillosis (IA). Although a few studies have compared the effectiveness of different antifungal agents in treating IA, there has yet to be a definitive ...
Ao Liu   +6 more
doaj   +1 more source

Antifungal Drugs: Special Problems Treating Central Nervous System Infections

open access: yesJournal of Fungi, 2019
Treating fungal infections in the central nervous system (CNS) remains a challenge despite the availability of new antifungal agents. Therapy is limited by poor understanding of the kinetic properties of antifungal drugs in the CNS compounded by lack of ...
Elizabeth Dodds Ashley
doaj   +1 more source

Antifungal pharmacodynamics: Latin America's perspective

open access: yesBrazilian Journal of Infectious Diseases, 2017
The current increment of invasive fungal infections and the availability of new broad-spectrum antifungal agents has increased the use of these agents by non-expert practitioners, without an impact on mortality.
Javier M. Gonzalez   +4 more
doaj   +1 more source

Candida Glabrata Fungaemia in a Tertiary Centre in Taiwan: Antifungal Susceptibility and Outcomes

open access: yes, 2011
The proportion of non-albicans candidaemia has increased during recent decades, especially Candida glabrata. We evaluated the antifungal susceptibility, clinical features and outcome of C. glabrata fungaemia treated in a tertiary centre in Taiwan.
RUAN, SHENG-YUAN;HUANG, YU-TSUNG;CHU, CHEN-CHEN;YU, CHONG-JEN;HSUEH, PO-REN   +1 more
core   +1 more source

A review of recent developments in pharmaceutical chemistry on biological evolution of tetrazole derivatives

open access: yesAl-SalamJournal for Medical Science
This review sums up the developments in the biological activity of tetrazole active derivatives in recent days. Some of the deliberated derivatives of tetrazole are at present actively scientifically studied; some of them have biological activity that ...
Zahraa A. Ketan   +4 more
doaj   +1 more source

Resposta in vitro de fungos agentes de micoses cutâneas frente aos antifúngicos sistêmicos mais utilizados na dermatologia In vitro response of cutaneous mycosis fungal agents to the most widely used systemic antifungals in dermatology

open access: yesAnais Brasileiros de Dermatologia, 2009
FUNDAMENTOS - A alta frequência das micoses cutâneas justifica a necessidade de avaliar a possível contribuição da determinação do perfil de susceptibilidade aos antifúngicos in vitro.
Lívia Maria Martins de Almeida   +3 more
doaj   +1 more source

Fungal Spectrum and Susceptibility Against Nine Antifungal Agents in 525 Deep Fungal Infected Cases

open access: yes, 2023
Wenying Cai,1,* Qianqian Ruan,2– 4,* Jiahao Li,1 Li Lin,1 Liyan Xi,1,5 Jiufeng Sun,2,3 Sha Lu1 1Department of Dermatology and Venereology, Sun Yat-sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Guangdong ...
Li J   +6 more
core  

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